Klausfelder, Barbara team published research in Chemistry – A European Journal in | 402-49-3

402-49-3, 4-Trifluoromethylbenzyl bromide is a useful research compound. Its molecular formula is C8H6BrF3 and its molecular weight is 239.03 g/mol. The purity is usually 95%.
4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond., Quality Control of 402-49-3

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 402-49-3, formula is C8H6BrF3, The most pervasive is the naturally produced bromomethane. Quality Control of 402-49-3

Klausfelder, Barbara;Blach, Patricia;de Jonge, Niels;Kempe, Rhett research published 《 Synthesis of 3,4-Dihydro-2H-Pyrroles from Ketones, Aldehydes, and Nitro Alkanes via Hydrogenative Cyclization》, the research content is summarized as follows. Syntheses of N-heterocyclic compounds that permit a flexible introduction of various substitution patterns by using inexpensive and diversely available starting materials are highly desirable. Easy to handle and reusable catalysts based on earth-abundant metals are especially attractive for these syntheses. Author report here on the synthesis of 3,4-dihydro-2H-pyrroles via the hydrogenation and cyclization of nitro ketones. The latter are easily accessible from three components: a ketone, an aldehyde and a nitroalkane. The reaction has a broad scope and 23 of the 33 products synthesized are compounds which have not yet been reported. The key to the general hydrogenation/cyclization reaction is a highly active, selective and reusable nickel catalyst, which was identified from a library of 24 earth-abundant metal catalysts.

402-49-3, 4-Trifluoromethylbenzyl bromide is a useful research compound. Its molecular formula is C8H6BrF3 and its molecular weight is 239.03 g/mol. The purity is usually 95%.
4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond., Quality Control of 402-49-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Kolodziejski, Michal team published research in Inorganic Chemistry in 2021 | 20469-65-2

20469-65-2, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., Quality Control of 20469-65-2

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 20469-65-2, formula is C8H9BrO2, Name is 1-Bromo-3,5-dimethoxybenzene, Quality Control of 20469-65-2

Kolodziejski, Michal;Brock, Aidan J.;Kurpik, Gracjan;Walczak, Anna;Li, Feng;Clegg, Jack K.;Stefankiewicz, Artur R. research published 《 Charge Neutral [Cu2L2] and [Pd2L2] Metallocycles: Self-Assembly, Aggregation, and Catalysis》, the research content is summarized as follows. A range of morphol. distinct metallosupramol. Cu(II) and Pd(II) complexes was constructed, based on the tritopic ligand 1,1′,1”-(benzene-1,3,5-triyl)tris(4,4-dimethylpentane-1,3-dione) (H3L). By control of the reaction conditions, it is possible to generate distinct coordination assemblies possessing either macrocyclic or polymeric structures and more importantly distinct activity in catalysis of the Suzuki-Miyaura cross-coupling.

20469-65-2, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., Quality Control of 20469-65-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Kondo, Masaru team published research in ACS Catalysis in 2021 | 823-78-9

Application In Synthesis of 823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., 823-78-9.

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Application In Synthesis of 823-78-9.

Kondo, Masaru;Nakamura, Kento;Krishnan, Chandu G.;Takizawa, Shinobu;Abe, Tsukasa;Sasai, Hiroaki research published 《 Photoswitchable chiral phase transfer catalyst》, the research content is summarized as follows. Azo-crown ether-based photoswitching chiral phase transfer catalysts have been developed to control the catalytic activity by photoirradiation Azobenzene binaphthyl crown ether (ABCE) can switch its reactivity and selectivity through structural transformation of the crown ether moiety induced by E/Z photoisomerization of azobenzene. (Z)-ABCE promoted enantioselective alkylation of the glycine Schiff base to afford chiral amino acid derivatives in good yields with high enantiomer ratios. In contrast, (E)-ABCE hindered the reaction progress under the same conditions.

Application In Synthesis of 823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., 823-78-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Kang, Dongwei team published research in European Journal of Medicinal Chemistry in 2021 | 823-78-9

823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., Computed Properties of 823-78-9

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Computed Properties of 823-78-9.

Kang, Dongwei;Urhan, Cagil;Wei, Fenju;Frutos-Beltran, Estrella;Sun, Lin;Alvarez, Mar;Feng, Da;Tao, Yucen;Pannecouque, Christophe;De Clercq, Erik;Menendez-Arias, Luis;Liu, Xinyong;Zhan, Peng research published 《 Discovery, optimization, and target identification of coumarin derivatives as HIV-1 reverse transcriptase-associated ribonuclease H inhibitors》, the research content is summarized as follows. Despite significant advances in antiretroviral therapy, acquired immunodeficiency syndrome remains as one of the leading causes of death worldwide. New antiretroviral drugs combined with updated treatment strategies are needed to improve convenience, tolerability, safety, and antiviral efficacy of available therapies. In this work, a focused library of coumarin derivatives was exploited by cell phenotypic screening to discover novel inhibitors of HIV-1 replication. Compounds I, II, III, IV and V showed moderate activity against wild-type and drug-resistant strains of HIV-1 (IIIB and RES056). Four of those mols. were identified as inhibitors of the viral RT-associated RNase H. Structural modification of the most potent III and IV led to the discovery of compound 8a. This mol. showed increased potency against wild-type HIV-1 strain (EC50 = 3.94 ± 0.22 μM) and retained activity against a panel of mutant strains, showing EC50 values ranging from 5.62 μM to 202 μM. In enzymic assays, 8a was found to inhibit the viral RNase H with an IC50 of 12.3 μM. Mol. docking studies revealed that Me 5-(7,8-dihydroxy-6-nitro-2-oxo-2H-chromene-3carboxamido)-2-hydroxybenzoate could adopt a binding mode similar to that previously reported for other active site HIV-1 RNase H inhibitors.

823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., Computed Properties of 823-78-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Karki, Bhishma team published research in Materials Letters: X in 2022 | 585-76-2

585-76-2, 3-bromobenzoic acid is a bromobenzoic acid carrying a single bromo subsituent at the 3-position.
3-Bromobenzoic acid, also known as 3-Bromobenzoic acid, is a useful research compound. Its molecular formula is C7H5BrO2 and its molecular weight is 201.02 g/mol. The purity is usually 95%.
3-bromobenzoic acid is used as a reagent in the synthesis of deoxypodophyllotoxin derivatives with insecticidal activity. Also used as a reagent in the synthesis of thiazole derivatives with antibacterial activity.
3-bromobenzoic acid is a molecule that is classified as a Group P2. It has an electronegativity of 1.3 and an acidity of 0.8, which are both in the middle range of values for this group. 3-Bromobenzoic acid is soluble in water and is soluble in ethanol, acetone, and ether. The chemical structure of 3-bromobenzoic acid can be determined by its monoclonal antibody binding sites, electrochemical impedance spectroscopy data, and Langmuir adsorption isotherm data. 3-Bromobenzoic acid reacts with hydrochloric acid to form benzoate and HCl gas. Chronic exposure to 3-bromobenzoic acid has been shown to cause glutamate dehydrogenase inhibition, leading to an accumulation of p-hydroxybenzoic acid in the body. , SDS of cas: 585-76-2

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 585-76-2, formula is C7H5BrO2, The most pervasive is the naturally produced bromomethane. SDS of cas: 585-76-2

Karki, Bhishma;Dhobi, Saddam Husain;Yadav, Kishori;Gupta, Suresh Prasad;Nakarmi, Jeevan Jyoti;Pal, Amrindra research published 《 Comparative study of boron oxides crystal with different sources X-ray production sources (Cu, Ag, Mo, and Fe)》, the research content is summarized as follows. This work aims to study the XRD of 5 Boron oxides crystal with different X-ray sources using Quantum Expresso. When XRD was done with angle vs. intensity, a pretty exciting observation was observed: the single high-intensity peak was observed for each source. The high intensity with large Bragg′s angle is observed with Fe-sources among the considered source (Cu, Ag, Mo, and Fe). This shows lower at. mass sources have higher Bragg′s angle when incidence on a sample of Boron oxides. The high-intensity peak when Fe-sources is used for XRD of B6O, BO3, B2O, B8O, B2O3 was observed at an angle of 44.3, 37.5, 11, 44.3, 39.8 degrees, resp.

585-76-2, 3-bromobenzoic acid is a bromobenzoic acid carrying a single bromo subsituent at the 3-position.
3-Bromobenzoic acid, also known as 3-Bromobenzoic acid, is a useful research compound. Its molecular formula is C7H5BrO2 and its molecular weight is 201.02 g/mol. The purity is usually 95%.
3-bromobenzoic acid is used as a reagent in the synthesis of deoxypodophyllotoxin derivatives with insecticidal activity. Also used as a reagent in the synthesis of thiazole derivatives with antibacterial activity.
3-bromobenzoic acid is a molecule that is classified as a Group P2. It has an electronegativity of 1.3 and an acidity of 0.8, which are both in the middle range of values for this group. 3-Bromobenzoic acid is soluble in water and is soluble in ethanol, acetone, and ether. The chemical structure of 3-bromobenzoic acid can be determined by its monoclonal antibody binding sites, electrochemical impedance spectroscopy data, and Langmuir adsorption isotherm data. 3-Bromobenzoic acid reacts with hydrochloric acid to form benzoate and HCl gas. Chronic exposure to 3-bromobenzoic acid has been shown to cause glutamate dehydrogenase inhibition, leading to an accumulation of p-hydroxybenzoic acid in the body. , SDS of cas: 585-76-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Kaur, Ravneet team published research in Journal of Organic Chemistry in 2021 | 20469-65-2

HPLC of Formula: 20469-65-2, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., 20469-65-2.

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 20469-65-2, formula is C8H9BrO2, The most pervasive is the naturally produced bromomethane. HPLC of Formula: 20469-65-2

Kaur, Ravneet;Singh, Dipak;Singh, Ravi P. research published 《 Stereoselective Synthesis of Dihydrocoumarins via [1,2]-Phospha-Brook Rearrangement in Three-Component Coupling Reaction of α-Ketoesters, o-Quinone Methides, and Dialkyl Phosphites》, the research content is summarized as follows. A highly regio- and diastereoselective approach for the synthesis of phosphate substituted dihydrocoumarins I (R1 = 4-methoxyphenyl, 2-(4-methylphenyl)ethenyl, 2-phenylethenyl, etc.; R2 = Ph, 3-bromophenyl, 2-thienyl, etc.; R3 = i-Pr, Et, Ph) via Bronsted base catalyzed [1,2]-phospha-Brook rearrangement is reported. The two-step, one-pot Michael addition of α-phosphonyloxy enolates proceeds by coupling of dialkyl phosphite HP(=O)(OR3)2 and α-ketoesters R2C(O)C(O)OEt to o-quinone methides II, followed by an intramol. cyclization, providing 3,4-dihydrocoumarin frameworks I.

HPLC of Formula: 20469-65-2, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., 20469-65-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Ke, Jie team published research in Organic Letters in 2021 | 244205-40-1

Recommanded Product: (2-Bromophenyl)boronic acid, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Organic compounds having carbon bonded to bromine are called organic bromides. Recommanded Product: (2-Bromophenyl)boronic acid.

Ke, Jie;Zu, Bing;Guo, Yonghong;Li, Yingzi;He, Chuan research published 《 Hexafluoroisopropanol-Enabled Copper-Catalyzed Asymmetric Halogenation of Cyclic Diaryliodoniums for the Synthesis of Axially Chiral 2,2′-Dihalobiaryls》, the research content is summarized as follows. An efficient asym. halogenation of cyclic diaryliodonium salts was demonstrated, which gave access to a wide range of axially chiral 2,2′-dihalobiaryls in good to excellent yields and with excellent enantioselectivities. The use of CuX with chiral bisoxazoline ligand and tetrabutylammonium halides in the unique solvent of hexafluoroisopropanol (HFIP) led to the best results in the process. The axially chiral 2,2′-dihalobiaryls was transformed into a number of enantiopure chiral ligands that was potentially useful in asym. catalysis.

Recommanded Product: (2-Bromophenyl)boronic acid, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Kertsomboon, Thanit team published research in Polymer Degradation and Stability in 2020 | 2576-47-8

Product Details of C2H7Br2N, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., 2576-47-8.

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Product Details of C2H7Br2N.

Kertsomboon, Thanit;Chirachanchai, Suwabun research published 《 Amphiphilic biodegradable co-networks of Poly(butylene succinate)-Poly(ethylene glycol) chains for nano-gelation via Click chemistry and its potential dispersant for multi-walled carbon nanotubes》, the research content is summarized as follows. Amphiphilic nanogel (APNG) is a class of material miscible with water and oil which is practical for active mols. incorporation, water-oil dispersion, etc. In general, preparation of APNGs requires multi-steps involving the copolymer with different hydrophilic units and the micelles formation to confine the nano-level for the crosslink. The present work proposes a simple way to prepare APNGs by applying the co-networks of biodegradable hydrophilic and hydrophobic chains. The co-networks between alkyno-poly(acrylic acid) (alkyno-PAA) and diazido-poly(ethylene glycol) (N3-PEG-N3) as well as diazido-poly(butylene succinate) (N3-PBS-N3) via copper-catalyzed azide-alkyne cycloaddition (CuAAC) Click lead to APNG. The variation of hydrophilic N3-PEG-N3 and hydrophobic N3-PBS-N3 controls the amphiphilicity as evidenced from the swelling performances in various solvents with different polarity. The APNG obtained favors multi-walled carbon nanotubes (MWCNTs) to be dispersed in water for weeks without precipitation suggesting a potential dispersant of MWCNTs in hydrophilic media, especially aqueous solution

Product Details of C2H7Br2N, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., 2576-47-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Jin, Wangrui team published research in Journal of Medicinal Chemistry in 2022 | 585-76-2

Computed Properties of 585-76-2, 3-bromobenzoic acid is a bromobenzoic acid carrying a single bromo subsituent at the 3-position.
3-Bromobenzoic acid, also known as 3-Bromobenzoic acid, is a useful research compound. Its molecular formula is C7H5BrO2 and its molecular weight is 201.02 g/mol. The purity is usually 95%.
3-bromobenzoic acid is used as a reagent in the synthesis of deoxypodophyllotoxin derivatives with insecticidal activity. Also used as a reagent in the synthesis of thiazole derivatives with antibacterial activity.
3-bromobenzoic acid is a molecule that is classified as a Group P2. It has an electronegativity of 1.3 and an acidity of 0.8, which are both in the middle range of values for this group. 3-Bromobenzoic acid is soluble in water and is soluble in ethanol, acetone, and ether. The chemical structure of 3-bromobenzoic acid can be determined by its monoclonal antibody binding sites, electrochemical impedance spectroscopy data, and Langmuir adsorption isotherm data. 3-Bromobenzoic acid reacts with hydrochloric acid to form benzoate and HCl gas. Chronic exposure to 3-bromobenzoic acid has been shown to cause glutamate dehydrogenase inhibition, leading to an accumulation of p-hydroxybenzoic acid in the body. , 585-76-2.

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 585-76-2, formula is C7H5BrO2, Name is 3-Bromobenzoic acid. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Computed Properties of 585-76-2.

Jin, Wangrui;Zhang, Tao;Zhou, Wenbo;He, Peng;Sun, Yue;Hu, Shijia;Chen, Huang;Ma, Xinglong;Peng, Yangrui;Yi, Zhengfang;Liu, Mingyao;Chen, Yihua research published 《 Discovery of 2-Amino-3-cyanothiophene Derivatives as Potent STAT3 Inhibitors for the Treatment of Osteosarcoma Growth and Metastasis》, the research content is summarized as follows. A novel class of 2-amino-3-cyanothiophene derivatives I [R5 = Ph, 2-pyridyl, pyrimidin-4-yl, etc] and II [R6 = methoxy, methylpyrazolyl, anilino, etc] were designed and synthesized to inhibit osteosarcoma by targeting STAT3. Representative compound II [R6 = 4-methoxy anilino] showed potent antiproliferative effects against osteosarcoma cells, directly bound to the STAT3 SH2 domain with a KD of 0.46μM, and inhibited the phosphorylation of STAT3 Y705 in a dose-dependent manner. Furthermore, compound II [R6 = 4-methoxy anilino] promoted osteosarcoma cell apoptosis in vitro and significantly suppressed the growth and metastasis of osteosarcoma in vivo. These findings demonstrate that targeting STAT3 may be a feasible therapeutic strategy for the treatment of metastatic osteosarcoma.

Computed Properties of 585-76-2, 3-bromobenzoic acid is a bromobenzoic acid carrying a single bromo subsituent at the 3-position.
3-Bromobenzoic acid, also known as 3-Bromobenzoic acid, is a useful research compound. Its molecular formula is C7H5BrO2 and its molecular weight is 201.02 g/mol. The purity is usually 95%.
3-bromobenzoic acid is used as a reagent in the synthesis of deoxypodophyllotoxin derivatives with insecticidal activity. Also used as a reagent in the synthesis of thiazole derivatives with antibacterial activity.
3-bromobenzoic acid is a molecule that is classified as a Group P2. It has an electronegativity of 1.3 and an acidity of 0.8, which are both in the middle range of values for this group. 3-Bromobenzoic acid is soluble in water and is soluble in ethanol, acetone, and ether. The chemical structure of 3-bromobenzoic acid can be determined by its monoclonal antibody binding sites, electrochemical impedance spectroscopy data, and Langmuir adsorption isotherm data. 3-Bromobenzoic acid reacts with hydrochloric acid to form benzoate and HCl gas. Chronic exposure to 3-bromobenzoic acid has been shown to cause glutamate dehydrogenase inhibition, leading to an accumulation of p-hydroxybenzoic acid in the body. , 585-76-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Jin, Xin team published research in Mendeleev Communications in 2022 | 402-49-3

402-49-3, 4-Trifluoromethylbenzyl bromide is a useful research compound. Its molecular formula is C8H6BrF3 and its molecular weight is 239.03 g/mol. The purity is usually 95%.
4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond., COA of Formula: C8H6BrF3

Organic compounds having carbon bonded to bromine are called organic bromides. 402-49-3, formula is C8H6BrF3, Name is 1-(Bromomethyl)-4-(trifluoromethyl)benzene. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. COA of Formula: C8H6BrF3.

Jin, Xin;Yang, Tingting;Xia, Chenlu;Wang, Nina;Liu, Zi;Cao, Jianguo;Ma, Liang;Huang, Guozheng research published 《 Design and synthesis of alepterolic acid and 5-fluorouracil conjugates as potential anticancer agents》, the research content is summarized as follows. Conjugates of alepterolic acid with 5-fluorouracil derivatives I (Ar = Ph, 2,4-dichlorophenyl, 1-naphthyl, etc.) have been synthesized in 70-90% yields. The cytotoxic evaluation against two human cancer cell lines, viz. MCF-7 (breast) and A549 (lung), using MTT assay showed anticancer activities of the obtained compounds

402-49-3, 4-Trifluoromethylbenzyl bromide is a useful research compound. Its molecular formula is C8H6BrF3 and its molecular weight is 239.03 g/mol. The purity is usually 95%.
4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond., COA of Formula: C8H6BrF3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary