Tag: M.W=200-250

Zang, Yu published the artcileSynthesis and Oxygen Permeation of Well-Defined Multistranded Copolymers from Monomers Having Two Different Polymerizable Groups, Synthetic Route of 143-15-7, the publication is Macromolecules (Washington, DC, United States) (2022), 55(13), 5699-5710, database is CAplus.

Four multistranded copolymers were synthesized by two-step selective polymerization of monomers having an acetylene and two olefins. Their second main chains, which were formed at the postpolymn. between the olefin groups in the template acetylene polymers, are categorized into two types, i.e., helical conformations along with the conformations of their template helical polymers and nonhelical conformations parallel to the direction of the main chain of their precursor polymers. The numbers of the strands are two, four, and seven when supramol. strands by hydrogen bonds are included. Since the copolymers were all soluble, they could be fully characterized and fabricated to self-standing membranes. The conversions of the postpolymns. were high. The degree of the postpolymn. could be controlled by changing conditions. Oxygen permselectivies of these multistranded copolymers were better than the corresponding template polymers. The more the number of the strands was, the higher their oxygen permselectivity showed.

Macromolecules (Washington, DC, United States) published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C7H16Cl2Si, Synthetic Route of 143-15-7.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Negishi, Eiichi published the artcileSelective carbon-carbon bond formation via transition metal catalysis. 35. A convenient synthesis of unsymmetrical bibenzyls, homoallylarenes, and homopropargylarenes via palladium-catalyzed cross coupling, Name: (4-Bromobut-1-yn-1-yl)trimethylsilane, the publication is Tetrahedron Letters (1983), 24(36), 3823-4, database is CAplus.

The Pd-catalyzed homobenzyl-aryl, homobenzyl-alkenyl, homoallyl-aryl, and homopropargyl-aryl cross coupling reactions provide the desired coupling products, 2-MeC₆H₄CH₂CH₂Ph, (E)-PhCH₂CH₂CH:CMe(CH₂)₅Me, 4-NCC₆H₄CH₂CH₂CH:CH₂, Me₃SiCCCH₂CH₂Ph, in high yields. Similar reactions involving alkynyl halides lead to low product yields.

Tetrahedron Letters published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Name: (4-Bromobut-1-yn-1-yl)trimethylsilane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Hintz, Sandra published the artcileRegio- and stereoselective cyclization reactions of unsaturated silyl enol ethers by photoinduced electron transfer. Mechanistic aspects and synthetic approach, Product Details of C7H13BrSi, the publication is European Journal of Organic Chemistry (1998), 1583-1596, database is CAplus.

Oxidative photoinduced electron transfer (PET) reactions were performed with various silyl enol ethers and silyloxy-2H-chromones bearing an olefinic or silylacetylenic side-chain. The reactions result in regioselective ring-closure with the formation of bi- to tetracyclic ring systems with a well-defined ring juncture, e.g. perhydrophenanthrenones or benzo-annelated xanthenones. Our investigations have focussed on the optimization of this cyclization method with regard to irradiation time and product yield. The irradiation times could be reduced by using the cosensitized PET method. Modifying the substrate at the silyl group led to enhanced yields. In addition, it was found that solvent and pressure dependences are important tools, allowing control of the regiochem. Both the synthesis of 6-endo products by radical cationic reaction pathways as well as 5-exo ring-closure by radical intermediates was achieved. Mechanistic details, including findings from deuterium labeling experiments, are discussed.

European Journal of Organic Chemistry published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Product Details of C7H13BrSi.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Rinderhagen, Heiko published the artcileSynthetic applications in radical/radical cationic cascade reactions, COA of Formula: C7H13BrSi, the publication is Chemistry – A European Journal (2004), 10(4), 851-874, database is CAplus and MEDLINE.

Oxidative photoinduced electron transfer (PET) reactions have been performed with various cyclic cyclopropyl(vinyl) silyl ethers bearing an olefinic or acetylenic side chain. The reactions result in bi- to tetracyclic ring systems via a fragmentation-radical/radical cationic addition reaction pathway with well defined ring juncture. The mode of cyclization (endo/exo) can be partially controlled by addition of nucleophiles due to the suppression of radical cationic reaction pathways. Quantum chem. calculation of the cyclization transition states underline the exptl. found selectivities. Addnl. mechanistic studies concerning the saturation step reveal that the final radical is saturated mostly by the solvent and traces of water in the solvent.

Chemistry – A European Journal published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, COA of Formula: C7H13BrSi.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Mathey, Francois published the artcilePyrolysis of some phosphorus trihalide-diene addition compounds, Recommanded Product: 2,3-Dibromo-2,3-dimethylbutane, the publication is Comptes Rendus des Seances de l’Academie des Sciences, Serie C: Sciences Chimiques (1969), 268(21), 1902-4, database is CAplus.

Pyrolysis of H2C:-CMeCMe:CH2.PBr3, H2C:CMeCMe:CH2.PCl3, and H2C:-CMeCH:CH2.PBr3 in vacuo at <200° gave, resp., PBr3 or PCl3 and Me2CBrCBrMe2, ClCH2CHMeCClMe2 or BrCH2CH2CBrMe2 together with polymeric residues. The products were identified by their N.M.R. spectra, which are discussed.

Comptes Rendus des Seances de l’Academie des Sciences, Serie C: Sciences Chimiques published new progress about 594-81-0. 594-81-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 2,3-Dibromo-2,3-dimethylbutane, and the molecular formula is C6H12Br2, Recommanded Product: 2,3-Dibromo-2,3-dimethylbutane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Uslu, Azize Gizem published the artcileBenzimidazole derivatives as potent and isoform selective tumor-associated carbonic anhydrase IX/XII inhibitors, Recommanded Product: 4-Bromo-N-methyl-2-nitroaniline, the publication is Bioorganic Chemistry (2020), 103544, database is CAplus and MEDLINE.

We describe the synthesis of a series of 2-arylbenzimidazole derivatives bearing sulfonamide functionality (4a-d, 7a-c and 10) as well as hydroxamic acid (15a-b), carboxylic acid (16a-b), carboxamide (17a-b) and boronic acid (22a-b and 26) functionalities, which act as human carbonic anhydrase (hCA, EC 4.2.1.1) inhibitors. The newly synthesized benzimidazole derivatives were evaluated against 4 physiol. relevant CA isoforms (hCA I, II, IX, and XII), and especially the sulfonamide-containing benzimidazoles demonstrated intriguing inhibitory activity against tumor associated CA IX and XII with K_I values in the range of 5.2-29.3 nM and 9.9-41.7 nM, resp. Notably, compound 4c was the most potent and selective CA IX (K_I = 6.6 nM) and XII (K_I = 9.9 nM) inhibitor with a significant selectivity ratio over cytosolic CA I and II isoforms in the range of 3.4-25.2. In addition, compounds having hydroxamic acid (15a-b) or carboxylic acid (16a-b) functionalities resulted in greater selectivity ratios for CA IX/XII over CAI/II in the range of 4.1-121.5 although with K_I values in lower micromolar potency (K_Is = 0.36-0.85μM for CA IX/XII).

Bioorganic Chemistry published new progress about 53484-26-7. 53484-26-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Nitro Compound,Amine,Benzene, name is 4-Bromo-N-methyl-2-nitroaniline, and the molecular formula is C7H6Cl2, Recommanded Product: 4-Bromo-N-methyl-2-nitroaniline.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Gu, Jilong published the artcileAnhydrous proton conduction in protic ionic liquid crystals formed by 1-alkyl-3H-imidazolium hydrogen sulfates, Related Products of bromides-buliding-blocks, the publication is Ionics (2022), 28(5), 2293-2300, database is CAplus.

Dynamic self-assembly of liquid crystals favors the formation of hydrogen bond networks essential for anhydrous proton conduction. To endow liquid crystals with inherently exchangeable protons for proton conduction, protic 1-alkyl-3H-imidazolium hydrogen sulfates ([C_nIm][HSO₄]) with different lengths of alkyl chains are synthesized. Interdigitated smectic A_d (S_Ad) liquid crystal phases are observed for [C_nIm][HSO₄], in which the protic ionic pairs aggregate into lamellas. Electrochem. characterization reveals that the anhydrous proton conductivity of [C_nIm][HSO₄] reaches up to 5.3 mS cm^-1 in the S_Ad phase. The single fuel cells fabricated from the [C_nIm][HSO₄]@PVDF supported membranes exhibit a peak power d. of 2.6 mW cm^-2 at 130 °C under non-humidified conditions. It was the enriched lamellar hydrogen bond networks formed by the protic ionic pairs that contribute to the anhydrous proton conduction. The protic ionic liquid crystals possess a great potential to construct electrochem. devices involving anhydrous proton conduction.

Ionics published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H25Br, Related Products of bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Song, Jinming published the artcileReversible Multilevel Stimuli-Responsiveness and Multicolor Room-Temperature Phosphorescence Emission Based on a Single-Component System, Recommanded Product: 1-Bromododecane, the publication is Angewandte Chemie, International Edition (2022), 61(29), e202206157, database is CAplus and MEDLINE.

There are limited reports about the transformation of pure organic room-temperature phosphorescence (RTP) materials with multilevel stimuli-responsiveness at different RTP emission wavelengths under external stimuli. It is difficult to ensure efficient intersystem crossing (ISC) in different states of a single-component system. This research reports the conversion of the organic single-component small mol. 1,2-bis(4-alkoxyphenyl)ethane-1,2-dione (N-BOX) with multilevel stimuli-responsiveness between high-efficiency blue and yellow RTP by grinding or thermal annealing N-BOX crystals. The RTP emission of N-BOX in the crystalline state was easy to adjust by external stimuli (grinding or thermal annealing) due to its non-compact packing, which led to a phase transition and generated unique multilevel stimuli-responsiveness. In particular, the RTP quantum yield of 7-BOX with multilevel stimuli-responsiveness reached 68.4%, which provides an opportunity for regulation of smart optical materials based on pure organic RTP.

Angewandte Chemie, International Edition published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C16H20N2, Recommanded Product: 1-Bromododecane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Mukku, Narasimharao published the artcileA Facile Microwave-Assisted Synthesis of Oxazoles and Diastereoselective Oxazolines Using Aryl-Aldehydes, p-Toluenesulfonylmethyl Isocyanide under Controlled Basic Conditions, Formula: C9H6BrNO, the publication is ACS Omega (2020), 5(43), 28239-28248, database is CAplus and MEDLINE.

In this study, a highly efficient two-component [3+2] cycloaddition reaction of substituted aryl aldehydes with 4-toluenesulfonylmethyl isocyanide (TosMIC) in the presence of 2 equiv of potassium phosphate as a base to 5-substituted oxazoles were established in a isopropanol medium under microwave irradiation However, using 1 equiv of K₃PO₄ as a base resulted in the diastereoselective synthesis of 4,5-disubstituted oxazolines under identical reaction conditions. The foremost benefits of these protocols are the moderate-to-excellent yields with good functional group compatibility, simple exptl. procedure, inexpensive readily available starting materials, nonchromatog. purification, and high bond-forming efficiency. The synthetic manipulation reported herein represents a cleaner route to the sustainable preparation of 5-substituted oxazoles and diastereoselective 4,5-disubstituted oxazolines derivatives

ACS Omega published new progress about 243455-57-4. 243455-57-4 belongs to bromides-buliding-blocks, auxiliary class Oxazole,Bromide,Benzene, name is 5-(3-Bromophenyl)oxazole, and the molecular formula is C9H6BrNO, Formula: C9H6BrNO.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Krylov, Ivan M. published the artcileAccess to Functionalized α-Trifluoromethyl-α-aminophosphonates via Intermolecular Ene-Yne Metathesis, Application of (4-Bromobut-1-yn-1-yl)trimethylsilane, the publication is Synlett (2014), 25(18), 2624-2628, database is CAplus.

An efficient approach to a new family of highly functionalized P analogs of α-trifluoromethyl-substituted phenylalanine and its homologues using ruthenium-catalyzed intermol. ene-yne metathesis as a key step of the reaction sequence has been developed. The method includes cross metathesis of α-alkynyl-α-trifluoromethyl-α-aminophosphonates with alkenes under catalysis by second-generation Grubbs carbene complex to afford the corresponding aminophosphonates with 1,3-diene backbone followed by one-pot Diels-Alder reaction-aromatization step.

Synlett published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Application of (4-Bromobut-1-yn-1-yl)trimethylsilane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary