Tag: M.W=200-250

Fu, Wen published the artcileSynthesis of polymerizable quaternary thiazole salts and their application as antibacterial agents for dental resin, Name: 1-Bromododecane, the publication is Journal of the Mechanical Behavior of Biomedical Materials (2022), 105183, database is CAplus and MEDLINE.

For the purpose of endowing dental resin with antibacterial activity without impairing physicochem. properties, polymerizable quaternarized thiazole salts (QAMEMT-x) with different alkyl chain length (12, 14, and 16) were synthesized and characterized by FT-IR and ¹H-NMR spectra. After adding 5 wt% of QAMEMT-x into Bis-GMA/TEGDMA (50/50, weight/weight) dental resin, double bond conversion (DC), volumetric shrinkage (VS), flexural strength (FS) and modulus (FM), water sorption (WS) and solubility (SL), and antibacterial activity against Streptococcus mutans (S. mutans) of obtained resin systems were investigated. The results showed that 5 wt% of QAMEMT-x had no influence on DC, FS, FM, WS, and SL (α > 0.05), while could reduce VS of dental resin (α < 0.05). Cured resins with 5 wt% of QAMEMT-x all showed antibacterial activity against S. mutans, and QAMEMT-16 could endow cured resin with the strongest antibacterial activity which showed an antibacterial efficiency of more than 99%.

Journal of the Mechanical Behavior of Biomedical Materials published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H25Br, Name: 1-Bromododecane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Kharasch, M. S. published the artcileVapor-phase photochemical bromination of 2,3-dimethylbutane and 2,2,4,4-tetramethylpentane, Category: bromides-buliding-blocks, the publication is Journal of Organic Chemistry (1955), 680-8, database is CAplus.

cf. C.A. 50, 173e. The vapor-phase, photochem. bromination of 700 g. (CHMe₂)₂ (I) with 360 g. Br is carried out in the apparatus described earlier (cf. Zimmt, Dissertation, Univ. of Chicago, 1951). After 10 h. the bromination products are stripped of HBr with N and the residue is fractionally distilled, giving 35% 2-bromo-2,3-dimethylbutane, b_27.5 41-1.5°, n_D²⁰ 1.4541. Cooling the distillation residue gives 4% (CBrMe₂)₂, subliming 170-5° without melting. High-vacuum distillation of the high-boiling residue gives 3 fractions: (a) 46 g., b_0.2 44-6°; (b) 5.4 g., b_0.2 67-70°; (c) 10.1 g., b_0.4 96-100°. Redistillation of a gives 25% of a mixture of cis- and trans-(:CMeCH₂Br)₂, b_0.1 40°, needles, m. 57-7.5°; b is a mixture of tri- and tetrabromides and is not investigated further; recrystallization of c gives 5% tetrabromide, needles, m. 149-52°, of unknown structure. Treating 2 g. of a in 25 cc. CCl₄ with 1.5 g. Br 40 min. at 20° with moderate illumination gives 1.8 g. (CBrMeCH₂Br)₂, faintly yellow needles, m. 137-8°. Because little or no bromination of 2,2,4,4-tetramethylpentane (II) occurs in the vapor phase photochem. bromination at 100° and because of the limited amount of II available a special apparatus, similar to that for I, is used. The bromination of 27 g. II with 14 g. Br is carried out over a period of 7.5 h. at 200°. The reaction product is freed of Br and HBr with N and fractionally distilled in vacuo giving 3 fractions: (d) 0.7 g., b₅ 51°, n_D²⁰ 1.4690; (e) 1.1 g., b₅ 51-2°, n_D²⁰ 1.4695; (f) 11.2 g., b₅ 52°, n_D²⁰ 1.4719; and 0.6 g. residue, apparently a dibromide. The total yield of d-f is 72.2% and is shown to be 2-bromo-2,3,4,4-tetramethylpentane (III). Treating f 0.5 h. with AgNO₃ gives 92.5% AgBr. Shaking 2.1 g. f with 2 g. AgOAc in 30 cc. AcOH and 0.3 cc. Ac₂O 1 h. and distilling off the solvent in vacuo leave 0.5 g. residue which gives a pos. hydroxamic acid test for esters. Neutralizing the distillate with Na₂CO₃, extracting with Et₂O, and evaporating the extract leave 0.6 g. unsaturated material which, on ozonization, gives HCHO. Shaking 2.07 g. f in 45 cc. anhydrous Et₂O with 7.3 g. 3,4-(O₂N)₂C₆H₃CO₂Ag 36 h. gives 2,3,4,4-tetramethylpent-1-ene, b₇₅₄ 125-6°, n_D²⁰ 1.4261, which (0.1 g.), ozonized in 100 cc. EtOAc 2.5 min. at -40°, gives 3,4,4-trimethylpentan-2-one identified via its 2,4-dinitrophenylhydrazone, orange needles, m. 109-10°. III is formed by rearrangement of a Me group. Mechanisms which account for the formation of mono- and dibromides with free radicals as intermediates are proposed.

Journal of Organic Chemistry published new progress about 594-81-0. 594-81-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 2,3-Dibromo-2,3-dimethylbutane, and the molecular formula is C6H12Br2, Category: bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Bladon, P. published the artcileLattice defects in plastic organic solids. 9. Nuclear magnetic resonance studies of translational molecular motion in solids of intermediate entropies of fusion, Application of 2,3-Dibromo-2,3-dimethylbutane, the publication is Molecular Crystals and Liquid Crystals (1973), 19(3-4), 315-26, database is CAplus.

Studies were made of the effects of temperature and sample purity on the continuous wave, NMR line narrowing behavior at high temperatures for the following rotator phase organic solids of intermediate entropies of fusion: perfluorocyclohexane, triethylenediamine, 2-bromo-2,3,3-trimethylbutane, 2-chloro-2,3,3-trimethylbutane, 2,3-dibromo-2,3-dimethylbutane and tetra(fluoromethyl)methane. The evaluated correlation times and activation energies for the solids of high entropy of fusion are equivalent to those for self-diffusion as measured by the radiotracer (or plastic deformation) technique. Proceeding to lower entropies of fusion there is a gradually increasing divergence between the 2 sets of data. It is proposed that this variation is a consequence of the way in which the different techniques reflect translational motion in systems with increasing defect disorder.

Molecular Crystals and Liquid Crystals published new progress about 594-81-0. 594-81-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 2,3-Dibromo-2,3-dimethylbutane, and the molecular formula is C6H12Br2, Application of 2,3-Dibromo-2,3-dimethylbutane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Ding, Hairong published the artcileCompeting hydrogen bonding and halogen bonding interactions in crystal engineering: A case study of bi-functional donor molecules, Synthetic Route of 1998-61-4, the publication is Chemical Physics (2014), 30-37, database is CAplus.

Based on the recent determined co-crystals of a set of bi-functional donor mols. with two isomeric sym. acceptors, the competition between hydrogen bonding and halogen bonding interactions in crystal engineering was studied in this work using the M06-2x and ωB97XD methods. The preference of the occurrence of secondary weak interactions was observed in hydrogen-bonded complexes. Hydrogen bonding interactions are predicted to be much stronger than corresponding halogen bonding interactions. No obvious difference was found between the systems of the two acceptors under study. The model complexes, in which hydrogen bonds and halogen bonds coexist, show additivity. Finally, a comparison between theor. results and exptl. observations was presented, and the implications of the calculations on the supermol. assemblies based on the two interactions were also discussed.

Chemical Physics published new progress about 1998-61-4. 1998-61-4 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Benzene,Phenol, name is 4-Bromo-2,3,5,6-tetrafluorophenol, and the molecular formula is C6HBrF4O, Synthetic Route of 1998-61-4.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Li, Lixin published the artcileFacial Syntheses of Bromobenzothiazines via Catalyst-Free Tandem C-H Amination/Bromination in Water, Application In Synthesis of 89694-44-0, the publication is Organic Letters (2019), 21(15), 5995-5999, database is CAplus and MEDLINE.

A transition-metal-free and environmentally friendly synthesis method for bromobenzothiazines through tandem C-H amination/bromination was reported. This reaction contains both intramol. C-H amination and site-selective electrophilic bromination of arenes with NaBr as the bromo source, PhI(OAc)₂ or K₂S₂O₈ as the oxidant, and H₂O as the only solvent.

Organic Letters published new progress about 89694-44-0. 89694-44-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is 2-Bromo-5-methoxybenzene boronic acid, and the molecular formula is C7H8BBrO3, Application In Synthesis of 89694-44-0.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Li, Songyi published the artcileTransition Metal Free Stannylation of Alkyl Halides: The Rapid Synthesis of Alkyltrimethylstannanes, Safety of 1-Bromododecane, the publication is Journal of Organic Chemistry (2022), 87(6), 4291-4297, database is CAplus and MEDLINE.

A transition metal free stannylation reaction of alkyl bromides and iodides with hexamethyldistannane was developed. This protocol is operationally convenient and features a rapid reaction and good functional group tolerance. A wide range of functionalized primary and secondary alkyl and benzyl tri-Me stannanes were prepared in moderate to excellent yields. The success of the gram-scale procedure and tandem Stille coupling reaction has allowed this protocol to demonstrate potential for application in organic synthesis. Both exptl. and theor. studies reveal the mechanistic details of this stannylation reaction.

Journal of Organic Chemistry published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H25Br, Safety of 1-Bromododecane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Li, Ya-Syuan published the artcileCerium(III) triflate-catalyzed cycloaddition reaction in aqueous conditions to substituted naphthotriazolediones, Product Details of C12H25Br, the publication is Journal of the Chinese Chemical Society (Weinheim, Germany) (2022), 69(5), 849-855, database is CAplus.

In this study, the cerium(III) trifluoromethanesulfonate-catalyzed cycloaddition of 1,4-naphthoquinone with functionalized azides in aqueous solutions was used to synthesize naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives Moreover, this method boasts scalability and completes the synthesis of two key biol. compounds This method’s advantages are environmentally friendly reaction conditions, easy applicability in large-scale operations, broad structurally diverse products produced in high yields and the recyclability of catalysts.

Journal of the Chinese Chemical Society (Weinheim, Germany) published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H25Br, Product Details of C12H25Br.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Liu, Lilian Kao published the artcileReaction of aromatic and unsaturated compounds with the potassium permanganate/HCl (HBr) acetonitrile reagent, Computed Properties of 594-81-0, the publication is Journal of the Chinese Chemical Society (Taipei) (1996), 43(1), 61-6, database is CAplus.

Addition of hydrochloric or hydrobromic acid to a solution of potassium permanganate in acetonitrile produced a homogeneous mixture, which is suitable for laboratory chlorination or bromination, resp. Aromatic compounds more reactive than alkylbenzenes can be chlorinated or brominated without addnl. catalyst. Alkenes and alkynes give the corresponding vicinal dihaloalkanes and vinyl halides. All reactions complete within two hours under mild condition (25-60°) with excellent to moderate yields.

Journal of the Chinese Chemical Society (Taipei) published new progress about 594-81-0. 594-81-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 2,3-Dibromo-2,3-dimethylbutane, and the molecular formula is C6H12Br2, Computed Properties of 594-81-0.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Zhang, Xiaoyi published the artcileTetraphenylethylene-rufigallol-tetraphenylethylene trimers: Novel fluorescence liquid crystals in aggregated states, Related Products of bromides-buliding-blocks, the publication is Journal of Molecular Structure (2022), 131643, database is CAplus.

This work reported two novel liquid crystals with good fluorescence in aggregated states. Two tetraphenylethylene-rufigallol-tetraphenylethylene trimers were prepared in simple procedure. The columnar liquid crystalline behaviors of compound I [R = pentyl, dodecyl] were confirmed by the anal. of differential scanning calorimetry, polarizing optical microscopy and X-ray diffraction. Compound I [R = dodecyl] exhibited an ordered hexagonal columnar mesophase. They possessed excellent AIE fluorescence properties in THF-H₂O solution, solid film and mesophase. The fluorescence quantum yields of compounds I were 12% and 22% in solid films, 14% and 24% in mesophase, resp. The exptl. results showed that the liquid crystalline properties and fluorescence properties were tuned by the lengths of the terminal alkyl chains.

Journal of Molecular Structure published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C7H8O3, Related Products of bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Negishi, Ei-ichi published the artcileA Novel, Highly Selective, and General Methodology for the Synthesis of 1,5-Diene-Containing Oligoisoprenoids of All Possible Geometrical Combinations Exemplified by an Iterative and Convergent Synthesis of Coenzyme Q₁₀, Recommanded Product: (4-Bromobut-1-yn-1-yl)trimethylsilane, the publication is Organic Letters (2002), 4(2), 261-264, database is CAplus and MEDLINE.

A truly general, versatile, and highly regio- and stereoselective methodol. for the synthesis of terpenoids containing 1,5-diene units of E and/or Z geometry critically involves Pd-catalyzed homoallyl- and homopropargyl-alkenyl coupling and Zr-catalyzed carboalumination of alkynes. By using this methodol., coenzyme Q₁₀ (I), (E,Z,E)-geranylgeraniol (II), and other natural or unnatural compounds have been synthesized efficiently.

Organic Letters published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Recommanded Product: (4-Bromobut-1-yn-1-yl)trimethylsilane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary