Tag: M.W=150-200

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Organobromine compounds have fallen under increased scrutiny for their environmental impact., HPLC of Formula: 70-23-5.

Piltan, Mohammad research published 《 Syntheses of Novel Tetrasubstituted Thiophenes from Benzene-1,2-Diamines, Ethyl Bromopyruvate, Malononitrile, and Aryl Isothiocyanates》, the research content is summarized as follows. Synthesis of amino(oxo-dihydroquinoxalinyl)(phenylamino)thiophene-carbonitrile derivatives I [R = H, Me, Cl; R¹ = 2-MeOC₆H₄, 4-NO₂C₆H₄, Et, Ph] was reported via sequential base mediated condensation of malononitrile with aryl isothiocyanates followed by S-alkylation with 3-(bromomethyl)quinoxalin-2(1H)-one compounds and concurrent intramol. enamine type condensation of S-alkylated compounds in excellent yields.

70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., HPLC of Formula: 70-23-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Synthetic Route of 70-23-5.

Pokhodylo, N. T.;Tupychak, M. A.;Obushak, M. D. research published 《 Metal-Free Synthesis of 1,5-Disubstituted 1,2,3-Triazoles》, the research content is summarized as follows. The main synthetic approaches to 1,5-disubstituted 1,2,3-triazoles were considered. It was shown that the cycloaddition of aryl azides to phosphorus keto ylides provide a convenient method for the synthesis of 1,5-disubstituted 1,2,3-triazoles, especially in cases, where the target compounds contain hydrophilic substituents. An alternative approach to the synthesis of 1,5-disubstituted 1,2,3-triazoles by decarboxylation of 1H-1,2,3-triazole-4-carboxylic acids is proposed. New 1,5-disubstituted 1,2,3-triazoles, 1H-1,2,3-triazolyl-1-benzoic acids, 1H-1,2,3-triazole-5-carboxylic acids, and 1H-1,2,3-triazole-5-acetic acids are convenient precursors for further modification.

70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., Synthetic Route of 70-23-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 629-04-9, formula is C7H15Br, The most pervasive is the naturally produced bromomethane. Application of C7H15Br

Potaniec, Bartlomiej;Zdonczyk, Maria;Cybinska, Joanna research published 《 Controlled Synthesis of Luminescent Xanthene Dyes and Use of Ionic Liquid in Thermochromic Reaction》, the research content is summarized as follows. In this study, we demonstrate six novel xanthene derivatives and their spectroscopic and chem. properties. The presented synthesis examination allowed us to obtain two different compounds during one step, with open and closed lactone rings substituted with different length alkyl chains. Increasing the reaction efficiency to 77% was obtained using the microwave-assisted method. Moreover, the modification of O-alkylation synthesis in an ecofriendly way using a ball mill led to achieving exclusively one opened ring product. All of the synthesized compounds showed different spectroscopic behaviors in comparison with the different organic dyes; the typical concentration quenching of luminescence was not observed The relationship between the length of the alkyl chain and the time of luminescence decay is presented. Synthesized closed forms of dyes turned out to be promising leuco dyes. For the first time, an ionic liquid was used as a developer of synthesized xanthene derivatives (as leuco dyes), which led to obtaining an irreversible thermochromic marker.

629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., Application of C7H15Br

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate, Reference of 70-23-5

Pragathi, Y. J.;Veronica, D.;Rao, M. V. Basaveswara;Raju, R. R. research published 《 Design, Synthesis, and Anticancer Activity of 1,3,4-Oxadiazole Incorporated 5-(Pyrimidin-5-yl)benzo[d]oxazole Derivatives》, the research content is summarized as follows. A novel series of 5-(pyrimidin-5-yl)benzo[d]oxazole derivatives I [R = H, 4-MeO, 3,5-di-O₂N, etc.] was synthesized and the chem. structures of products were determined by ¹H and ¹³C NMR, and mass spectra. The products I were tested for their anticancer activity against a panel of human cancer cell lines such as MCF-7 (breast cancer), A549 (lung cancer), Colo-205 (colon cancer) and A2780 (ovarian cancer) using MTT assay. Some tested compounds were demonstrated significant anticancer activity higher than that of the reference drug.

Reference of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Related Products of 70-23-5.

Priestley, E. Scott;Banville, Jacques;Deon, Daniel;Dube, Laurence;Gagnon, Marc;Guy, Julia;Lapointe, Philippe;Lavallee, Jean-Francois;Martel, Alain;Plamondon, Serge;Remillard, Roger;Ruediger, Edward;Tremblay, Francois;Posy, Shana L.;Guarino, Victor R.;Richter, Jeremy M.;Li, Jianqing;Gupta, Anuradha;Vetrichelvan, Muthalagu;Balapragalathan, T. J.;Mathur, Arvind;Hua, Ji;Callejo, Mario;Guay, Jocelyne;Sum, Chi Shing;Cvijic, Mary Ellen;Watson, Carol;Wong, Pancras;Yang, Jing;Bouvier, Michel;Gordon, David A.;Wexler, Ruth R.;Marinier, Anne research published 《 Discovery of Two Novel Antiplatelet Clinical Candidates (BMS-986120 and BMS-986141) That Antagonize Protease-Activated Receptor 4》, the research content is summarized as follows. Herein, the optimization of a series of imidazothiadiazole PAR4 antagonists to a first-in-class clin. candidate, BMS-986120 I, and a backup clin. candidate, BMS-986141 II was described. Both compounds demonstrated excellent antithrombotic efficacy and minimal bleeding time prolongation in monkey models relative to the clin. important antiplatelet agent clopidogrel and provide a potential opportunity to improve the standard of care in the treatment of arterial thrombosis.

Related Products of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 629-04-9, formula is C7H15Br, The most pervasive is the naturally produced bromomethane. SDS of cas: 629-04-9

Patberg, Marius;Isaak, Andreas;Fuesser, Friederike;Ortiz Zacarias, Natalia V.;Vinnenberg, Laura;Schulte, Janine;Michetti, Lucia;Grey, Lucie;van der Horst, Cas;Hundehege, Petra;Koch, Oliver;Heitman, Laura H.;Budde, Thomas;Junker, Anna research published 《 Piperazine squaric acid diamides, a novel class of allosteric P2X7 receptor antagonists》, the research content is summarized as follows. The P2X7 receptor (P2X7R) stands out among the purinergic receptors due to its strong involvement in the regulation of tumor growth and metastasis formation as well as in innate immune responses and afferent signal transmission. Numerous studies have pointed out the beneficial effects of P2X7R antagonism for the treatment of a variety of cancer types, inflammatory diseases, and chronic pain. Herein we describe the development of novel P2X7R antagonists, incorporating piperazine squaric diamides as a central element. Besides improving the antagonists potency from pIC50 values of 5.7-7.6, ADME properties (logD7.4 value, plasma protein binding, in vitro metabolic stability) of the generated compounds were investigated and optimized to provide novel P2X7R antagonists with drug-like properties. Furthermore, docking studies revealed the antagonists binding to the allosteric binding pocket in two distinct binding poses, depending on the substitution of the central piperazine moiety.

SDS of cas: 629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Name: 1-Bromoheptane.

Patil, Sushil M.;Gupta, Santosh K.;Goswami, Dibakar;Ghosh, Ayan;Tyagi, Mohit;Dhotare, Bhaskar B.;Ghanty, Tapan K.;Gupta, Ruma research published 《 Dopant-Free, Blue-Light-Emitting, Hydrophobic Deep Eutectic Solvent and Its Application as a Liquid Scintillator》, the research content is summarized as follows. Rare-earth-free, environmentally benign liquid luminogen are scarce. Herein, we report for the first time a deep eutectic solvent as a blue-emitting liquid luminogen with a quantum yield of ∼23%. DFT calculations deciphered the origin of blue emission. Its potential as a liquid scintillator was further demonstrated with γ-emitting radioactive sources.

Name: 1-Bromoheptane, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Organic compounds having carbon bonded to bromine are called organic bromides. Quality Control of 70-23-5.

Paul, Rakesh;Dutta, Debasish;Paul, Raj;Dash, Jyotirmayee research published 《 Target-directed azide-alkyne cycloaddition for assembling HIV-1 TAR RNA binding ligands》, the research content is summarized as follows. The highly conserved HIV-1 transactivation response element (TAR) binds to the trans-activator protein Tat and facilitates viral replication in its latent state. The inhibition of Tat-TAR interactions by selectively targeting TAR RNA has been used as a strategy to develop potent antiviral agents. Therefore, HIV-1 TAR RNA represents a paradigmatic system for therapeutic intervention. Herein, we have employed biotin-tagged TAR RNA to assemble its own ligands from a pool of reactive azide and alkyne building blocks. To identify the binding sites and selectivity of the ligands, the in situ cycloaddition has been further performed using control nucleotide (TAR DNA and TAR RNA without bulge) templates. The hit triazole-linked thiazole peptidomimetic products have been isolated from the biotin-tagged target templates using streptavidin beads. The major triazole lead generated by the TAR RNA presumably binds in the bulge region, shows specificity for TAR RNA over TAR DNA, and inhibits Tat-TAR interactions.

70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., Quality Control of 70-23-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 5445-17-0, formula is C4H7BrO2, Name is Methyl 2-bromopropanoate. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Safety of Methyl 2-bromopropanoate.

Pavan, Paola;Lorandi, Francesca;De Bon, Francesco;Gennaro, Armando;Isse, Abdirisak A. research published 《 Enhancement of the Rate of Atom Transfer Radical Polymerization in Organic Solvents by Addition of Water: An Electrochemical Study.》, the research content is summarized as follows. Addition of water to organic solvents enhances the rate of atom transfer radical polymerization (ATRP). To understand the origin of this rate enhancement, the effects of H₂O on the redox properties of [Cu^IITPMA]²⁺ and [BrCu^IITPMA]⁺ (TPMA=tris(2-pyridylmethyl)amine), and on the ATRP equilibrium (K_ATRP) and activation rate (k_act) constants of Me 2-bromopropionate by [Cu^ITPMA]⁺ were investigated in CH₃CN, DMF and DMSO and their mixtures with Me acrylate (MA). E°s of the complexes allowed evaluation of the relative halidophilicities of [Cu^IITPMA]²⁺ and [Cu^ITPMA]⁺, K^IIBr and K^IBr, resp. K^IIBr/K^IBr dropped in pure solvents and solvent/MA mixtures when 11% (volume/volume) H₂O was added, suggesting that H₂O hampers the stability of the deactivator [BrCu^IITPMA]⁺. Conversely, both k_act and K_ATRP were enhanced by the presence of water. In solvent/MA mixtures (50/50, volume/volume), addition of 11% (volume/volume) H₂O increased K_ATRP by a factor of 2-3, which could explain the accelerating effect of H₂O on ATRP in organic solvents.

5445-17-0, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., Safety of Methyl 2-bromopropanoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. SDS of cas: 1575-37-7.

Peerzade, Nargisbano A.;Jadhav, Shravan Y.;Varpe, Bhushan D.;Kulkarni, Amol A.;Bhosale, Raghunath B. research published 《 Green Synthesis, Molecular Docking, In Silico ADME and Biological Evaluation of Methoxy Substituted 1,5-Benzodiazepines as Potential Antioxidant, Anti-Inflammatory, and Antidiabetic Agents》, the research content is summarized as follows. Present work involves the green and environmentally benign synthesis of 1,5-benzodiazepines using iodine as a catalyst and PEG-400 as a green solvent at room temperature that gives an excellent yield of products. All the synthesized compounds were screened for their anti-inflammatory, antioxidant, and antidiabetic activity. All the synthesized compounds showed excellent antioxidant activity against DPPH and H₂O₂ radicals as compared to standard ascorbic acid and even more than standard for SOR and NO radicals. Compound I showed the highest % anti-inflammatory activity i.e., among the series that was comparable to standard diclofenac sodium whereas compound II showed the highest antidiabetic activity i.e., which was found potent as compared to standard acarbose.

1575-37-7, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., SDS of cas: 1575-37-7

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary