Tag: M.W=200-250

Taniguchi, Tsuyoshi published the artcileFormal Total Synthesis of Haouamine A, Synthetic Route of 89694-44-0, the publication is Journal of Organic Chemistry (2009), 74(6), 2624-2626, database is CAplus and MEDLINE.

A synthesis of the indenotetrahydropyridine unit I of haouamine A is described. The construction of a diaryl quaternary center and tricyclic framework of this compound was achieved by an intramol. cascade Mizoroki-Heck reaction.

Journal of Organic Chemistry published new progress about 89694-44-0. 89694-44-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is 2-Bromo-5-methoxybenzene boronic acid, and the molecular formula is C15H21BO2, Synthetic Route of 89694-44-0.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Caporusso, Anna Maria published the artcileStereoselective Synthesis of Chiral 3-Aryl-1-alkynes from Bromoallenes and Heterocuprates, Synthetic Route of 69361-41-7, the publication is Journal of Organic Chemistry (2006), 71(5), 1902-1910, database is CAplus and MEDLINE.

The synthesis of racemic and chiral 3-aryl-1-alkynes HCCCR¹R²R³ (R¹ = H, Me; R² = Me, Et, Me₃C; R³ = Ph, 2-EtC₆H₄, 4-MeOC₆H₄, 1-naphthyl, etc.) via cross-coupling of 3-alkyl- and 3,3-dialkyl-1-bromo-1,2-dienes R¹R²C:C:CHBr and arylbromocuprates (R³CuBr)MgBr·LiBr was examined With phenylcopper reagents and its para-substituted derivatives, as well as with 2-naphthyl cuprates, the reaction gave 3-aryl-1-alkynes with high regioselectivity and in good yields. On the contrary, when ortho-substituted Ph reagents and 1-naphthyl cuprates were used, the regioselectivity of the process was very dependent upon the steric requirements of the alkyl substituents on the bromoallenic substrate. When the steric bulk was increased, remarkable quantities of isomeric arylallenes R¹R²C:C:CHR³ were also observed in the reaction mixtures The high 1,3-anti stereoselectivity of the coupling process allowed us to obtain enantiomerically enriched 3-aryl-1-alkynes from optically active allenic substrates, thus indicating a simple pathway toward the synthesis of quaternary stereogenic centers characterized by an aryl group. A possible cross-coupling mechanism was also suggested to explain the regio- and stereochem. data. For the preparation of ω-functionalized 3-phenyl-1-alkynes R⁴CHPhCCH [R⁴ = H₂C:CH(CH₂)₂, Me₃SiCC(CH₂)₂, HO(CH₂)₃], the reaction of 1-bromo-3-phenylpropadiene with Knochel reagents R⁵Cu(CN)ZnCl·2LiCl [R⁵ = H₂C:CH(CH₂)₂, Me₃SiCC(CH₂)₂, ClMgO(CH₂)₃] was also studied; this reaction led to the acetylenic compounds in high yields mainly when the R⁵ group on the copper reagent was primary.

Journal of Organic Chemistry published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Synthetic Route of 69361-41-7.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Tang, Luning published the artcileReductive Opening of Oxetanes Catalyzed by Frustrated Lewis Pairs: Unexpected Aryl Migration via Neighboring Group Participation, Recommanded Product: 1-Bromododecane, the publication is Organic Letters (2022), 24(17), 3259-3264, database is CAplus and MEDLINE.

B(C₆F₅)₃ was found to catalyze an unusual double reduction of oxetanes by hydrosilane with aryl migration via neighboring group participation. Control experiments suggested that the phenonium ion serves as the key intermediate. Minor modification of this protocol also led to simple hydrosilylative opening of oxetanes.

Organic Letters published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C14H10O4, Recommanded Product: 1-Bromododecane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Tzerpos, Nikolaos I. published the artcileDiphenylpyridylmethyl radicals. Part 1. Synthesis, dimerization and ENDOR spectroscopy of diphenyl(2-, 3- or 4-pyridyl)methyl radicals; bond dissociation enthalpies of their dimers, Formula: C6H12Br2, the publication is Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1995), 755-61, database is CAplus.

Ortho-ortho hydrogen van der Waals repulsions are the origin of the propeller shape of the triphenylmethyl radical and the main reason for the low bond dissociation enthalpy (BDH) of its dimer I (44.8 J mol^-1). In order to reduce these steric repulsions (eliminating some aromatic hydrogens), diphenyl(2-, 3- or 4-pyridyl)methyl radicals (e.g, II) were prepared through reductive dehalogenation of the corresponding triarylchloromethanes (e.g., III) with silver in benzene. They form α,p-dimers IV–VI exclusively through the pyridine ring. ENDOR spectroscopy shows that the structure of the radicals, does not deviate substantially from that of the parent radical, Ph₃C•. In contrast, the BDH values of the dimers (measured using ESR spectroscopy) show strengthening of the central C-C bond in IV (88.7 kJ mol^-1) and V (90.0 kJ mol^-1) and a similar value for VI (46.4 kJ mol^-1) with respect to the trityl dimer I. This is a consequence of the ground state stabilization of the dimers IV–VI due to relief of strain (elimination of ring hydrogens), whereas in the case of VI, this stabilization is probably compensated by the formation of a weaker C-N bond with respect to the C-C bond. The above dimers undergo easy 1,5-H-rearrangement, autocatalyzed by the basic pyridyl groups themselves.

Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry published new progress about 594-81-0. 594-81-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 2,3-Dibromo-2,3-dimethylbutane, and the molecular formula is C11H24O3, Formula: C6H12Br2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Nova, Nabila Nabi published the artcileDirect laser writing of graphitic carbon from liquid precursors, Application of 1-Bromododecane, the publication is Chemistry of Materials (2022), 34(10), 4602-4612, database is CAplus.

One-step synthesis and micropatterning of different types of carbon nanomaterials, such as amorphous carbon or three-dimensional graphene which have versatile electrochem., thermal, and mech. properties, are advantageous for the fabrication of microelectronics, sensors, and wearable devices. Here, we report a direct laser writing method to simultaneously synthesize and pattern graphitic carbon from liquid organic precursors. We have tested a wide range of liquid organic precursors and identified the chem. characteristics that are beneficial for successful laser-induced solvothermal deposition. The laser-deposited carbon exhibits a paracryst.-to-polycrystalline structure and has elec. resistivities on the order of 10^-3 to 10^-4 Ω m which is tunable through variations in the laser power. Such properties of the laser-deposited carbon, coupled with the ability to direct-write custom patterns with microscale resolution, make these carbon materials exciting candidates for use in applications such as energy storage and sensing.

Chemistry of Materials published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H25Br, Application of 1-Bromododecane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Jing, Liling published the artcileSynthesis and carbene-insertion preparation of hydrophobic natural polymer materials for rapid and efficient oil/water separation, Related Products of bromides-buliding-blocks, the publication is Applied Surface Science (2022), 152394, database is CAplus.

In response to frequent oil spills and increasing discharges of oily wastewater, a variety of materials and methods have been developed to treat with oil-water mixtures In this paper, a simple and versatile method to modify a broad spectrum of natural polymer surfaces (wood aerogel, pulpboard, filter paper, cotton cloth, electrospinning gelatin film, ultrafine polypropylene fiber) was reported. This modification was based on aryl diazo compounds with hydrophobic functional groups as precursors, which were thermally activated to generate highly active carbene intermediates and induce the X-H (X = O, C,…) insertion reaction on the surface of substrates. The success of surface modification was demonstrated by the irreversible changes of the surface properties and the application on multi-behavior oil/water separation Moreover, according to the Owens-Wendt-Rabel-Kaelble method, the influence of the dispersion force and the polar force on various material surfaces was given to explore the separation mechanism. This one-step modification provides a facile and efficient strategy to achieve renewable, biodegradable, and environmentally friendly materials and surfaces with low surface energy, which offers considerable potential applications on disposal of oil pollution in the environment.

Applied Surface Science published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H25Br, Related Products of bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Xu, Haowei published the artcileSynthesis of secondary amines with long chains containing ether bonds, Product Details of C12H25Br, the publication is Synlett (2022), 33(11), 1059-1064, database is CAplus.

A novel class of secondary amines with long chains containing ether bonds were synthesized by three-step protection-etherification-deprotection process from diethanolamine. The optimum reaction conditions were examined This method has the advantages of simplicity, low cost and high yield. Furthermore, some new downstream products (diglycolamides) were prepared from the ether-containing long-chain secondary amines as reactants and their loading capacities in extractions of several metal ions were evaluated.

Synlett published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C9H5ClO2, Product Details of C12H25Br.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Gu, Yiting published the artcileDefunctionalization of sp³ C-Heteroatom and sp³ C-C Bonds Enabled by Photoexcited Triplet Ketone Catalysts, Recommanded Product: 1-Bromododecane, the publication is ACS Catalysis (2022), 12(2), 1031-1036, database is CAplus.

A general strategy for enabling a light-induced defunctionalization of sp³ C-heteroatom and sp³ C-C bonds with triplet ketone catalysts and bipyridine additives was disclosed. This protocol was characterized by its broad scope without recourse to transition metal catalysts or stoichiometric exogeneous reductants, thus offering a complementary technique for activating σ sp³ C-C(heteroatom) bonds. Preliminary mechanistic studies suggest that the presence of 2,2′-bipyridines improves the lifetime of ketyl radical intermediates.

ACS Catalysis published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H25Br, Recommanded Product: 1-Bromododecane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Luo, Yiyang published the artcileTotal Synthesis of trans-Resorcylide via Macrocyclic Stille Carbonylation, Application of (4-Bromobut-1-yn-1-yl)trimethylsilane, the publication is Journal of Antibiotics (2019), 72(6), 482-485, database is CAplus and MEDLINE.

The resorcylic macrolides are important natural products with a wide range of remarkable biol. activities. So far, most of the reported resorcylic macrolide syntheses use either macrolactonization or ring closing metathesis to build the corresponding macrocycle. In continuation of our efforts in developing novel carbonylation reactions to facilitate natural product total synthesis, we report herein a total synthesis of trans-resorcylide (I) featuring a palladium-catalyzed macrocyclic Stille carbonylation to build its 12-membered macrocycle.

Journal of Antibiotics published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Application of (4-Bromobut-1-yn-1-yl)trimethylsilane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Morimoto, Tsumoru published the artcileRh(I)-Catalyzed CO Gas-Free Carbonylative Cyclization Reactions of Alkynes with 2-Bromophenylboronic Acids Using Formaldehyde, Synthetic Route of 89694-44-0, the publication is Organic Letters (2009), 11(8), 1777-1780, database is CAplus and MEDLINE.

The rhodium(I)-catalyzed reaction of alkynes with 2-bromophenylboronic acids in the presence of paraformaldehyde resulted in a CO gas-free carbonylative cyclization, yielding indenone derivatives [RhCl(BINAP)]₂ and [RhCl(cod)]₂ were responsible for the decarbonylation of formaldehyde and the subsequent carbonylation of alkynes with 2-haloboronic acids, resp., leading to efficient whole carbonylation. Sterically bulky and electron-withdrawing groups on unsym. substituted alkynes favored the α-position of indenones.

Organic Letters published new progress about 89694-44-0. 89694-44-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is 2-Bromo-5-methoxybenzene boronic acid, and the molecular formula is C7H8BBrO3, Synthetic Route of 89694-44-0.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary