Tag: M.W=200-250

Qi, Zhigang published the artcileSynthesis and characterization of acid-base polyimides bearing pendant sulfoalkoxy groups for direct methanol fuel cell applications, Product Details of C3H6BrNaO3S, the publication is Journal of Applied Polymer Science (2015), 132(29), 42238/1-42238/8, database is CAplus.

A series of acid-base polyimides with sulfonic acid groups in the side chains have been prepared, based on a new synthesized sulfonated diamine monomer containing pyridine functional group. The effect of the introduction of pyridine groups into copolymer backbone on the properties of membrane were evaluated through the investigation of membrane parameters. The copolymers produced flexible, tough, and transparent membranes by solvent casting method. All the prepared membranes displayed high thermal stability, great oxidative stability and good mech. properties. They exhibited appropriate water uptake (15.8-30.2 wt % at 80°C) and remarkable dimensional stability (2.5-6.9% at 80°C). The proton conductivity of SPI-80 was 1.01 × 10^-2 S cm^-1 at room temperature Moreover, the methanol permeability of SPI-80 membrane was 1.22 × 10^-7 cm² s^-1, which was lower than 23.8 × 10^-7 cm² s^-1 of Nafion 117. Therefore, these acid-base polyimides materials have a promising prospect for direct methanol fuel cell applications. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 42238.

Journal of Applied Polymer Science published new progress about 55788-44-8. 55788-44-8 belongs to bromides-buliding-blocks, auxiliary class Bromide,Salt,Aliphatic hydrocarbon chain,Aliphatic hydrocarbon chain, name is Sodium 3-bromopropane-1-sulfonate, and the molecular formula is C3H6BrNaO3S, Product Details of C3H6BrNaO3S.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Zhegalova, Natalia G. published the artcileSynthesis of nitric oxide probes with fluorescence lifetime sensitivity, Quality Control of 53484-26-7, the publication is Organic & Biomolecular Chemistry (2013), 11(47), 8228-8234, database is CAplus and MEDLINE.

The authors present the rationale, synthesis and evaluation of the 1st activatable fluorescent probe that uses fluorescence lifetime change for detection of nitric oxide. The new probe I (R = R’ = H) features a near-IR polymethine skeleton with a diaminobenzene functionality incorporated into the meso-position. The probe is partially quenched, and upon reaction with nitric oxide shows an increase in the fluorescence lifetime from 1.08 ns to 1.24 ns.

Organic & Biomolecular Chemistry published new progress about 53484-26-7. 53484-26-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Nitro Compound,Amine,Benzene, name is 4-Bromo-N-methyl-2-nitroaniline, and the molecular formula is C8H7NaO4S, Quality Control of 53484-26-7.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Seath, Ciaran P. published the artcileTandem Chemoselective Suzuki-Miyaura Cross-Coupling Enabled by Nucleophile Speciation Control, Recommanded Product: (3-Bromo-5-methoxyphenyl)boronic acid, the publication is Angewandte Chemie, International Edition (2015), 54(34), 9976-9979, database is CAplus and MEDLINE.

Control of boronic acid speciation is presented as a strategy to achieve nucleophile chemoselectivity in the Suzuki-Miyaura reaction. Combined with simultaneous control of oxidative addition and transmetalation, this enables chemoselective formation of two C-C bonds in a single operation, providing a method for the rapid preparation of highly functionalized carbogenic frameworks.

Angewandte Chemie, International Edition published new progress about 849062-12-0. 849062-12-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is (3-Bromo-5-methoxyphenyl)boronic acid, and the molecular formula is C8H15NO, Recommanded Product: (3-Bromo-5-methoxyphenyl)boronic acid.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Leitner, Christian published the artcileTotal synthesis of (±)-20S-hydroxy-1,2-dehydro-pseudoaspidospermidine via a C-H activation/transannular cyclization strategy, Quality Control of 69361-41-7, the publication is Chemical Communications (Cambridge, United Kingdom) (2017), 53(54), 7451-7453, database is CAplus and MEDLINE.

A total synthesis toward the pseudoaspidospermidine family via a C-H activation/transannular cyclization strategy has been accomplished. The applicability of this approach is showcased in the concise synthesis (ten steps) of (±)-20S-hydroxy-1,2-dehydro-pseudoaspidospermidine (I) starting from known dihydropyridone II. Via a joint synthetic sequence, we were also able to address the related iboga alkaloid (±)-isovelbanamine (III) in nine steps. Key features of this synthesis are a transannular cyclization to generate the pseudoaspidospermidine skeleton (C-H activation) and a Witkop photocyclization reaction providing a 9-membered lactam. It is also worth mentioning that the joint synthetic sequence can be carried out on a multigram scale.

Chemical Communications (Cambridge, United Kingdom) published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Quality Control of 69361-41-7.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Preston, Adam J. published the artcileSynthesis and Selected Reactions of a Bicyclic Sultam Having Sulfur at the Apex Position, Safety of Sodium 3-bromopropane-1-sulfonate, the publication is Journal of Organic Chemistry (2006), 71(17), 6573-6578, database is CAplus and MEDLINE.

A practical synthesis of the bicyclic dienyl sultam I has been developed. The viable route involved several key steps. Of these, ring-closing metathesis, represented by the conversion of II to III, had to be implemented in advance of the assembly of other rings such as is present in IV. The second double bond was best introduced by a bromination-dehydrobromination sequence, the 2-fold loss of HBr being achieved most reliably by the use of tetra-n-butylammonium fluoride in CH₂Cl₂ or DMSO. The direct irradiation of I gave rise to the endo-oriented cyclobutene derivative V. The title diene is not a ready participant in Diels-Alder reactions. When heated with endo-bornyltriazolinedione in Et acetate solution, conversion to a 1:1 mixture of VI and its diastereomer occurred as confirmed by X-ray crystallog. anal. From the mechanistic perspective, this transformation constitutes an interesting example of a stereocontrolled and regioselective [2+2] cycloaddition followed by a vinylcyclobutane-cyclohexene rearrangement. Products V and VI constitute examples of strained sulfonamides featuring a norbornyl-like structural component.

Journal of Organic Chemistry published new progress about 55788-44-8. 55788-44-8 belongs to bromides-buliding-blocks, auxiliary class Bromide,Salt,Aliphatic hydrocarbon chain,Aliphatic hydrocarbon chain, name is Sodium 3-bromopropane-1-sulfonate, and the molecular formula is C3H6BrNaO3S, Safety of Sodium 3-bromopropane-1-sulfonate.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Kulkarni, Bheemashankar A. published the artcileA solid-phase equivalent of van Leusen’s TosMIC, and its application in oxazole synthesis, Quality Control of 243455-57-4, the publication is Tetrahedron Letters (1999), 40(30), 5633-5636, database is CAplus.

Polystyrene-SH resin, prepared from Merrifield resin in two steps, was converted to polystyrene-SO₂-CH₂-NC in three steps. This resin functions as a solid-phase equivalent of p-tolylsulfonylmethyl isocyanide (TosMIC). Thus, reaction with aromatic aldehydes and tetrabutylammonium hydroxide as base yields 5-aryloxazoles.

Tetrahedron Letters published new progress about 243455-57-4. 243455-57-4 belongs to bromides-buliding-blocks, auxiliary class Oxazole,Bromide,Benzene, name is 5-(3-Bromophenyl)oxazole, and the molecular formula is C9H6BrNO, Quality Control of 243455-57-4.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Wilson, Claire M. published the artcileEnantiospecific sp²-sp³ Coupling of ortho- and para-Phenols with Secondary and Tertiary Boronic Esters, COA of Formula: C7H8BBrO3, the publication is Angewandte Chemie, International Edition (2017), 56(51), 16318-16322, database is CAplus and MEDLINE.

The coupling of ortho- and para-phenols with secondary and tertiary boronic esters has been explored. In the case of para-substituted phenols, after reaction of a dilithio phenolate species with a boronic ester, treatment with Ph₃BiF₂ or Martin’s sulfurane gave the coupled product with complete enantiospecificity. The methodol. was applied to the synthesis of the broad spectrum antibacterial natural product (-)-4-(1,5-dimethylhex-4-enyl)-2-methylphenol. For ortho-substituted phenols, initial incorporation of a benzotriazole on the phenol oxygen atom was required. Subsequent ortho-lithiation and borylation gave the coupled product, again with complete stereospecificity.

Angewandte Chemie, International Edition published new progress about 89694-44-0. 89694-44-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is 2-Bromo-5-methoxybenzene boronic acid, and the molecular formula is C19H14N2, COA of Formula: C7H8BBrO3.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Mattarella, Martin published the artcileNanomolar cholera toxin inhibitors based on symmetrical pentavalent ganglioside GM1os-sym-corannulenes, Safety of (4-Bromobut-1-yn-1-yl)trimethylsilane, the publication is Organic & Biomolecular Chemistry (2013), 11(26), 4333-4339, database is CAplus and MEDLINE.

Eight sym. and pentavalent corannulene derivatives were functionalized with galactose and the ganglioside GM1-oligosaccharide (GM1os) via copper-catalyzed alkyne-azide cycloaddition (CuAAC) reactions. The compounds were evaluated for their ability to inhibit the binding of the pentavalent cholera toxin to its natural ligand, ganglioside GM1. In this assay, all ganglioside GM1os-sym-corannulenes proved to be highly potent nanomolar inhibitors of cholera toxin.

Organic & Biomolecular Chemistry published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Safety of (4-Bromobut-1-yn-1-yl)trimethylsilane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Suchaud, Virginie published the artcileIdentification of 1,6-dihydropyrazolo[4,3-c]carbazoles and 3,6-dihydropyrazolo[3,4-c]carbazoles as new Pim kinase inhibitors, Product Details of C7H8BBrO3, the publication is Bioorganic & Medicinal Chemistry (2013), 21(14), 4102-4111, database is CAplus and MEDLINE.

New 1,6-dihydropyrazolo[4,3-c]carbazoles and 3,6-dihydropyrazolo[3,4-c]carbazoles were prepared and evaluated for their Pim kinase inhibitory potencies as well as their antiproliferative activities toward two prostatic cancer cell lines. Pyrazolocarbazole I was found to be a potent Pim kinase modulator with inhibitory potency toward the three isoforms. Compound II strongly inhibited Pim-3 with weaker effects toward Pim-1 and Pim-2, and thus could be used as an interesting mol. tool to study Pim-3 biol. functions.

Bioorganic & Medicinal Chemistry published new progress about 89694-44-0. 89694-44-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is 2-Bromo-5-methoxybenzene boronic acid, and the molecular formula is C13H17BrO3, Product Details of C7H8BBrO3.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Grollier, Kevin published the artcileElectrochemical Trifluoromethylselenolation of Activated Alkyl Halides, Recommanded Product: 1-Bromododecane, the publication is European Journal of Organic Chemistry (2022), 2022(19), e202200123, database is CAplus.

A practical electrochem. method for the generation of CF₃Se^– anion from a shelf-stable reagent (TsSeCF₃) is reported allowing the metal-free trifluoromethylselenolation of activated alkyl halides RCH₂X (X = Br, Cl; R = 4-F-Ph, pyridin-2-yl, 5-nitrofuran-2-yl, undecyl, etc.). Trifluoromethylselenolated compounds RCH₂SeCF₃ have been obtained in modest to excellent yields under the optimized reaction conditions. Finally, cyclic voltammetric and ¹⁹F NMR studies are presented and allowed to gain insight into the reaction mechanism.

European Journal of Organic Chemistry published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H25Br, Recommanded Product: 1-Bromododecane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary