Tag: M.W=150-200

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 4897-84-1, formula is C5H9BrO2, Name is Methyl 4-bromobutanoate. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Related Products of 4897-84-1.

Wang, Qingpeng;Chen, Yan;Li, Guoshuai;Liu, Zhifang;Ma, Jing;Liu, Min;Li, Dacheng;Han, Jun;Wang, Bingquan research published 《 Synthesis and evaluation of bi-functional 7-hydroxycoumarin platinum(IV) complexes as antitumor agents》, the research content is summarized as follows. A series of bi-functional 7-hydroxycoumarin platinum(IV) complexes were synthesized, characterized, and evaluated for antitumor activities. The 7-hydroxycoumarin platinum(IV) complexes display moderate to effective antitumor activities toward the tested cell lines and show much potential in overcoming drug resistance of platinum(II) drugs. In reducing microenvironment, the title compounds could be reduced to platinum(II) complex accompanied with two equivalent of coumarin units. By a unique mechanism, the 7-hydroxycoumarin platinum(IV) complex attacks DNA via the released platinum(II) compound, meanwhile it also inhibits the activities of cyclooxygenase by coumarin fragment. This action mechanism might be of much benefit for reducing tumor-related inflammation in the progress of inhibiting tumor proliferation and overcoming cisplatin resistance. The incorporation of 7-hydroxycoumarin leads to significantly enhanced platinum accumulation in both whole tumor cells and DNA. The HSA interaction investigation reveals that the tested coumarin platinum(IV) compound could effectively combine with HSA via van der Waals force and hydrogen bond.

Related Products of 4897-84-1, Methyl 4-bromobutyrate,also as known as 4-Bromobutyric acid methyl ester, is a useful research compound. Its molecular formula is C5H9BrO2 and its molecular weight is 181.03 g/mol. The purity is usually 95%.
4-Bromobutyric acid methyl ester is a synthetic compound that can be used to inhibit the activity of the G1 phase cyclin-dependent kinases. It has been shown to inhibit protein synthesis by alkylating the amino groups of proteins and fatty acids. 4-Bromobutyric acid methyl ester also inhibits the growth of cancer cell lines, such as renal carcinoma cells. The mechanism of action for this drug is not well understood, but it may be due to its ability to bind with monoclonal antibodies and enter kidney cells by passive diffusion., 4897-84-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid, Application of C6H11BrO2

Volpato, Giulia Alice;Colusso, Elena;Paoloni, Lorenzo;Forchetta, Mattia;Sgarbossa, Francesco;Cristino, Vito;Lunardon, Marco;Berardi, Serena;Caramori, Stefano;Agnoli, Stefano;Sabuzi, Federica;Umari, Paolo;Martucci, Alessandro;Galloni, Pierluca;Sartorel, Andrea research published 《 Artificial photosynthesis: photoanodes based on polyquinoid dyes onto mesoporous tin oxide surface》, the research content is summarized as follows. Dye-sensitized photoelectrochem. cells represent an appealing solution for artificial photosynthesis, aimed at the conversion of solar light into fuels or commodity chems. Extensive efforts have been directed towards the development of photoelectrodes combining semiconductor materials and organic dyes; the use of mol. components allows to tune the absorption and redox properties of the material. Recently, we have reported the use of a class of pentacyclic quinoid organic dyes (KuQuinone) chemisorbed onto semiconducting tin oxide as photoanodes for water oxidation In this work, we investigate the effect of the SnO₂ semiconductor thickness and morphol. and of the dye-anchoring group on the photoelectrochem. performance of the electrodes. The optimized materials are mesoporous SnO₂ layers with 2.5 μm film thickness combined with a KuQuinone dye with a 3-carboxylpropyl-anchoring chain: these electrodes achieve light-harvesting efficiency of 93% at the maximum absorption wavelength of 533 nm, and photocurrent d. J up to 350 μA/cm² in the photoelectrochem. oxidation of ascorbate, although with a limited incident photon-to-current efficiency of 0.075%. Calculations based on the d. functional theory (DFT) support the role of the reduced species of the KuQuinone dye via a proton-coupled electron transfer as the competent species involved in the electron transfer to the tin oxide semiconductor. Finally, a preliminary investigation of the photoelectrodes towards benzyl alc. oxidation is presented, achieving photocurrent d. up to 90 μA/cm² in acetonitrile in the presence of N-hydroxysuccinimide and pyridine as redox mediator and base, resp. These results support the possibility of using mol.-based materials in synthetic photoelectrochem.

Application of C6H11BrO2, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Electric Literature of 629-04-9.

Vyas, Akshay;Koshti, Rohit R.;Patel, H. N. research published 《 Effect of terminal metamers and homologous with imine and ester groups on mesomorphism and their DFT study》, the research content is summarized as follows. Three liquid crystalline series with different terminal chains I [R = Me, Et, Pr, etc.; R¹ = (CH₂)₂OCH₂Me, CH(Me)CH₂OMe, (CH₂)₂O(CH₂)₃Me] have been prepared, where two of the series are metamer of each other, and all three series are homologues of each other in context to the terminal chain. All the homologues prepared were found to be enantiotropically mesogenic and screened under a polarizing optical microscope (POM). Differential scanning calorimetry (DSC) technique was used to obtain thermograms of phase transition, enthalpy and entropy change. Characterization of all homologues was carried out by means of standard spectroscopic methods; IR, proton magnetic resonance and UV spectroscopy. Series I [R¹ = CH(Me)CH₂OMe] exhibited polymorphism as of smectic C, smectic A and nematic mesophases, while series I [R¹ = (CH₂)₂OCH₂Me, (CH₂)₂O(CH₂)₃Me] exhibit only smectic A and nematic mesophases. The geometry of all homologues was obtained using DFT calculation, and the effect of the twist angle of the aromatic ring on mesomorphism was examined The effect of branching and length of the broken alkoxy terminal chain on the type of the mesophase was studied by comparing the terminal chain homologues. The prepared series was also compared with four structurally similar compounds to understand the effect of the relative position of groups and the effect of mol. length on thermal stability and mesophase length.

629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., Electric Literature of 629-04-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. HPLC of Formula: 6911-87-1.

Vytla, Devaiah;Kaliyaperumal, Kumargurubaran;Velayuthaperumal, Rajeswari;Shaw, Parinita;Gautam, Raj;Mathur, Arvind;Roy, Amrita research published 《 Visible-Light-Promoted Radical Cyclization of N-Arylvinylsulfonamides: Synthesis of CF₃/CHF₂/CH₂CF₃-Containing 1,3-Dihydrobenzo[c]isothiazole 2,2-Dioxide Derivatives》, the research content is summarized as follows. A photocatalyzed and highly efficient trifluoromethylation of N-arylvinylsulfonamides using com. available CF₃SO₂Cl as the trifluoromethyl radical source under blue LEDs is reported. The reaction proceeds through radical cyclization under mild conditions. An investigation of the substrate scope is performed to establish a general, synthetically useful protocol for the synthesis of novel trifluoromethylated 1,3-dihydrobenzo[c]isothiazole 2,2-dioxides in moderate to high yields. This method is also successfully applied for the synthesis of difluoromethylated and trifluoroethylated 1,3-dihydrobenzo[c]isothiazole 2,2-dioxides in good to excellent yields.

6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., HPLC of Formula: 6911-87-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Application In Synthesis of 70-23-5.

Wagener, Tobias;Heusler, Arne;Nairoukh, Zackaria;Bergander, Klaus;Daniliuc, Constantin G.;Glorius, Frank research published 《 Accessing (Multi)Fluorinated Piperidines Using Heterogeneous Hydrogenation》, the research content is summarized as follows. Fluorinated piperidines are desirable motifs for pharmaceutical and agrochem. research. Nevertheless, general synthetic access remains out of reach. Herein, we describe a simple and robust cis-selective hydrogenation of abundant and cheap fluoropyridines to yield a broad scope of (multi)fluorinated piperidines. This protocol enables the chemoselective reduction of fluoropyridines while tolerating other (hetero)aromatic systems using a com. available heterogeneous catalyst. Fluorinated derivatives of important drug compounds are prepared, and a straightforward strategy for the synthesis of enantioenriched fluorinated piperidines is disclosed.

70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., Application In Synthesis of 70-23-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. SDS of cas: 1575-37-7.

Wagner, Jakub;Zimmermann Crocomo, Paola;Kochman, Michal Andrzej;Kubas, Adam;Data, Przemyslaw;Lindner, Marcin research published 《 Modular Nitrogen-Doped Concave Polycyclic Aromatic Hydrocarbons for High-Performance Organic Light-Emitting Diodes with Tunable Emission Mechanisms》, the research content is summarized as follows. Although bowl-shaped N-pyrrolic polycyclic aromatic hydrocarbons (PAHs) can achieve excellent electron-donating ability, their application for optoelectronics is hampered by typically low photoluminescence quantum yields (PLQYs). To address this issue, we report the synthesis and characterization of a series of curved and fully conjugated nitrogen-doped PAHs. Through structural modifications to the electron-accepting moiety, we are able to switch the mechanism of luminescence between thermally activated delayed fluorescence (TADF) and room-temperature phosphorescence (RTP), and to tune the overall PLQY in the range from 9% to 86%. As a proof of concept, we constructed solid-state organic light-emitting diode (OLED) devices, which has not been explored to date in the context of concave N-doped systems being TADF/RTP emitters. The best-performing dye, possessing a peripheral trifluoromethyl group adjacent to the phenazine acceptor, exhibits yellow to orange emission with a maximum external quantum efficiency (EQE) of 12%, which is the highest EQE in a curved D-A embedded N-PAH to date.

SDS of cas: 1575-37-7, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., 1575-37-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Name: 1-Bromoheptane.

Wahid, Sana;Jahangir, Sajid;Ali Versiani, Muhammad;Mohammed Khan, Khalid;Yik Sung, Yeong;Iqbal, Jamshed;Wadood, Abdul;Kanwal;Ur Rehman, Ashfaq;Arshia;Uzair, Muhammad;Ali Khan, Imtiaz;Taha, Muhammad;Perveen, Shahnaz research published 《 Biology-oriented drug synthesis of nitrofurazone derivatives: Their α-glucosidase inhibitory activity and molecular docking studies》, the research content is summarized as follows. In the present study, twenty (20) structural variants of nitrofurazone were synthesized based on BIODS (Biol.-oriented drug synthesis) approach. The structure elucidation of the synthetic mols. (1-20) was carried out using different spectroscopic techniques, and their α-glucosidase inhibitory activity was also determined The synthetic mols. 1-20 exhibited good α-glucosidase inhibition than the parent, nitrofurazone. Four compounds 2, 4, 6, and 7 showed potential inhibition against α-glucosidase with IC₅₀ values ranging between 0.63 ± 0.25-1.29 ± 0.46 μM as compared to the standard acarbose (IC₅₀ = 2.05 ± 0.41 μM). Nevertheless, compounds 15 (IC₅₀ = 0.74 ± 0.12 μM), and 19 (IC₅₀ = 0.54 ± 0.3 μM) also displayed good α-glucosidase inhibition and compound 19 was the most active compound of the series. Kinetic study of the active compounds 7 and 19 was also carried out to confirm the mode of inhibition. The binding interactions of the most active compounds within the active site of enzyme were determined by mol. docking. Moreover, mol. dynamic simulation of compound 19 was also performed in order to determine the stability of the overall complex (α-glucosidase + c19) in an explicit watery environment. The synthetic mols. were predicted as non-cytotoxic, however, seven compounds 1, 3, 4, 9, 10, 11, and 12 were predicted as carcinogenic.

629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., Name: 1-Bromoheptane

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 4224-70-8, formula is C6H11BrO2, The most pervasive is the naturally produced bromomethane. Recommanded Product: 6-Bromohexanoic acid

Walker, Rebecca;Majewska, Magdalena;Pociecha, Damian;Makal, Anna;Storey, John MD;Gorecka, Ewa;Imrie, Corrie T. research published 《 Twist-Bend Nematic Glasses: The Synthesis and Characterisation of Pyrene-based Nonsymmetric Dimers》, the research content is summarized as follows. A selection of pyrene-based liquid crystal dimers I [n = 5, 6, 8, etc.] , II [n = 5, 6, 11, etc.] and III were prepared, containing either methylene-ether or diether linked spacers of varying length and parity. All the diether linked materials, II, exhibited conventional nematic and smectic A phases, with the exception of II [n = 11] which was exclusively nematic. The methylene-ether linked dimer, I with an even-membered spacer (n=5) was solely nematogenic, but odd-members (n=6, 8, 10) exhibited both nematic and twist-bend nematic phases. Replacement of the cyanobiphenyl fragment by cyanoterphenyl giving III, gave elevated melting and nematic-isotropic transition temperatures, and SmA and SmC_A phases were observed on cooling the nematic phase. Intermol. face-to-face associations of the pyrene moieties drove glass formation, and all these materials had a glass transition temperature at or above room temperature The stability of the glassy twist-bend nematic phase allowed for its study using AFM, and the helical pitch length, P_TB, was measured as 6.3 and 6.7 nm for I [n = 6, 8] , resp. These values were comparable to the shortest pitch of a twist-bend nematic phase measured to date.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., Recommanded Product: 6-Bromohexanoic acid

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid, Reference of 4224-70-8

Walker, Rebecca;Pociecha, Damian;Faidutti, Camilla;Perkovic, Eva;Storey, John M. D.;Gorecka, Ewa;Imrie, Corrie T. research published 《 Remarkable stabilisation of the intercalated smectic phases of nonsymmetric dimers by tert-butyl groups》, the research content is summarized as follows. The synthesis and characterization of two groups of nonsym. dimers, the 1-(4-cyanobiphenyl-4′-yloxy)-ω-(4-alkylbenzylidene-4′-oxy)alkanes and the 1-(4-cyanobiphenyl-4′-yl)-ω-(4-alkylbenzylidene-4′-oxy)alkanes, are reported. The length and parity of the flexible spacer are varied. The tert-Bu homologues show higher m.ps. than the corresponding sec-Bu or Bu substituted dimers and suggesting that chain branching improves packing efficiency within the crystalline structure. The branched chain homologues have a stronger tendency to exhibit smectic phases than the n-butyl-substituted dimers and are exclusively smectic for longer spacers. A comparison of the nematic-isotropic transition temperatures (TNI) for the dimers and containing the different terminal chains is possible for one set of materials, and reveals a large reduction in TNI on passing from the Bu to sec-butyl-substituted, but a much smaller decrease on changing sec-Bu for tert-Bu. A different trend is observed for the smectic A-isotropic transition temperatures for which the tert-Bu substituted dimers and show a higher value than the corresponding sec-Bu homolog, and only marginally lower than that of the n-butyl-substituted dimers. This surprising behavior is interpreted in terms of the ability of the tert-Bu group to pack more efficiently into the intercalated smectic A phase as the spacer length increases.

Reference of 4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Recommanded Product: 4-Bromobenzene-1,2-diamine.

Wang, Ao;Wang, Yawan;Meng, Xin;Yang, Yushe research published 《 Design, synthesis and biological evaluation of novel thiohydantoin derivatives as potent androgen receptor antagonists for the treatment of prostate cancer》, the research content is summarized as follows. Two series of novel thiohydantoin derivatives of enzalutamide I (X = C, N, S; R = Br, Ph, 3-pyridyl) and II (M = C, N; A = di-Me, cyclobutyl, oxetanyl, etc.; X = C, N; Y = O, N-methyl; n = 0, 1) as potent androgen receptor (AR) antagonists were designed and synthesized. Among them, compound II (M = C; A = dimethyl; X = C; Y = O; n =1) was identified as an AR antagonist which was 2.3-fold more potent than enzalutamide. Mol. docking studies were performed to explain the improved potency of II (M = C; A = dimethyl; X = C; Y = O; n =1) at AR. In cell proliferation assays, II (M = C; A = dimethyl; X = C; Y = O; n =1) exhibited similar anti-proliferative activities with enzalutamide against hormone sensitive LNCaP cells and AR-overexpressing LNCaP/AR cells. These data indicated that II (M = C; A = dimethyl; X = C; Y = O; n =1) can be a good lead compound for further structure optimization for the treatment of prostate cancer.

1575-37-7, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., Recommanded Product: 4-Bromobenzene-1,2-diamine

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary