Tag: M.W=200-250

Woerly, Eric M. published the artcileEnantioselective, Catalytic Fluorolactonization Reactions with a Nucleophilic Fluoride Source, Recommanded Product: Methyl 2-bromo-3-fluorobenzoate, the main research area is fluoroisochromanone enantioselective synthesis regioselectivity; alkenyl benzoate preparation fluorolactonization; bromobenzoate alkenyl boronic acid pinacol ester.

The enantioselective synthesis of 4-fluoroisochromanones via chiral aryl iodide-catalyzed fluorolactonization is reported. This methodol. uses HF-pyridine as a nucleophilic fluoride source with a peracid stoichiometric oxidant and provides access to lactones containing fluorine-bearing stereogenic centers in high enantio- and diastereoselectivity. The regioselectivity observed in these lactonization reactions is complementary to that obtained with established asym. electrophilic fluorination protocols.

Journal of the American Chemical Society published new progress about Enantioselective synthesis. 647020-71-1 belongs to class bromides-buliding-blocks, name is Methyl 2-bromo-3-fluorobenzoate, and the molecular formula is C8H6BrFO2, Recommanded Product: Methyl 2-bromo-3-fluorobenzoate.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zhao, Nan published the artcileAsymmetric total synthesis of (+)-astellatol and (-)-astellatene, Related Products of bromides-buliding-blocks, the main research area is astellatol enantioselective preparation; astellatene enantioselective preparation.

The synthesis of (+)-astellatol, as well as the first total synthesis of (-)-astellatene was described. This work highlights a mercury(II)-catalyzed Grignard reaction, an intramol. Pauson-Khand reaction, a samarium(II)-mediated reductive radical 1,6-addition and a novel strategy for the synthesis of highly substituted trans-hydrindane natural products.

Organic Chemistry Frontiers published new progress about Enantioselective synthesis. 74317-85-4 belongs to class bromides-buliding-blocks, name is 2-Bromo-4-methoxybenzoic acid, and the molecular formula is C8H7BrO3, Related Products of bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Joshi-Pangu, Amruta published the artcileAcridinium-Based Photocatalysts: A Sustainable Option in Photoredox Catalysis, Category: bromides-buliding-blocks, the main research area is acridinium photoredox catalysis redox potential.

The emergence of visible light photoredox catalysis has enabled the productive use of lower energy radiation, leading to highly selective reaction platforms. Polypyridyl complexes of iridium and ruthenium have served as popular photocatalysts in recent years due to their long excited state lifetimes and useful redox windows, leading to the development of diverse photoredox-catalyzed transformations. The low abundances of Ir and Ru in the earth’s crust and, hence, cost make these catalysts nonsustainable and have limited their application in industrial-scale manufacturing Herein, we report a series of novel acridinium salts as alternatives to iridium photoredox catalysts and show their comparability to the ubiquitous [Ir(dF-CF3-ppy)2(dtbpy)](PF6).

Journal of Organic Chemistry published new progress about Half wave potential, redox. 74317-85-4 belongs to class bromides-buliding-blocks, name is 2-Bromo-4-methoxybenzoic acid, and the molecular formula is C8H7BrO3, Category: bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Humphrey, Guy R. published the artcileA novel synthesis of 3-bromo-1,2,4-oxadiazoles, Recommanded Product: 3-Bromo-5-phenyl-1,2,4-oxadiazole, the main research area is dipolar cycloaddition bromocyanogen oxide nitrile; bromoxadiazole.

The synthesis of 3-bromo-1,2,4-oxadiazoles I (R = Me2CH, cyclopropyl, EtO2C, PhCH2, Ph, 4-O2NC6H4, ClCH2, BrCH2) by 1,3-dipolar cycloaddition between BrCNO and RCN (same R) is described. Thus, Br2C:NOH in PhCN was treated with NaHCO3 to give 40% I (R = Ph) along with a small amount of the dimer II.

Journal of Heterocyclic Chemistry published new progress about 1,3-Dipolar cycloaddition reaction. 23432-94-2 belongs to class bromides-buliding-blocks, name is 3-Bromo-5-phenyl-1,2,4-oxadiazole, and the molecular formula is C8H5BrN2O, Recommanded Product: 3-Bromo-5-phenyl-1,2,4-oxadiazole.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Saccone, Marco published the artcileImproving the mesomorphic behaviour of supramolecular liquid crystals by resonance-assisted hydrogen bonding, Synthetic Route of 84743-77-1, the main research area is supramol liquid crystal preparation hydrogen bonding mesomorphic behavior.

A systematic structure-property relationship study on hydrogen-bonded liquid crystals was performed, revealing the impact of resonance-assisted hydrogen bonds (RAHBs) on the self-assembling behavior of the supramol. architecture. The creation of a six-membered intramol. hydrogen-bonded ring acts as a counterpart to the self-organization between hydrogen bond donators and acceptors and determines thus the suprastructure. Variation of the hydrogen-bonding pattern allowed us to significantly improve the temperature range of the reported liquid crystalline assemblies.

Journal of Materials Chemistry C: Materials for Optical and Electronic Devices published new progress about Hydrogen bond (resonance-assisted). 84743-77-1 belongs to class bromides-buliding-blocks, name is 2-Bromobenzene-1,3,5-triol, and the molecular formula is C6H5BrO3, Synthetic Route of 84743-77-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dethe, Dattatraya H. published the artcileAsymmetric Ru/Cinchonine Dual Catalysis for the One-Pot Synthesis of Optically Active Phthalides from Benzoic Acids and Acrylates, Product Details of C8H7BrO3, the main research area is phthalide enantioselective preparation; benzoic acid acrylate ruthenium cinchonine tandem CH activation Michael.

Herein, asym. Ru/cinchonine dual catalysis that provided straightforward access to enantioselective synthesis of C-3 substituted phthalides, e.g., I via tandem C-H activation/Michael addition was reported. The use of readily accessible and less expensive [RuCl2 (p-cym)]2 and cinchonine catalyst for the one-pot assembly of chiral phthalides greatly overcame the present trend of using highly sophisticated catalysts. The developed method provided access to both enantiomers of a product using pseudo enantiomeric cinchona alkaloids as catalysts streamlining the synthesis of phthalide in both the optically active forms.

Journal of Organic Chemistry published new progress about Benzoic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 74317-85-4 belongs to class bromides-buliding-blocks, name is 2-Bromo-4-methoxybenzoic acid, and the molecular formula is C8H7BrO3, Product Details of C8H7BrO3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Kulyabin, Pavel S. published the artcileMultisubstituted C2-symmetric ansa-metallocenes bearing nitrogen heterocycles: influence of substituents on catalytic properties in propylene polymerization at higher temperatures, SDS of cas: 880652-93-7, the main research area is ansa zirconocene carbazolyl preparation stereoisomer catalyst propylene polymerization; Buchwald Hartwig amination preparation carbazolyl ansa zirconocene polymerization catalyst; electrophilic amination cyclization preparation carbazolyl ansa zirconocene polymerization catalyst.

In this work we systematically studied the effects of modifications of substituents on the performance of the isospecific zirconocene-based catalyst family, Me2Si(2-Alk-4-(N-carbazolyl)Ind)ZrX2 (X = Cl, Me), wherein the progenitor was shown to be particularly suitable in high-temperature propylene polymerization processes. In order to obtain the required zirconocenes, we developed a novel synthetic pathway to 4-(N-carbazolyl)indenes through Pd-catalyzed cyclizations of 2,2′-dibromobiaryls with 4-aminoindenes, which were synthesized via Buchwald-Hartwig reaction or electrophilic amination of 4-indenyl Grignard reagents with trimethylsilylmethyl azide. By a number of examples, the anion-promoted rac-to-meso isomerization method was shown to work reliably well for preparation of rac-ZrMe2-complexes. Certain zirconocenes among the 21 tested in propylene polymerization at 70-100° under MAO or borate activation outperformed the parent catalyst in mol. weight capability, regio- or stereoselectivity.

Dalton Transactions published new progress about Aluminoxanes, Me Role: CAT (Catalyst Use), USES (Uses) (MAO). 880652-93-7 belongs to class bromides-buliding-blocks, name is 7-Bromo-2-methyl-1H-indene, and the molecular formula is C10H9Br, SDS of cas: 880652-93-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Wang, Qian published the artcileIsoquinolone-4-Carboxylic Acids by Ammonia-Ugi-4CR and Copper-Catalyzed Domino Reaction, Category: bromides-buliding-blocks, the main research area is carboxy isoquinolone preparation green chem; benzoylaminoacetamide preparation green chem keto ester heterocyclization copper catalyst; halobenzoic acid aldehyde isocyanide ammonia multicomponent Ugi reaction.

Highly substituted isoquinolone-4-carboxylic acid I (R1 = H, 7-Me, 6-OMe, 6-NO2, etc.; R2 = H, Me, cyclopentyl, Ph, etc.; R3 = tert-Bu, 2-ethylphenyl, cyclopropylmethyl, benzyl, etc.; R4 = Me, iso-Pr, Pr, phenyl) is an important bioactive scaffold; however, it is challenging to access it in a general and short way. A Cu-catalyzed cascade reaction was successfully designed involving the Ugi postcyclization strategy by using ammonia and 2-halobenzoic acids 2-X-(R5)C6H3C(O)OH (R5 = H, 4-OMe, 5-Me, etc.; X = Br, I) as crucial building blocks. Privileged polysubstituted isoquinolin-1(2H)-ones I were constructed in a combinatorial format with generally moderate to good yields. The protocol, with a ligand-free catalytic system, shows a broad substrate scope and good functional group tolerance toward excellent mol. diversity. Free 4-carboxy-isoquinolone is now for the first time generally accessible by a convergent multicomponent reaction protocol.

Journal of Organic Chemistry published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 74317-85-4 belongs to class bromides-buliding-blocks, name is 2-Bromo-4-methoxybenzoic acid, and the molecular formula is C8H7BrO3, Category: bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Wang, Qian published the artcileCopper-Catalyzed Modular Assembly of Polyheterocycles, Name: 2-Bromo-4-methoxybenzoic acid, the main research area is indenoisoquinolinone preparation; indenedione benzamide preparation cyclization copper catalyst; carboxylic acid isocyanide aldehyde ammonia Ugi reaction.

Easy operation, readily accessible starting materials, and short synthesis of the privileged scaffold indeno[1,2-c]isoquinolinones I (R1 = H, 3-MeO, 2-Me, 2-NO2, etc.; R2 = H, Me, cyclopentyl, 4-chlorophenyl, etc.; R3 = tert-Bu, benzyl, 2-methoxy-2-oxoethyl, 2-ethylphenyl, etc.; R4 = H, 8,9-dimethoxy) were achieved by an multicomponent reaction (MCR)-based protocol via an ammonia-Ugi-four component reaction (4CR)/copper-catalyzed annulation sequence. The optimization and scope and limitations of this short and general sequence are described. The methodol. allows an efficient construction of a wide variety of indenoisoquinolinones I in just two steps.

Journal of Organic Chemistry published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 74317-85-4 belongs to class bromides-buliding-blocks, name is 2-Bromo-4-methoxybenzoic acid, and the molecular formula is C8H7BrO3, Name: 2-Bromo-4-methoxybenzoic acid.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yu, Lin published the artcileFe3O4 nanoparticle-supported copper(I): magnetically recoverable and reusable catalyst for the synthesis of quinazolinones and bicyclic pyrimidinones, Category: bromides-buliding-blocks, the main research area is quinazolinone bicyclic pyrimidinone preparation; amidine halobenzoic acid bromocycloalkenecarboxylic acid cyclocondensation; ferrous ferric oxide nanoparticle supported copper catalyst.

A highly efficient, easily recoverable and reusable Fe3O4 magnetic nanoparticle-supported Cu(I) catalyst has been developed for the synthesis of quinazolinones I(R1 = H, 6-F, 7-MeO, 8-Me, 7-NO2, R2 = Me, Ph, cyclopropyl)and bicyclic pyrimidinones II(R = Me, Ph, cyclopropyl). In the presence of supported Cu(I) catalyst (10 mol%), amidines reacted with substituted 2-halobenzoic acids and 2-bromocycloalk-1-enecarboxylic acids to generate the corresponding N-heterocycle products in good to excellent yields at room temperature in DMF. In addition, the supported Cu(I) catalyst could be recovered at least 10 times without significant loss of its catalytic activity.

Applied Organometallic Chemistry published new progress about Amidines Role: RCT (Reactant), RACT (Reactant or Reagent). 74317-85-4 belongs to class bromides-buliding-blocks, name is 2-Bromo-4-methoxybenzoic acid, and the molecular formula is C8H7BrO3, Category: bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary