Tag: M.W=150-200

Fu, Jie published the artcileUltralow-cost portable device for cesium detection via perovskite fluorescence, Recommanded Product: 1-Bromooctane, the publication is Journal of Hazardous Materials (2022), 127981, database is CAplus and MEDLINE.

Public anxiety and concern from cesium pollution in oceans have been back on the agenda since tons of nuclear waste water were announced to be poured into oceans. Cesium ion can easily enter organisms and bioaccumulate in animals and plants, thus its harm is chronic to humans through food chains. Here we showed a kind of hybrid ionic liquid membrane (HILM) for detection of cesium ion in seawater through CsPbBr₃ perovskite fluorescence. With sustainability in mind, HILM was built frugally. The lowest cost of HILM is below 3 cents per piece. The HILM can detect cesium ion quickly with eye-readable fluorescence signal. Ultracheap, portable, easy-to-use on-site detection device could offer benefit for personal security and applications in environment science and ecol. in the future decades.

Journal of Hazardous Materials published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H17Br, Recommanded Product: 1-Bromooctane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Coombs, John R. published the artcileEnantiomerically Enriched Tris(boronates): Readily Accessible Conjunctive Reagents for Asymmetric Synthesis, SDS of cas: 81216-14-0, the publication is Journal of the American Chemical Society (2014), 136(46), 16140-16143, database is CAplus and MEDLINE.

The catalytic enantioselective diboration of vinyl boronate esters furnishes chiral tris(boronates) in a selective fashion. Subsequent deborylative alkylation occurs in a diastereoselective fashion, both for intermol. and intramol. processes.

Journal of the American Chemical Society published new progress about 81216-14-0. 81216-14-0 belongs to bromides-buliding-blocks, auxiliary class Linker,PROTAC Linker, name is 7-Bromohept-1-yne, and the molecular formula is C7H11Br, SDS of cas: 81216-14-0.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Fujimoto, Kazuki published the artcileStructure-Based Approaches to Improving Selectivity through Utilizing Explicit Water Molecules: Discovery of Selective β-Secretase (BACE1) Inhibitors over BACE2, Computed Properties of 401-55-8, the publication is Journal of Medicinal Chemistry (2021), 64(6), 3075-3085, database is CAplus and MEDLINE.

BACE1 is an attractive target for disease-modifying treatment of Alzheimer′s disease. BACE2, having high homol. around the catalytic site, poses a critical challenge to identifying selective BACE1 inhibitors. Recent evidence indicated that BACE2 has various roles in peripheral tissues and the brain, and therefore, the chronic use of nonselective inhibitors may cause side effects derived from BACE2 inhibition. Crystallog. anal. of the nonselective inhibitor verubecestat identified explicit water mols. with different levels of free energy in the S2′ pocket. Structure-based design targeting them enabled the identification of propynyl oxazine 3 with improved selectivity. Further optimization efforts led to the discovery of compound 6 with high selectivity. The cocrystal structures of 7, a close analog of 6, bound to BACE1 and BACE2 confirmed that one of the explicit water mols. is displaced by the propynyl group, suggesting that the difference in the relative water displacement cost may contribute to the improved selectivity.

Journal of Medicinal Chemistry published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C4H6BrFO2, Computed Properties of 401-55-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Huang, Qi published the artcileInexpensive Radical Methylation and Related Alkylations of Heteroarenes, SDS of cas: 401-55-8, the publication is Organic Letters (2018), 20(5), 1413-1416, database is CAplus and MEDLINE.

A simple method for the introduction of a Me and higher aliphatic group to various heteroarenes using very inexpensive reagents is described. It is based on the radical addition of a carboxylic xanthate followed by decarboxylation. Depending on the heteroarene structure, the decarboxylation can be spontaneous or induced by heating in N,N-dimethylacetamide or N-Me pyrrolidone in a microwave oven.

Organic Letters published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C4H6BrFO2, SDS of cas: 401-55-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Nova, Nabila Nabi published the artcileDirect laser writing of graphitic carbon from liquid precursors, Application In Synthesis of 111-83-1, the publication is Chemistry of Materials (2022), 34(10), 4602-4612, database is CAplus.

One-step synthesis and micropatterning of different types of carbon nanomaterials, such as amorphous carbon or three-dimensional graphene which have versatile electrochem., thermal, and mech. properties, are advantageous for the fabrication of microelectronics, sensors, and wearable devices. Here, we report a direct laser writing method to simultaneously synthesize and pattern graphitic carbon from liquid organic precursors. We have tested a wide range of liquid organic precursors and identified the chem. characteristics that are beneficial for successful laser-induced solvothermal deposition. The laser-deposited carbon exhibits a paracryst.-to-polycrystalline structure and has elec. resistivities on the order of 10^-3 to 10^-4 Ω m which is tunable through variations in the laser power. Such properties of the laser-deposited carbon, coupled with the ability to direct-write custom patterns with microscale resolution, make these carbon materials exciting candidates for use in applications such as energy storage and sensing.

Chemistry of Materials published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H17Br, Application In Synthesis of 111-83-1.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Jing, Liling published the artcileSynthesis and carbene-insertion preparation of hydrophobic natural polymer materials for rapid and efficient oil/water separation, Category: bromides-buliding-blocks, the publication is Applied Surface Science (2022), 152394, database is CAplus.

In response to frequent oil spills and increasing discharges of oily wastewater, a variety of materials and methods have been developed to treat with oil-water mixtures In this paper, a simple and versatile method to modify a broad spectrum of natural polymer surfaces (wood aerogel, pulpboard, filter paper, cotton cloth, electrospinning gelatin film, ultrafine polypropylene fiber) was reported. This modification was based on aryl diazo compounds with hydrophobic functional groups as precursors, which were thermally activated to generate highly active carbene intermediates and induce the X-H (X = O, C,…) insertion reaction on the surface of substrates. The success of surface modification was demonstrated by the irreversible changes of the surface properties and the application on multi-behavior oil/water separation Moreover, according to the Owens-Wendt-Rabel-Kaelble method, the influence of the dispersion force and the polar force on various material surfaces was given to explore the separation mechanism. This one-step modification provides a facile and efficient strategy to achieve renewable, biodegradable, and environmentally friendly materials and surfaces with low surface energy, which offers considerable potential applications on disposal of oil pollution in the environment.

Applied Surface Science published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H17Br, Category: bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Xu, Haowei published the artcileSynthesis of secondary amines with long chains containing ether bonds, Synthetic Route of 111-83-1, the publication is Synlett (2022), 33(11), 1059-1064, database is CAplus.

A novel class of secondary amines with long chains containing ether bonds were synthesized by three-step protection-etherification-deprotection process from diethanolamine. The optimum reaction conditions were examined This method has the advantages of simplicity, low cost and high yield. Furthermore, some new downstream products (diglycolamides) were prepared from the ether-containing long-chain secondary amines as reactants and their loading capacities in extractions of several metal ions were evaluated.

Synlett published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H6BrF3S, Synthetic Route of 111-83-1.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Guan, Weijiang published the artcileDesign of a Temperature-Independent Luminescent Probe for Visualization of Ice-to-Liquid Transition at -129°C, Safety of 1-Bromooctane, the publication is Journal of Physical Chemistry C (2022), 126(17), 7556-7563, database is CAplus.

The temperature-dependent nature and intense emission in solution of fluorescence mols. prevent them from visualizing various processes accompanying temperature changes (e.g., the liquid-ice transition at ultralow temperatures). To overcome the intrinsic difficulty, we synthesized a custom-designed fluorescent probe to exhibit the temperature-independent negligible fluorescence in the solution state but emit bright light in the icing state. The ice-to-liquid transition of four hydrocarbons, whose f.ps. are between -27 and -129°C, can be sensitively visualized using the proposed temperature-independent fluorescent probe. More interestingly, we have built a homemade platform to enable the real-time imaging of the f.ps. of these four hydrocarbons within 3 min. For the first time, we designed a liquid-ice transition-sensitive probe at ultralow temperatures, different from the conventional temperature-dependent systems. This success will not only help to gain insights into the icing mechanisms but may also contribute to the development of portable visualization devices for monitoring phase transition.

Journal of Physical Chemistry C published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H17Br, Safety of 1-Bromooctane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Zhang, Yan published the artcileCopper-Catalyzed Radical Cascade Difluoromethylation/Cyclization of 2-(3-Arylpropioloyl)benzaldehydes: A Route to Difluoromethylated Naphthoquinones, Application of Ethylbromofluoroacetate, the publication is Journal of Organic Chemistry (2017), 82(13), 6811-6818, database is CAplus and MEDLINE.

A novel copper-catalyzed cascade difluoromethylation/cyclization of 2-(3-arylpropioloyl)benzaldehydes has been developed. This method affords an efficient and straightforward access to structurally diverse difluoromethylated naphthoquinones in one pot, starting from readily available starting materials. The reaction represents the first trans-acyldifluoromethylation of internal alkynes, which features aldehydes as acceptors for the addition of alkenyl radicals. Furthermore, this protocol can also access monofluoromethylated naphthoquinones and difluoromethylated indanones with the same reaction conditions.

Journal of Organic Chemistry published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C15H10O2, Application of Ethylbromofluoroacetate.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Kounde, Cyrille S. published the artcileDiscovery of 2-oxopiperazine dengue inhibitors by scaffold morphing of a phenotypic high-throughput screening hit, Synthetic Route of 56970-78-6, the publication is Bioorganic & Medicinal Chemistry Letters (2017), 27(6), 1385-1389, database is CAplus and MEDLINE.

A series of 2-oxopiperazine derivatives were designed from the pyrrolopiperazinone cell-based screening hit 4 (I) as a dengue virus inhibitor. Systematic investigation of the structure-activity relationship (SAR) around the piperazinone ring led to the identification of compound (S)-29, which exhibited potent anti-dengue activity in the cell-based assay across all four dengue serotypes with EC₅₀ < 0.1 μM. Cross-resistant anal. confirmed that the virus NS4B protein remained the target of the new oxopiperazine analogs obtained via scaffold morphing from the HTS hit 4.

Bioorganic & Medicinal Chemistry Letters published new progress about 56970-78-6. 56970-78-6 belongs to bromides-buliding-blocks, auxiliary class Bromide,Carboxylic acid,Aliphatic hydrocarbon chain,Inhibitor, name is 3-Bromo-2-methylpropanoic acid, and the molecular formula is C4H7BrO2, Synthetic Route of 56970-78-6.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary