Tag: M.W=150-200

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 4897-84-1, formula is C5H9BrO2, Name is Methyl 4-bromobutanoate. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. HPLC of Formula: 4897-84-1.

Trivedi, Prakruti;Adhikari, Nilanjan;Amin, Sk. Abdul;Bobde, Yamini;Ganesh, Routholla;Jha, Tarun;Ghosh, Balaram research published 《 Design, synthesis, biological evaluation and molecular docking study of arylcarboxamido piperidine and piperazine-based hydroxamates as potential HDAC8 inhibitors with promising anticancer activity》, the research content is summarized as follows. Some new hydroxamate derivatives with alkylpiperidine and alkylpiperazine linker moieties were designed, synthesized and biol. evaluated. All these compounds were effective HDAC8 inhibitors comprising more or less similar cytotoxic potential against different cancer cell lines. It was observed that the piperazine scaffold containing compound was more active than the compound with piperidine scaffold for exerting HDAC8 inhibitory activity. Moreover, the 4-quinolyl cap group was better than the biphenyl group which was better than the benzyl group for producing higher HDAC8 inhibition as well as cytotoxicity. These compounds displayed selective HDAC8 inhibition over HDAC3. Moreover, these compounds showed an increased caspase3/7 activity suggesting their anticancer potential through modulation of apoptotic pathways. Mol. docking study with three potent compounds was performed with both HDAC3 and HDAC8 enzymes to understand the selectivity profile of these compounds Compound containing 4-quinolyl cap group with alkyl piperazinyl urea linker moiety was emerged out as the lead mol. that may be further modified to design more effective and selective HDAC8 inhibitors in future.

HPLC of Formula: 4897-84-1, Methyl 4-bromobutyrate,also as known as 4-Bromobutyric acid methyl ester, is a useful research compound. Its molecular formula is C5H9BrO2 and its molecular weight is 181.03 g/mol. The purity is usually 95%.
4-Bromobutyric acid methyl ester is a synthetic compound that can be used to inhibit the activity of the G1 phase cyclin-dependent kinases. It has been shown to inhibit protein synthesis by alkylating the amino groups of proteins and fatty acids. 4-Bromobutyric acid methyl ester also inhibits the growth of cancer cell lines, such as renal carcinoma cells. The mechanism of action for this drug is not well understood, but it may be due to its ability to bind with monoclonal antibodies and enter kidney cells by passive diffusion., 4897-84-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 4897-84-1, formula is C5H9BrO2, The most pervasive is the naturally produced bromomethane. Product Details of C5H9BrO2

Trukhin, D. V.;Rogozhnikova, O. Yu.;Troitskaya, T. I.;Kuzhelev, A. A.;Amosov, E. V.;Halpern, H. J.;Koval’, V. V.;Tormyshev, V. M. research published 《 New Spin Probes: Tri- and Hexacationic Derivatives of Stable Tetrathiatriarylmethyl Radicals》, the research content is summarized as follows. The reaction of Finland trityl with tertiary aliphatic alcs. containing a terminal tertiary amino group, followed by quaternization of the amino groups, afforded new highly polar tri- and hexacationic derivatives The obtained compounds were characterized by a sharp singlet signal in the EPR spectrum and were soluble in water over a wide pH range.

4897-84-1, Methyl 4-bromobutyrate,also as known as 4-Bromobutyric acid methyl ester, is a useful research compound. Its molecular formula is C5H9BrO2 and its molecular weight is 181.03 g/mol. The purity is usually 95%.
4-Bromobutyric acid methyl ester is a synthetic compound that can be used to inhibit the activity of the G1 phase cyclin-dependent kinases. It has been shown to inhibit protein synthesis by alkylating the amino groups of proteins and fatty acids. 4-Bromobutyric acid methyl ester also inhibits the growth of cancer cell lines, such as renal carcinoma cells. The mechanism of action for this drug is not well understood, but it may be due to its ability to bind with monoclonal antibodies and enter kidney cells by passive diffusion., Product Details of C5H9BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Recommanded Product: 6-Bromohexanoic acid.

Tsyganov, Dmitry V.;Samet, Alexander V.;Silyanova, Eugenia A.;Ushkarov, Vladimir I.;Varakutin, Alexander E.;Chernysheva, Natalia B.;Chuprov-Netochin, Roman N.;Khomutov, Andrey A.;Volkova, Anna S.;Leonov, Sergey V.;Semenova, Marina N.;Semenov, Victor V. research published 《 Synthesis and Antiproliferative Activity of Triphenylphosphonium Derivatives of Natural Allylpolyalkoxybenzenes》, the research content is summarized as follows. Derivatives of natural allylpolyalkoxybenzenes conjugated to triphenylphosphonium (TPP) cations by aliphatic linkers of three, six, seven, and eight atoms were synthesized to examine the role of the polyalkoxybenzene pharmacophore, TPP fragment, and linker length in antiproliferative activities. The key synthetic procedures included (i) hydroboration-oxidation of apiol, dillapiol, myristicin, and allyltetramethoxybenzene; (ii) acylation of polyalkoxybenzyl alcs. or amines; and (iii) condensation of polyalkoxybenzaldehydes followed by hydrogenation and cyclopropyl-homoallyl rearrangement. The targeted TPP conjugates as well as the starting allylbenzenes, the corresponding alkylpolyalkoxybenzenes, and the resp. alkyl-TPP salts were evaluated for cytotoxicity in a panel of human cancer cell lines using MTT and Click-iT-EdU assays and in a sea urchin embryo model. The linker of three carbon atoms was identified as favorable for selective cancer cell growth inhibition. Although the propyl-TPP salt was cytotoxic at low micromolar concentrations, the introduction of a polyalkoxybenzene moiety significantly potentiated inhibition of both cell growth and de novo DNA synthesis in several human cancer cell lines, HST-116 colon cancer, A375 melanoma, PC-3 prostate cancer, and T-47D breast carcinoma cells, while it failed to produce any developmental abnormalities in the sea urchin embryos.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., Recommanded Product: 6-Bromohexanoic acid

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane, Quality Control of 629-04-9

Tang, Bo;Zhang, Xin;Geng, Lina;Sun, Liquan;Luo, Aiqin research published 《 A chiral metal-organic cage used as the stationary phase for gas chromatography separations》, the research content is summarized as follows. Chiral metal-organic cages (MOCs) are a new type of porous materials with unique mol. recognition ability, which have received research attention as a chiral stationary phase (CSP) for gas chromatog. (GC). Herein, we report the detailed investigation of a chiral MOC ([Cu₁₂(L_PA)₁₂(H₂O)₁₂], PA = L-phenylalanine, MOC-PA) as a novel stationary phase for GC separations The MOC-PA capillary column exhibited a high-resolution performance for a wide range of analytes, including n-alkanes, n-alcs., esters, aromatic compounds and the Grob mixture, positional isomers and racemates. In particular, MOC-PA coated column displayed good resolution and performance for amino acid derivatives Moreover, the MOC-PA column showed excellent separation repeatability and reproducibility. The relative standard deviation (RSD) values for the retention times were in the range of 0.16-0.30% for run to run (n = 3), 0.31-0.77% for day-to-day (n = 3), and 3.6-4.7% for column-to-column (n = 3), resp. The exptl. results showed that MOC-PA had great potential as a GC stationary phase.

629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., Quality Control of 629-04-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Organobromine compounds have fallen under increased scrutiny for their environmental impact., HPLC of Formula: 4224-70-8.

Tang, Kai-Wei;Hsu, Wen-Li;Chen, Cheng-Ru;Tsai, Ming-Hsien;Yen, Chia-Jung;Tseng, Chih-Hua research published 《 Discovery of triazolyl thalidomide derivatives as anti-fibrosis agents》, the research content is summarized as follows. Fibrosis with excessive accumulation of extracellular matrix (ECM) often causes progressive organ dysfunction and results in many inflammatory and metabolic diseases, including systemic sclerosis, pulmonary fibrosis, advanced liver disease and advanced kidney disease. The store-operated calcium entry (SOCE) pathway and the related signaling pathway were both found to be the important routes for fibrogenesis. Our aim in this study was to discover novel compounds to inhibit fibrogenesis. A number of triazolyl thalidomide derivatives were synthesized and evaluated for their anti-fibrosis activities. Compounds inhibited intracellular Ca²⁺ activation and showed no cytotoxicity. Among them, 6-{4-[(3-(1,3-dioxoisoindolin-2-yl)-2,6-dioxopiperidin-1-yl)methyl]-1H-1,2,3-triazol-1-yl}hexanoic acid ( I ) with the most potent inhibitory effect was chosen for further examination The results revealed that compound I, a SOCE inhibitor, reversed the migratory ability of TGF-β1-induced myofibroblasts, dedifferentiated myofibroblasts to fibroblasts due to cytoskeleton remodeling, and restrained myofibroblast activation by targeting Orai1 and TGF-β1/SMAD2/3 signaling pathways. The in silico study indicated that compound I, with the appropriate lipophilic carbon chain and carboxylic acid, showed a good drug-likeness model score. Conclusively, the SOCE inhibitor, compound I, is used as a promising lead compound for the development of a new treatment for fibrosis.

HPLC of Formula: 4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Related Products of 629-04-9.

Tang, Min-Min;Kanagaraj, Kuppusamy;Rebek, Julius Jr.;Yu, Yang research published 《 Role of Rim Functions in Recognition and Selectivity of Small-Molecule Guests in Water-Soluble Cavitand Hosts》, the research content is summarized as follows. Groups on the upper rim of cavitands can play major roles in the recognition of small mols. Water-soluble deep cavitands 1, 2 or 3 bearing the walls upper rim of imidazole, urea, and Me urea, resp., were synthesized and characterized as hosts of small-mol. guests. The vase forms of 1 or 2 are stabilized through H-bonding to solvent water mols. between adjacent walls. Various small alkyl organic mols. – alcs., halides, cycloalkane derivatives and heterocycles – are efficiently bound in 1. For n-alcs. (C5 to C12), the -OH end is fixed at the upper rim and the alkyl parts are in the hydrophobic cavity. The longer alc. guests (C7-C12) show coiling. Cycloalkane guests rotate rapidly on all 3 axes within the host cavity, while heterocycles show orientations placing their heteroatoms near the cavitand rim. Competition studies between alkyl chlorides, bromides and iodides showed preference for binding of iodides in 1. Competition between cavitands for hexyl halide guests halide showed the order 2>1>3.

Related Products of 629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Electric Literature of 4224-70-8.

Tang, Qun;Xie, Yu;Liu, Yongpeng;Zheng, Lifang research published 《 Synthesis of mitochondria-targeted menadione cation derivatives: Inhibiting mitochondrial thioredoxin reductase (TrxR2) and inducing apoptosis in MGC-803 cells》, the research content is summarized as follows. Menadione (VK3) is used as a powerful inducer of cellular reactive oxygen species (ROS) for many years and displays high anti-cancer activities in vivo. Recently, the development of mitochondria-targeted drugs has been more and more appreciated. Here, thirteen derivatives of VK3, I [R¹ = H, Me, MeO, R² = pyridinium, quinolinium, triphenylphosphonium, n = 9, 6, 4], were synthesized, which could localize in mitochondria by the triphenylphosphonium (TPP) cation or the nitrogen-based cation. The results of cytotoxicity from six human cancer cell lines showed that the targeted compounds I displayed higher activity than VK3 with the average IC₅₀ value around 1μM. The results of cytotoxicity indicated that the substituents on C-2, the linear alkyl chains on C-3 and the cation moiety all could affect the cytotoxicity. The mechanistic studies showed that five representative compounds, I [R¹ = Me, R² = triphenylphosphonium, n = 9; R¹ = MeO, R² = triphenylphosphonium, n = 9; R¹ = Me, R² = pyridinium, n = 9; R¹ = Me, R² = quinolinium, n = 9; R¹ = Me, R² = triphenylphosphonium, n = 4], could localize in cellular mitochondria, elicit ROS burst and collapse mitochondrial membrane potential (ΔΨ_m), leading to cytochrome C release and apoptosis in MGC-803 cells. Particularly, they could obviously inhibit mitochondrial thioredoxin reductase TrxR2 expression, thus leading to aggravate cellular oxidative stress.

Electric Literature of 4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate, Formula: C5H7BrO3

Tang, Shi;Ding, Shumin;Li, Dan;Li, Lianjie;Zhao, Haixia;Chai, Minxue;Wang, Jian research published 《 Palladium-catalysed imidoylative spirocyclization of 3-(2-isocyanoethyl)indoles》, the research content is summarized as follows. A palladium-catalyzed construction of spiroindolines through dearomative spirocyclization of 3-(2-isocyanoethyl)indoles was developed. 2′-Aryl-, vinyl-, and alkyl-substituted spiroindolines were accessed under mild conditions with excellent functional group tolerance. C1-tethered oxindole- and indole-spiroindoline bisheterocycles were generated in high yields via alkene/allene insertion and an imidoylative spirocyclization cascade. Addnl., a tandem dearomatization of two different indoles was realized with N-(2-bromobenzoyl)indoles as the electrophilic coupling partner of 3-(2-isocyanoethyl)indoles, affording polyindoline – spiroindoline bisheterocyclic scaffolds conveniently. Under the catalysis of Pd(OAc)₂ and a spinol-derived phosphoramidite ligand, chiral spiroindolines were successfully accessed with up to 95% yield and 85% ee.

70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., Formula: C5H7BrO3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Computed Properties of 4224-70-8.

Tang, Zi-Liang;Ouyang, Xuan-Hui;Song, Ren-Jie;Li, Jin-Heng research published 《 Decarboxylative C(sp³)-N Cross-Coupling of Diacyl Peroxides with Nitrogen Nucleophiles》, the research content is summarized as follows. A new radical-mediated decarboxylative C(sp³)-N cross-coupling of diacyl peroxides with nitrogen nucleophiles has been disclosed. The primary and secondary alkyl radicals derived from corresponding diacyl peroxides were generated by copper catalysis or by merging copper catalysis and photoredox catalysis, resp. Various N-alkyl nitrogen nucleophiles, including indazoles, triazoles, indoles, purine, carbazole, anilines, and sulfonamide, were provided with a broad substrate scope and good functional group tolerance.

Computed Properties of 4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid, Application of C6H11BrO2

Tao, Lei;Yang, Wen;Zhao, Wanxiang research published 《 Synthesis of Carboxylic Acids, Esters, and Amides from 1,1-Dibromoalkenes via Oxidation of Alkynyl Boronate Intermediates》, the research content is summarized as follows. An efficient and practical method for the synthesis of carboxylic acids RCH₂COOH (R = cyclohexyl, biphenyl-4-yl, thiophen-2-yl, etc.), esters RCH₂C(O)OR¹ (R¹ = Me, Bn, cyclopropylmethyl, etc.), and amides RCH₂C(O)NR²R³ [R² = H, Et, i-Pr, Cy, Bn; R³ = n-Bu, cycloproyl, t-Bu, Et, i-Pr, Cy, Bn; R²R³ = -(CH₂)₂O(CH₂)₂-] from 1,1-dibromoalkenes RCH=CBr₂Me has been developed. The reactions proceed through a key process, the C(sp)-B bond oxidation of alkynyl boronate intermediates with Oxone. This protocol features broad substrate scope, good efficiency, and good functional group compatibility. Moreover, the synthetic practicability was demonstrated by easy gram-scale preparation and the synthesis of drug mols., e.g., diclofenac.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., Application of C6H11BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary