Tag: M.W=200-250

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 20469-65-2, formula is C8H9BrO2, The most pervasive is the naturally produced bromomethane. Quality Control of 20469-65-2

Guerra, Walter D.;Lucena-Agell, Daniel;Hortigueela, Rafael;Rossi, Roberto A.;Fernando Diaz, J.;Padron, Jose M.;Barolo, Silvia M. research published ã€?Design, Synthesis, and in vitro Evaluation of Tubulin-Targeting Dibenzothiazines with Antiproliferative Activity as a Novel Heterocycle Building Blockã€? the research content is summarized as follows. A series of free NH and N-substituted dibenzonthiazines I [R¹ = H, F, CF₃, Ph; R² = H, 9-F, 7-Ph, etc.; R³ = H, Me, Bn, etc.] with potential anti-tumor activity from N-aryl-benzenesulfonamides was prepared A biol. test of synthesized compounds was performed in vitro measuring their antiproliferative activity against a panel of six human solid tumor cell lines and its tubulin inhibitory activity. Compounds I [R¹ = R² = H; R³ = SO₂C₆H₅, 4-MeC₆H₄SO₂] showed as the best compounds with promising values of activity (overall range of 2-5.4μM).

20469-65-2, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., Quality Control of 20469-65-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 585-76-2, formula is C7H5BrO2, Name is 3-Bromobenzoic acid, Reference of 585-76-2

Guo, Chunfang;Han, Xuliang;Feng, Yu;Liu, Zhaolong;Li, Yueyun;Liu, Hui;Zhang, Lizhi;Dong, Yunhui;Li, Xinjin research published ã€?Straightforward Synthesis of Alkyl Fluorides via Visible-Light-Induced Hydromono- and Difluoroalkylations of Alkenes with α-Fluoro Carboxylic Acidsã€? the research content is summarized as follows. Reported the first visible-light-induced hydromono- and difluoroalkylations of alkenes with inexpensive and easily accessible α-fluoro carboxylic acids. This metal-free protocol exhibits mild conditions, high efficiency and excellent functional-group tolerance, provided a straightforward approach to mono- and difluoroalkylated alkanes. Moreover, the fluorine effect on the hydrofluoroalkylation reaction was discussed in detail.

585-76-2, 3-bromobenzoic acid is a bromobenzoic acid carrying a single bromo subsituent at the 3-position.
3-Bromobenzoic acid, also known as 3-Bromobenzoic acid, is a useful research compound. Its molecular formula is C7H5BrO2 and its molecular weight is 201.02 g/mol. The purity is usually 95%.
3-bromobenzoic acid is used as a reagent in the synthesis of deoxypodophyllotoxin derivatives with insecticidal activity. Also used as a reagent in the synthesis of thiazole derivatives with antibacterial activity.
3-bromobenzoic acid is a molecule that is classified as a Group P2. It has an electronegativity of 1.3 and an acidity of 0.8, which are both in the middle range of values for this group. 3-Bromobenzoic acid is soluble in water and is soluble in ethanol, acetone, and ether. The chemical structure of 3-bromobenzoic acid can be determined by its monoclonal antibody binding sites, electrochemical impedance spectroscopy data, and Langmuir adsorption isotherm data. 3-Bromobenzoic acid reacts with hydrochloric acid to form benzoate and HCl gas. Chronic exposure to 3-bromobenzoic acid has been shown to cause glutamate dehydrogenase inhibition, leading to an accumulation of p-hydroxybenzoic acid in the body. , Reference of 585-76-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 402-49-3, formula is C8H6BrF3, Name is 1-(Bromomethyl)-4-(trifluoromethyl)benzene. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. COA of Formula: C8H6BrF3.

Guo, Jianan;Zhang, Yujia;Zhang, Changjun;Yao, Chuansheng;Zhang, Jingqi;Jiang, Xiaoying;Zhong, Zhichao;Ge, Jiamin;Zhou, Tao;Bai, Renren;Xie, Yuanyuan research published ã€?N-Propargylamine-hydroxypyridinone hybrids as multitarget agents for the treatment of Alzheimer diseaseã€? the research content is summarized as follows. AD is a progressive brain disorder. Because of the lack of remarkable single-target drugs against neurodegenerative disorders, the multitarget-directed ligand strategy has received attention as a promising therapeutic approach. Herein, we rationally designed twenty-nine hybrids of N-propargylamine-hydroxypyridinone. The designed hybrids possessed excellent iron-chelating activity (pFe3+ = 17.09-22.02) and potent monoamine oxidase B inhibitory effects. Various biol. evaluations of the optimal compound 6b were performed step by step, including inhibition screening of monoamine oxidase (hMAO-B IC50 = 0.083 ± 0.001 μM, hMAO-A IC50 = 6.11 ± 0.08 μM; SI = 73.5), prediction of blood-brain barrier permeability and mouse behavioral research. All of these favorable results proved that the N-propargylamine-hydroxypyridinone scaffold is a promising structure for the discovery of multitargeted ligands for AD therapy.

402-49-3, 4-Trifluoromethylbenzyl bromide is a useful research compound. Its molecular formula is C8H6BrF3 and its molecular weight is 239.03 g/mol. The purity is usually 95%.
4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond., COA of Formula: C8H6BrF3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 402-49-3, formula is C8H6BrF3, Name is 1-(Bromomethyl)-4-(trifluoromethyl)benzene. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Related Products of 402-49-3.

Guo, Rui;Sang, Jiale;Xiao, Haijing;Li, Junxia;Zhang, Guozhu research published ã€?Development of Novel Phosphino-Oxazoline Ligands and Their Application in Asymmetric Alkynlylation of Benzylic Halidesã€? the research content is summarized as follows. A new set of stereochem. diverse phosphino-oxazoline ligands derived from simple L-amino acids and 2-(diphenylphosphanyl)benzoic acid were developed. Those mono anionic tridentated N,N,P-ligands promote the Cu-catalyzed enantioselective radical coupling of terminal alkynes with a broad range of benzylic halides including benzo-fused cyclic α-halides and α-silyl benzyl halides in high yield and excellent enantioselectivity under mild reaction conditions. With multi distinct sites for structural modification, a diverse pool of chiral N,N,P-ligands is readily accessed, allowing for rapid optimization of the ligand structure for a specific substrate. Notably, the enantioselective alkynlylation of benzylic halides bonds in benzo-cyclic mols. has also been realized for the first time.

Related Products of 402-49-3, 4-Trifluoromethylbenzyl bromide is a useful research compound. Its molecular formula is C8H6BrF3 and its molecular weight is 239.03 g/mol. The purity is usually 95%.
4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond., 402-49-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 402-49-3, formula is C8H6BrF3, Name is 1-(Bromomethyl)-4-(trifluoromethyl)benzene. Organobromine compounds have fallen under increased scrutiny for their environmental impact., COA of Formula: C8H6BrF3.

Guo, Yating;Jiang, Xiaoding;Chang, Qi;Xiao, Zhihong;Chen, Zhuo;Jiang, Dejian;Hu, Gaoyun;Li, Qianbin research published ã€?Novel pyrazolo[3,4-b]pyridine derivatives: Synthesis, structure-activity relationship studies, and regulation of the AMPK/70S6K pathwayã€? the research content is summarized as follows. A series of novel pyrazolo[3,4-b]pyridine derivatives were designed, synthesized, and biol. evaluated for anti-lung cancer activity. Structure-activity relationship and AutoGPA models were constructed based on the in vitro antiproliferative potency of the compounds against a human lung adenocarcinoma cell line (A549). Compound 9d exhibits improved potency for A549 cell growth inhibition (3.06 ± 0.05 μM) compared with A-769662 (45.29 ± 2.14 μM). Compound 9d can elevate the phosphorylation levels of adenosine monophosphate-activated protein kinase (AMPK) and its substrate acetyl-CoA carboxylase and reduce the level of phosphorylated ribosomal S6 kinase (p-70S6K) at 1 μM, which is comparable to the activity of A-769662 at 20 μM. 9d induced G2/M cell cycle arrest, which was rescued when co-incubated with “Compound C,” a potent AMPK inhibitor. Taken together, compound 9d showed potential anti-lung cancer activity via inducing cell cycle arrest by regulation of the AMPK/70S6K pathway in A549 cells, which could provide a new lead for the discovery of anti-lung cancer agents.

COA of Formula: C8H6BrF3, 4-Trifluoromethylbenzyl bromide is a useful research compound. Its molecular formula is C8H6BrF3 and its molecular weight is 239.03 g/mol. The purity is usually 95%.
4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond., 402-49-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Product Details of C7H6Br2.

Ghosh, Prithwish;Byun, Youjung;Kwon, Na Yeon;Kang, Ju Young;Mishra, Neeraj Kumar;Park, Jung Su;Kim, In Su research published ã€?Reactivity of triplet diradical intermediates in aqueous media for transition-metal-free Csp²-H alkylationã€? the research content is summarized as follows. Herein, a distinct reaction pathway involving triplet diradical intermediates in the coupling reaction between alkyl pyridinium ylides and electrophilic N-heterocyclic mols. was reported. Alkyl pyridinium ylides generated from alkyl pyridinium salts under basic aqueous conditions underwent addition into iminoamido N-heterocycles, generating triplet diradical intermediates lead to C-H alkylated N-heterocycles I [R = Me, Bn, 2-pyridyl, etc.; R¹ = Br, Ph, 2-thienyl, etc.; R² = Bn, CH₂-2-FC₆H₄, CH₂-2-naphthyl, etc.], II [R³ = Me, allyl, iPr, etc.; R⁴ = H, Cl; R⁵ = Bn, CH₂-4-MeOC₆H₄, CH₂-2-furyl, etc.; X = CH, N] and III [R⁶ = Me, 3-MeC₆H₄; R⁷ = Ph, Bn, 4-EtOC₆H₄, etc.]. The proposed reaction mechanism was supported by ESR and radical scavenging experiments Notably, a wide substrate scope and excellent level of functional group tolerance were attained under cost-effective and straightforward conditions, which revealed the amenability of this protocol in the pharmaceutical and chem. industries. These results were of significant relevance to the organic and medicinal chemists because of the handling simplicity, broad substrate scope, high efficiency, excellent chemoselectivity and the environmentally friendly conditions of the developed methodol.

Product Details of C7H6Br2, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., 823-78-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 823-78-9, formula is C7H6Br2, The most pervasive is the naturally produced bromomethane. SDS of cas: 823-78-9

Ghotbi, Golaleh;Mahdavi, Mohammad;Najafi, Zahra;Moghadam, Farshad Homayouni;Hamzeh-Mivehroud, Maryam;Davaran, Soodabeh;Dastmalchi, Siavoush research published ã€?Design, synthesis, biological evaluation, and docking study of novel dual-acting thiazole-pyridiniums inhibiting acetylcholinesterase and β-amyloid aggregation for Alzheimer’s diseaseã€? the research content is summarized as follows. New compounds containing thiazole and pyridinium moieties were designed and synthesized. The potency of the synthesized compounds as selective inhibitors of acetylcholinesterase (AChE), and β-amyloid aggregation (Aβ) was evaluated. Compounds 7d and 7j showed the best AChE inhibitory activities at the submicromolar concentration range (IC₅₀ values of 0.40 and 0.69μM, resp.). Most of the novel compounds showed moderate to low inhibition of butyrylcholinesterase (BChE), which is indicative of their selective inhibitory effects towards AChE. Kinetic studies using the most potent compounds 7d and 7j confirmed a mixed-type of AChE inhibition mechanism in accordance with the docking results, which shows their interactions with both catalytic active (CAS) and peripheral anionic (PAS) sites. The specific binding of 7a, 7j, and 7m to PAS domain of AChE was also confirmed exptl. In addition, 7d and 7j were able to show β-amyloid self-aggregation inhibitory effects (20.38 and 42.66% resp.) stronger than donepezil (14.70%) assayed at 10μM concentration Moreover, compounds 7j and 7m were shown to be effective neuroprotective agents in H₂O₂-induced oxidative stress on PC₁₂ cells almost similar to those observed for donepezil. The ability of 7j to pass blood-brain barrier was demonstrated using the PAMPA method. The results presented in this work provide useful information about designing novel anti-Alzheimer agents.

SDS of cas: 823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., 823-78-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Related Products of 5392-10-9.

Glas, Carina;Wirawan, Ricky;Bracher, Franz research published �A Short Approach to N -Aryl-1,2,3,4-tetrahydroisoquinolines from N -(2-Bromobenzyl)anilines via a Reductive Amination/Palladium-Catalyzed Ethoxyvinylation/Reductive N-Alkylation Sequence� the research content is summarized as follows. N-Aryl-1,2,3,4-tetrahydroisoquinolines are obtained via a convenient and short protocol with a broad range of substituents on both aromatic rings and high functional group tolerance. Starting from readily available ortho-brominated aromatic aldehydes and primary aromatic amines, condensation of these building blocks under reductive conditions gives N-aryl 2-bromobenzylamines. The C-3/C-4-unit of the tetrahydroisoquinoline is introduced using com. available 2-ethoxyvinyl pinacolboronate under Suzuki conditions. Finally, the obtained crude ortho-ethoxyvinyl benzylamines are cyclized via an intramol. reductive amination using the combination of triethylsilane/TFA to give the desired N-aryl-1,2,3,4-tetrahydroisoquinolines.

Related Products of 5392-10-9, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., 5392-10-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 2576-47-8, formula is C2H7Br2N, Name is 2-Bromoethylamine hydrobromide. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Recommanded Product: 2-Bromoethylamine hydrobromide.

Gradiski, Matthew V.;Kharat, Ali Nemati;Ong, Maegan S. E.;Lough, Alan J.;Smith, Samantha A. M.;Morris, Robert H. research published ã€?A One-Step Preparation of Tetradentate Ligands with Nitrogen and Phosphorus Donors by Reductive Amination and Representative Iron Complexesã€? the research content is summarized as follows. The synthesis and use of the first examples of unsym., mixed phosphine donor tripodal NPP₂‘ ligands N(CH₂CH₂PR₂)₂(CH₂CH₂PPh₂) are presented. The ligands are synthesized via a convenient, one pot reductive amination using 2-(diphenylphosphino)ethylamine and various substituted phosphonium dimers in order to introduce mixed phosphine donors substituted with P/P’, those being Ph/Cy (2), Ph/ⁱPr (3), Ph/ⁱBu (4), Ph/o-Tol (5), and Ph/p-Tol (6). Addnl., authors have developed the first known synthesis of a sym. tripodal NP₃ ligand N(CH₂CH₂PⁱBu₂)₃ using bench safe ammonium acetate as the lone nitrogen source (7). This new protocol eliminates the use of extremely dangerous nitrogen mustard reagents typically required to synthesize NP₃ ligands. Some of these tetradentate ligands and also P₂NN’ ligands N(CH₂-o-C₅H₄N)(CH₂CH₂PR₂)₂ (P₂NN’-Cy, R = Cy; P₂NN’-Ph, R = Ph) prepared by reductive amination using 2-picolylamine are used in the synthesis and reactions of iron complexes. FeCl₂(P₂NN’-Cy) (8) undergoes single halide abstraction with NaBPh₄ to give the trigonal bipyramidal complex [FeCl(P₂NN’-Cy)][BPh₄] (9). Upon exposure to CO(g), complex 9 readily coordinates CO giving [FeCl(P₂NN’-Cy)(CO)][BPh₄] (10), and further treatment with an excess of NaBH₄ results in formation of the hydride complex [Fe(H)(P₂NN’-Cy)(CO)][BPh₄] (11). Their previously reported complex FeCl₂(P₂NN’-Ph) undergoes double halide abstraction with NaBPh₄ in the presence of the coordinating solvent to give [Fe(NCMe)₂(P₂NN’-Ph)][BPh₄]₂ (12). Ligand 3 can be coordinated to FeCl₂, and upon sequential halide abstraction, treatment with NaBH₄, and exposure to an atm. of dinitrogen, the dinitrogen hydride complex [Fe(H)(NPP₂‘-ⁱPr)(N₂)][BPh₄] (13) is isolated. Sym. NP₃ ligand 7 can also be coordinated to FeCl₂ and, upon exposure to an atm. of CO(g), selectively forms [FeCl(NP₃)(CO)][BPh₄] (14) after salt metathesis with NaBPh₄. Complex 14 can be treated with an excess of NaBH₄ to give the hydride complex [Fe(H)(NP₃)(CO)][BPh₄] (15), which can further be deprotonated/reduced to the Fe(0) complex Fe(NP₃)(CO) (16) upon treatment with an excess of KH. The synthesis of novel unsym. tripodal mixed phosphine donor NPP₂‘ ligands is reported. These are used to synthesize a range of iron complexes. A sym. tripodal NP₃ ligand is made from ammonium acetate and is used to synthesize the first Fe(0) NP₃ complex among others.

Recommanded Product: 2-Bromoethylamine hydrobromide, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,â€?0,â€?5,â€?0-​tetrakis(1-​methylpyridinium-â€?-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,â€?0,â€?5,â€?0-​tetrakis(1-​methylpyridinium-â€?-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., 2576-47-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. COA of Formula: C6H6BBrO2.

Gragert, Maria M.;Tomov, Atanas K.;Bettonville, Serge;Pannier, Gaelle;White, Andrew J. P.;Britovsek, George J. P. research published �Biaryl Group 4 Metal Complexes as Non-Metallocene Catalysts for Polyethylene with Long Chain Branching� the research content is summarized as follows. A series of biaryl Group 4 complexes with a bidentate and a tridentate pincer ligand have been synthesized and characterized. The complexes have been applied as metallocene analogs for the controlled polymerization of ethylene and the copolymerization of ethylene and 1-hexene, with a particular focus on the control of the degree of long chain branching in these polymers.

COA of Formula: C6H6BBrO2, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary