Tag: M.W=200-250

Kuznetsova, Darya A. published the artcileCationic Imidazolium Amphiphiles Bearing a Methoxyphenyl Fragment: Synthesis, Self-Assembly Behavior, and Antimicrobial Activity, Recommanded Product: 1-Bromododecane, the publication is Langmuir (2022), 38(16), 4921-4934, database is CAplus and MEDLINE.

Novel cationic amphiphiles of the 3-alkyl-1-(4-methoxyphenyl)-1H-imidazol-3-ium bromide series bearing methoxyphenyl fragments (MPI-n) have been synthesized. Their aggregation properties in aqueous solutions, solubilization capacity, and hemolytic and antimicrobial activities have been investigated by a number of physicochem. methods. Using tensiometry, conductometry, and fluorescence spectroscopy, it was shown that the MPI-n have lower CMCs than their nonfunctionalized counterparts. The unusual alkyl-chain-length-dependent morphol. of aggregates is testified for this homol. series. Amphiphiles with 12, 14, and 16 alkyl tails are characterized by the formation of micellar aggregates, while a surfactant with a decyl tail is characterized by the formation of larger aggregates with lower surface curvature. The MPI-10 aggregate morphol. was rationalized in terms of the packing parameter consideration and was supported by size measurements and the fluorescence probe techniques, which showed that vesicle-like aggregates in close-packing mode probably occur. MPI-n aggregates have exhibited a high solubilization capacity toward hydrophobic azo dye Orange OT. Importantly, amphiphiles studied showed (i) high bacteriostatic activity at the level of ciprofloxacin; (ii) high bactericidal action against all Gram-pos. bacteria, including methicillin-resistant strains; (iii) bactericidal properties against Gram-neg. bacteria; and (iv) low hemolytic activity.

Langmuir published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H25Br, Recommanded Product: 1-Bromododecane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Kuznetsova, Lidia I. published the artcileOxidative Bromination of Alkenes Mediated with Nitrite in Ionic Liquids, Recommanded Product: 2,3-Dibromo-2,3-dimethylbutane, the publication is Catalysis Letters (2014), 144(9), 1499-1506, database is CAplus.

An oxidative bromination of C₂-C₈ alkenes with HBr-NaNO₂-O₂ in solutions of BMImBr, HMImBr or BMImBF₄ containing 16-28 wt% H₂O was studied using a volumetric method, GC-MS anal., ¹⁴N NMR and UV-VIS spectroscopy. The optimal conditions to conduct the reaction at high selectivity for 1,2-dibromoalkanes in BMImBr were determined The composition of ionic liquid affects the catalytic performance. Although in BMImBF₄ the reaction runs with equal rate as in bromide ionic liquid, the fraction of bromohydrin in the reaction products increases to 20%. Generated from NaNO₂, NO_x operated as a catalyst in the oxidation of bromide ion (Br^–) and was oxidized to catalytically inert nitrate (NO₃^–) anions when complete conversion of HBr was attained. The synthesis of the target compounds was achieved using 1-butyl-3-methylimidazolium bromide as ionic liquid Alkenes included 1-propene, 1-butene (α-alkenes), 2-methyl-1-propene, cyclohexene, 1-octene, 2,3-dimethyl-2-butene. The title compounds thus formed included 1,2-dibromopropane, 1,2-dibromobutane, 1,2-dibromo-2-methylpropane and similar substances. Alcs., such as 1-bromo-2-propanol, 1-bromo-2-butanol, 1-bromo-2-methyl-2-propanol, 2-bromocyclohexanol, 1-bromo-2-octanol, 2-bromoethanol were also observed Formation of 2,3-dimethyl-2,3-dinitrobutane and 2,2,3,3-tetramethyloxirane was reported.

Catalysis Letters published new progress about 594-81-0. 594-81-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 2,3-Dibromo-2,3-dimethylbutane, and the molecular formula is C6H12Br2, Recommanded Product: 2,3-Dibromo-2,3-dimethylbutane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Levitz, Andrew published the artcileSynthesis and effect of heterocycle modification on the spectroscopic properties of a series of unsymmetrical trimethine cyanine dyes, Name: Sodium 3-bromopropane-1-sulfonate, the publication is Dyes and Pigments (2014), 238-249, database is CAplus.

Carbocyanine dyes are a class of organic compounds that contain two heterocycles that act as electron donors and acceptors connected by a conjugated methine bridge. Herein the synthesis of a series of 16 novel unsym. trimethine cyanine dyes is reported. Their structures were characterized by various spectroscopic techniques, and their optical properties were measured. Absorption maxima of the dyes were calculated using the time-dependent d.-functional theory method and the computational absorption maxima are consistent with the exptl. data. The addition of electron withdrawing substituents such as halogens on the heterocycle gave more favorable optical properties such as higher quantum yield and molar absorptivity. The aggregation of these cyanine dyes was studied and compared to a similar series of sym. cyanine dyes. It was determined that the heterocycle has more effect on aggregation than the side chain and a dye with two different heterocycles will aggregate less than a dye with the same heterocycle. The dyes were also investigated for Lipinski Rule violations as their use is becoming more prevalent for in vivo applications.

Dyes and Pigments published new progress about 55788-44-8. 55788-44-8 belongs to bromides-buliding-blocks, auxiliary class Bromide,Salt,Aliphatic hydrocarbon chain,Aliphatic hydrocarbon chain, name is Sodium 3-bromopropane-1-sulfonate, and the molecular formula is C3H6BrNaO3S, Name: Sodium 3-bromopropane-1-sulfonate.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Cleveland, Forrest F. published the artcileSubstituted ethanes. II. Raman and infrared spectra of 2,3-dibromo-2,3-dimethylbutane, 2,2,3,3-tetramethylbutane, Product Details of C6H12Br2, the publication is Journal of Chemical Physics (1950), 1320-4, database is CAplus.

cf. C.A. 39, 2254.3. Raman displacements and infrared absorption wave numbers for 2,3-dibromo-2,3-dimethylbutane and 2,2,3,3-tetramethylbutane (hexamethylethane) are reported, together with depolarization factors for the Raman lines and relative intensities for both the Raman lines and the infrared absorption bands. The spectra were obtained in both benzene and CCl₄ solutions and the infrared measurements covered the region 400-5000 cm^-1. The results indicate that both mols. possess a center of symmetry and that the structure is the same in the two solvents. The dipole moment of 1.01 D. obtained by Mizushima, Morino, and Miyagawa (private communication) for 2,3-dibromo-2,3-dimethylbutane in CCl₄ solution can be explained by oscillations of 48° amplitude about the equilibrium trans position. Cf. C.A. 38, 3908.7.

Journal of Chemical Physics published new progress about 594-81-0. 594-81-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 2,3-Dibromo-2,3-dimethylbutane, and the molecular formula is C6H12Br2, Product Details of C6H12Br2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Carrera, Elisa I. published the artcileA Mechanistic Study of Halogen Addition and Photoelimination from π-Conjugated Tellurophenes, Application In Synthesis of 594-81-0, the publication is Journal of the American Chemical Society (2016), 138(8), 2678-2689, database is CAplus and MEDLINE.

The ability to drive reactivity using visible light is of importance for many disciplines of chem. and has significant implications for sustainable chem. Identifying photochem. active compounds and understanding photochem. mechanisms is important for the development of useful materials for synthesis and catalysis. Here we report a series of photoactive diphenyltellurophene compounds bearing electron-withdrawing and electron-donating substituents synthesized by alkyne coupling/ring closing or palladium-catalyzed ipso-arylation chem. The redox chem. of these compounds was studied with respect to oxidative addition and photoelimination of bromine, which is of importance for energy storage reactions involving X₂. The oxidative addition reaction mechanism was studied using d. functional theory, the results of which support a three-step mechanism involving the formation of an initial η¹ association complex, a monobrominated intermediate, and finally the dibrominated product. All of the tellurophene derivatives undergo photoreduction using 430, 447, or 617 nm light depending on the absorption properties of the compound Compounds bearing electron-withdrawing substituents have the highest photochem. quantum efficiencies in the presence of an alkene trap, with efficiencies of up to 42.4% for a pentafluorophenyl-functionalized tellurophene. The photoelimination reaction was studied in detail through bromine trapping experiments and laser flash photolysis, and a mechanism is proposed. The photoreaction, which occurs by release of bromine radicals, is competitive with intersystem crossing to the triplet state of the brominated species, as evidenced by the formation of singlet oxygen. These findings should be useful for the design of new photochem. active compounds supported by main-group elements.

Journal of the American Chemical Society published new progress about 594-81-0. 594-81-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 2,3-Dibromo-2,3-dimethylbutane, and the molecular formula is C6H12Br2, Application In Synthesis of 594-81-0.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Dickner, Tim published the artcileStereoselective synthesis and binding properties of novel concave-shaped indolizino[3,4-b]quinolines, Product Details of C7H13BrSi, the publication is Journal fuer Praktische Chemie (Weinheim, Germany) (2000), 342(8), 804-811, database is CAplus.

Novel all-cis-configurated indolizino[3,4-b]quinoline receptors I [R = Me, R¹ = H, Ph(CH₂)₃O; R² = H, PhNHCO] were prepared via diastereoselective Lewis acid-catalyzed cyclization of N-arylimines II as a key step. In order to obtain the indolizino[3,4-b]quinoline I (R = R² = H; R¹ = Cl), an N-arylimine precursor II (III; R = Me₃Si; R¹ = Cl; R² = H) was prepared in 8 steps from L-prolinol. In contrast to the known β-effect of silyl groups, cyclization of III proceeded via α-carbenium ion species to give the diastereomeric products I (R = Me₃Si; R¹ = Cl; R² = H), which were desilylated to I (R = R² = H; R¹ = Cl). The association constants for receptors I decreased in the order I (R = R² = H; R¹ = Cl) > I (R = Me; R¹ = R² = H) > I (R= Me; R¹ = H; R² = PhNHCO) > I [R = Me; R¹ = Ph(CH₂)₃O; R² = H] for both acetic acid and N-Z-phenylalanine as substrates.

Journal fuer Praktische Chemie (Weinheim, Germany) published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Product Details of C7H13BrSi.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Miclotte, Matthieu P. J. published the artcileTuning the Cloud-Point and Flocculation Temperature of Poly(2-(diethylamino)ethyl methacrylate)-Based Nanoparticles via a Postpolymerization Betainization Approach, Synthetic Route of 55788-44-8, the publication is ACS Polymers Au (2021), 1(1), 47-58, database is CAplus and MEDLINE.

The ability to tune the behavior of temperature-responsive polymers and self-assembled nanostructures has attracted significant interest in recent years, particularly in regard to their use in biotechnol. applications. Herein, well-defined poly(2-(diethylamino)ethyl methacrylate) (PDEAEMA)-based core-shell particles were prepared by RAFT-mediated emulsion polymerization, which displayed a lower-critical solution temperature (LCST) phase transition in aqueous media. The tertiary amine groups of PDEAEMA units were then utilized as functional handles to modify the core-forming block chem. via a postpolymn. betainization approach for tuning both the cloud-point temperature (T_CP) and flocculation temperature (T_CFT) of these particles. In particular, four different sulfonate salts were explored aiming to investigate the effect of the carbon chain length and the presence of hydroxyl functionalities alongside the carbon spacer on the particle’s thermoresponsiveness. In all cases, it was possible to regulate both T_CP and T_CFT of these nanoparticles upon varying the degree of betainization. Although T_CP was found to be dependent on the type of betainization reagent utilized, it only significantly increased for particles betainized using sodium 3-chloro-2-hydroxy-1-propanesulfonate, while varying the aliphatic chain length of the sulfobetaine only provided limited temperature variation. In comparison, the onset of flocculation for betainized particles varied over a much broader temperature range when varying the degree of betainization with no real correlation identified between T_CFT and the sulfobetaine structure. Moreover, exptl. results were shown to partially correlate to computational oligomer hydrophobicity calculations Overall, the innovative postpolymn. betainization approach utilizing various sulfonate salts reported herein provides a straightforward methodol. for modifying the thermoresponsive behavior of soft polymeric particles with potential applications in drug delivery, sensing, and oil/lubricant viscosity modification.

ACS Polymers Au published new progress about 55788-44-8. 55788-44-8 belongs to bromides-buliding-blocks, auxiliary class Bromide,Salt,Aliphatic hydrocarbon chain,Aliphatic hydrocarbon chain, name is Sodium 3-bromopropane-1-sulfonate, and the molecular formula is C3H6BrNaO3S, Synthetic Route of 55788-44-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Raphael Karikachery, Alice published the artcileHigh Quantum Yield Molecular Bromine Photoelimination from Mononuclear Platinum(IV) Complexes, Recommanded Product: 2,3-Dibromo-2,3-dimethylbutane, the publication is Inorganic Chemistry (2013), 52(7), 4113-4119, database is CAplus and MEDLINE.

Pt(IV) complexes trans-Pt(PEt₃)₂(R)(Br)₃ (R = Br, aryl and polycyclic aromatic fragments) photoeliminate mol. bromine with quantum yields as high as 82%. Photoelimination occurs both in the solid state and in solution Calorimetry measurements and DFT calculations (PMe₃ analogs) indicate endothermic and endergonic photoeliminations with free energies from 2 to 22 kcal/mol of Br₂. Solution trapping experiments with high concentrations of 2,3-dimethyl-2-butene suggest a radical-like excited state precursor to bromine elimination.

Inorganic Chemistry published new progress about 594-81-0. 594-81-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 2,3-Dibromo-2,3-dimethylbutane, and the molecular formula is C6H12Br2, Recommanded Product: 2,3-Dibromo-2,3-dimethylbutane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Harrison, Tyler J. published the artcilePyrrole Synthesis Catalyzed by AgOTf or Cationic Au(I) Complexes, Application In Synthesis of 69361-41-7, the publication is Journal of Organic Chemistry (2006), 71(12), 4525-4529, database is CAplus and MEDLINE.

Either silver trifluoromethanesulfonate or a mixture of gold(I) chloride, silver trifluoromethanesulfonate, and triphenylphosphine catalyze the formation of pyrroles from substituted β-alkynyl ketones and amines. The reactions proceed by using 5 mol % of catalyst with yields of isolated pyrroles ranging from 13% to 92%. Sixteen examples are used to compare the effectiveness of each catalyst. Example compounds thus prepared included also cyclopenta[b]pyrrole derivatives tetrahydro(methyl)indolizine. and dihydro-1H-pyrrolizine derivatives

Journal of Organic Chemistry published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Application In Synthesis of 69361-41-7.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Sun, Jianwei published the artcileBronsted Acid-Promoted Cyclizations of 1-Siloxy-1,5-diynes, COA of Formula: C7H13BrSi, the publication is Journal of the American Chemical Society (2005), 127(39), 13512-13513, database is CAplus and MEDLINE.

The 1st HNTf₂-promoted 5-endo-dig cyclizations of 1-siloxy-1,5-diynes was developed, which proceed with concomitant formation of C-Hal bonds as a result of halide abstraction from a halocarbon by the intermediate alkenyl cation. E.g., reaction of RCH₂CCCH₂CH₂CCOTIPS (OTIPS = triisopropylsilanolato, R = n-C₇H₁₅) with HNTf₂/CH₂Cl₂ at -78° and allowed to warm to room temperature to give 70% yield of 2-(1-chloro-2-R-ethylidene)cyclopentanone. This process is enabled by a chemoselective activation of the more electron-rich siloxy alkyne moiety of the diyne cyclization precursor and represents an efficient and highly diastereoselective method for assembly of a range of β-halo enones.

Journal of the American Chemical Society published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C6H5F4NO3S, COA of Formula: C7H13BrSi.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary