Tag: M.W=150-200

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Recommanded Product: Ethyl 3-bromo-2-oxopropanoate.

Wang, Ao;Wang, Yawan;Meng, Xin;Yang, Yushe research published 《 Design, synthesis and biological evaluation of novel thiohydantoin derivatives as potent androgen receptor antagonists for the treatment of prostate cancer》, the research content is summarized as follows. Two series of novel thiohydantoin derivatives of enzalutamide I (X = C, N, S; R = Br, Ph, 3-pyridyl) and II (M = C, N; A = di-Me, cyclobutyl, oxetanyl, etc.; X = C, N; Y = O, N-methyl; n = 0, 1) as potent androgen receptor (AR) antagonists were designed and synthesized. Among them, compound II (M = C; A = dimethyl; X = C; Y = O; n =1) was identified as an AR antagonist which was 2.3-fold more potent than enzalutamide. Mol. docking studies were performed to explain the improved potency of II (M = C; A = dimethyl; X = C; Y = O; n =1) at AR. In cell proliferation assays, II (M = C; A = dimethyl; X = C; Y = O; n =1) exhibited similar anti-proliferative activities with enzalutamide against hormone sensitive LNCaP cells and AR-overexpressing LNCaP/AR cells. These data indicated that II (M = C; A = dimethyl; X = C; Y = O; n =1) can be a good lead compound for further structure optimization for the treatment of prostate cancer.

70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., Recommanded Product: Ethyl 3-bromo-2-oxopropanoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 4897-84-1, formula is C5H9BrO2, Name is Methyl 4-bromobutanoate, Synthetic Route of 4897-84-1

Wang, Baolei;Chen, Xuehong;Gao, Jianjun;Su, Li;Zhang, Li;Xu, Hongwei;Luan, Yepeng research published 《 Anti-tumor activity evaluation of novel tubulin and HDAC dual-targeting inhibitors》, the research content is summarized as follows. Histone deacetylases (HDACs) have proven to be promising targets for the development of anti-cancer drugs. In this study, we reported a series of novel chalcone based tubulin and HDAC dual-targeting inhibitors. Three compounds inhibited the activities of HDAC and tubulin polymerization simultaneously and displayed anti-proliferative activities toward eleven human tumor cell lines. Compound 8a remarkably induced growth inhibition, apoptosis and G2/M phase arrest of A549 tumor cells. Finally, the inhibitory activities of 8a against HDAC6 and tubulin were rationalized by mol. docking studies.

4897-84-1, Methyl 4-bromobutyrate,also as known as 4-Bromobutyric acid methyl ester, is a useful research compound. Its molecular formula is C5H9BrO2 and its molecular weight is 181.03 g/mol. The purity is usually 95%.
4-Bromobutyric acid methyl ester is a synthetic compound that can be used to inhibit the activity of the G1 phase cyclin-dependent kinases. It has been shown to inhibit protein synthesis by alkylating the amino groups of proteins and fatty acids. 4-Bromobutyric acid methyl ester also inhibits the growth of cancer cell lines, such as renal carcinoma cells. The mechanism of action for this drug is not well understood, but it may be due to its ability to bind with monoclonal antibodies and enter kidney cells by passive diffusion., Synthetic Route of 4897-84-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 4897-84-1, formula is C5H9BrO2, Name is Methyl 4-bromobutanoate. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. COA of Formula: C5H9BrO2.

Wang, Chenxi;Liu, Yuan;Bao, Chunyan;Xue, Yuan;Zhou, Yaowu;Zhang, Dasheng;Lin, Qiuning;Zhu, Linyong research published 《 Phototriggered labeling and crosslinking by 2-nitrobenzyl alcohol derivatives with amine selectivity》, the research content is summarized as follows. Here we report the use of 2-nitrobenzyl alc. (NB) as a photoreactive group with amine selectivity and explore its applications for photoaffinity labeling and crosslinking of biomols. This work confirms that NB is an efficient photoreactive group and has great potential in drug discovery, chem. biol. and protein engineering.

COA of Formula: C5H9BrO2, Methyl 4-bromobutyrate,also as known as 4-Bromobutyric acid methyl ester, is a useful research compound. Its molecular formula is C5H9BrO2 and its molecular weight is 181.03 g/mol. The purity is usually 95%.
4-Bromobutyric acid methyl ester is a synthetic compound that can be used to inhibit the activity of the G1 phase cyclin-dependent kinases. It has been shown to inhibit protein synthesis by alkylating the amino groups of proteins and fatty acids. 4-Bromobutyric acid methyl ester also inhibits the growth of cancer cell lines, such as renal carcinoma cells. The mechanism of action for this drug is not well understood, but it may be due to its ability to bind with monoclonal antibodies and enter kidney cells by passive diffusion., 4897-84-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 5445-17-0, formula is C4H7BrO2, Name is Methyl 2-bromopropanoate. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Electric Literature of 5445-17-0.

Vakarov, Sergey A.;Chulakov, Evgeny N.;Sadretdinova, Liliya Sh.;Kodess, Mikhail I.;Ezhikova, Marina A.;Pervova, Marina G.;Ganebnykh, Ilya N.;Levit, Galina L.;Krasnov, Victor P. research published 《 Kinetic Resolution of Racemic 2-Aryloxy Propionyl Chlorides Using Enantiopure (S)-3,4-Dihydro-3-methyl-2H-[1,4]benzoxazines》, the research content is summarized as follows. Stereoselectivity in the mutual kinetic resolution (KR) of racemic 2-aryloxy propionyl chlorides I [R = Ph, 1-naphthyl, MeS, etc.; Z = O, S, SO₂; Y = Cl] using chiral 3,4-dihydro-3-methyl-2H-[1,4]benzoxazines II [X = H, F] was studied. Based on the results obtained, preparative methods for single enantiomers of a series of 2-aryloxy propionic acids I [Y = OH; stereo = R or S] via acylative KR of their racemates with enantiopure (S)-3,4-dihydro-3-methyl-2H-[1,4]benzoxazines was proposed.

5445-17-0, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., Electric Literature of 5445-17-0

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Formula: C6H7BrN2.

Varma, Reena R.;Pandya, Juhee G.;Vaidya, Foram U.;Pathak, Chandramani;Dabhi, Ravi A.;Dhaduk, Milan P.;Bhatt, Bhupesh S.;Patel, Mohan N. research published 《 DNA interaction, anticancer, antibacterial, ROS and lipid peroxidation studies of quinoxaline based organometallic Re(I) carbonyls》, the research content is summarized as follows. Hetero mononuclear rhenium(I) complexes (I-V) using ligands (L¹-L⁵) [L¹-L⁵ = 11-((2-chlorobenzylidene)hydrazono)-11H-indeno[1,2-b]quinoxaline (L¹), 8-methyl-11-((4-methyl-benzylidene)hydrazono)-11H-indeno[1,2-b]quinoxaline (L²), 11-((4-bromobenzylidene)hydrazono)-8-nitro-11H-indeno[1,2-b]quinoxaline (L³), 11-((4-bromobenzylidene) hydrazono)-8-chloro-11H-indeno[1,2-b]quinoxaline (L⁴), 8-bromo-11-((4-fluorobenzylidene) hydrazono)-11H-indeno[1,2-b]quinoxaline (L⁵)] were synthesized and characterized by spectroscopic method. All the synthesized compounds have biol. importance. DNA interaction studies gave information about the modes of binding and the nucleolytic efficiency of compounds The binding of the rhenium complexes to Herring sperm DNA (HS DNA) was monitored by UV-visible spectroscopy, viscosity measurements, and mol. docking studies; groove binding was suggested as the most possible mode. The DNA-complexes binding strength was measured in terms of intrinsic binding constants In vivo and In vitro cytotoxicity against the eukaryotic and prokaryotic cells gave the toxic nature of the synthesized compounds An antimicrobial study was carried out by estimating MIC (Min. Inhibitory Concentration) against two Gram-pos. (S. aureus, B. subtilis) and three Gram-neg. (S. marcescens, P. aeruginosa, E. coli) bacteria. All synthesized complexes are biol. more active than the corresponding ligands. Complexes were having higher MDA and H₂O₂ production than ligands.

Formula: C6H7BrN2, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., 1575-37-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Application of C6H11BrO2.

Varmazyad, Mahboubeh;Modi, Mira M.;Kalen, Amanda L.;Sarsour, Ehab H.;Wagner, Brett;Du, Juan;Schultz, Michael K.;Buettner, Garry R.;Pigge, F. Christopher;Goswami, Prabhat C. research published 《 N-alkyl triphenylvinylpyridinium conjugated dihydroartemisinin perturbs mitochondrial functions resulting in enhanced cancer versus normal cell toxicity》, the research content is summarized as follows. Dihydroartemisinin (DHA) is an FDA-approved antimalarial drug that has been repurposed for cancer therapy because of its preferential antiproliferative effects on cancer vs. normal cells. Mitochondria represent an attractive target for cancer therapy based on their regulatory role in proliferation and cell death. This study investigates whether DHA conjugated to innately fluorescent N-alkyl triphenylvinylpyridinium (TPVP) perturbs mitochondrial functions resulting in a differential toxicity of cancer vs. normal cells. TPVP-DHA treatments resulted in a dose-dependent toxicity of human melanoma and pancreatic cancer cells, whereas normal human fibroblasts were resistant to this treatment. TPVP-DHA treatments resulted in a G₁-delay of the cancer cell cycle, which was also associated with a significant inhibition of the mTOR-metabolic and ERK1/2-proliferative signaling pathways. TPVP-DHA treatments perturbed mitochondrial functions, which correlated with increases in mitochondrial fission. In summary, TPVP mediated mitochondrial targeting of DHA enhanced cancer cell toxicity by perturbing mitochondrial functions and morphol.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., Application of C6H11BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Related Products of 1575-37-7.

Vasu, Amrutham;Naresh, Mameda;Krishna Sai, Gajula;Divya Rohini, Yennamaneni;Murali, Boosa;Ramulamma, Madasu;Ramunaidu, Addipilli;Narender, Nama research published 《 A heterogeneous catalytic strategy for facile production of benzimidazoles and quinoxalines from primary amines using the Al-MCM-41 catalyst》, the research content is summarized as follows. This study reported a straightforward heterogeneous catalytic (Al-MCM-41) approach to synthesize benzimidazoles I [R = n-Pr, cyclohexyl, Ph, etc.; R¹ = H, 5-Me, 5,6-di-Cl, etc.; R² = H, Bn, CH₂CH₂Ph] and quinoxalines II [R³ = H, 6-Me, 6-Br, etc.; R⁴ = H, 4-MeC₆H₄, 4-ClC₆H₄, etc.] from primary amines under solvent-free conditions. The Al-MCM-41 catalyst was prepared using a hydrothermal method and characterized by various anal. techniques. The probability and limitations of the catalytic methodol. were presented with various substrates. The catalytic method grants an attractive route to a wide variety of benzimidazole and quinoxaline moieties with good to excellent yields. The gram scale reaction and reusability (up to five cycles) of the Al-MCM-41 catalyst would greatly benefit industrial applications.

1575-37-7, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., Related Products of 1575-37-7

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Quality Control of 629-04-9.

Venkatesham, Papisetti;Shyam, Perugu;Pooja;Chedupaka, Raju;Vedula, Rajeswar Rao research published 《 Facile One-Pot Multi-Component Synthesis, Characterization, Molecular Docking Studies, Biological Evaluation of 1,2,4-Triazolo Isoindoline-1,3-Diones and Their DFT Calculations》, the research content is summarized as follows. Alkyl/aralkyl/phenacyl thiotriazolyl isoindoline-diones I [R = CH₂C(O)Ph, CH₂C(O)(4-O₂NC₆H₄), CH₂C(O)(4-FC₆H₄), etc.; X = H, Br] were synthesized by the reaction of dipotassium cyanodithioimidocarbonate salt with hydrazine hydrate, phthalic anhydride and alkyl/aralkyl/phenacyl bromides using acetic acid and sodium acetate via a one-pot four-component synthesis. Alternatively, the same final products I were also synthesized by the reaction of dipotassium cyanodithioimidocarbonate salt with hydrazine hydrate in presence of acetic acid to gave intermediate 5-amino-4H-1,2,4-triazole-3-thiol. This intermediate 5-amino-4H-1,2,4-triazole-3-thiol was further reacted with phthalic anhydride, followed by a reaction with alkyl/aralkyl/phenacyl bromides to gave the title compounds I in a two-step process. All the newly synthesized compounds were characterized by their spectral studies (FTIR, ¹H-NMR, ¹³C-NMR, Mass). Further, the synthesized compounds I were screened for their in-vitro anticancer activity. Compounds, I showed good cytotoxic assay against Hela cancer cell lines. Furthermore, compounds I were subjected to their docking anal. and DFT calculations

Quality Control of 629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane, HPLC of Formula: 629-04-9

Vereshchagin, A. N.;Minaeva, A. P.;Egorov, M. P. research published 《 Synthesis and antibacterial activity of new tetrakisquaternary ammonium compounds based on pentaerythritol and 3-hydroxypyridine》, the research content is summarized as follows. Tetrakisquaternary ammonium compounds based on pentaerythritol I (n = 7, 8, 9, 10, 11, 12) were synthesized for the first time. Bacteriostatic effect of the obtained compounds I was evaluated towards opportunistic gram-pos. Methicillin-resistant Staphylococcus aureus (strain ATCC 25923), gram-neg. Escherichia coli (ATCC 25922), and Pseudomonas aeruginosa (ATCC 27853). The activity of reported salts I was evaluated competitively with that of known antiseptics, Octenidine Dihydrochloride and Chlorhexidine Digluconate. The effect of length of the alkyl substituent in the salts I on their biol. activity was established. These new compounds I are based on available pentaerythritol and 3-hydroxypyridine.

HPLC of Formula: 629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine, Category: bromides-buliding-blocks

Verma, Shruti;Kujur, Shelly;Sharma, Richa;Pathak, Devendra D. research published 《 Cucurbit[6]uril-Supported Fe₃O₄ Magnetic Nanoparticles Catalyzed Green and Sustainable Synthesis of 2-Substituted Benzimidazoles via Acceptorless Dehydrogenative Coupling》, the research content is summarized as follows. A new composite, cucurbit[6]uril (CB[6])-supported magnetic nanoparticles, Fe₃O₄-CB[6], was synthesized via a co-precipitation method in air and fully characterized by Fourier transform IR spectroscopy, powder X-ray diffraction, XPS, field-emission SEM, high-resolution transmission electron microscopy, energy-dispersive X-ray spectroscopy, thermogravimetric anal., inductively coupled plasma-mass spectrometry, and vibrating sample magnetometry techniques. It has been found to be a highly efficient, economic, and sustainable heterogeneous catalyst and has been employed for the first time for the synthesis of a series of biol. important 2-substituted benzimidazoles from various benzyl alcs. and 1,2-diaminobenzenes under solvent-free conditions via acceptorless dehydrogenative coupling to afford the corresponding products in good to excellent yields (68-94%). The magnetic nature of the nanocomposite facilitates the facile recovery of the catalyst from the reaction mixture by an external magnet. The catalyst can be reused up to five times with negligible loss in its catalytic activity. All the isolated products were characterized by ¹H and ¹³C{¹H} NMR spectroscopy.

1575-37-7, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary