Tag: M.W=200-250

Zhang, Nan published the artcileAlkylated lignin with graft copolymerization for enhancing toughness of PLA, Application of 1-Bromododecane, the publication is Journal of Materials Science (2022), 57(19), 8687-8700, database is CAplus.

A green modification method for effectively enhancing toughness of PLA was established. Herein, alk. lignin (LG) was firstly alkylated with dodecane, and then grafted with lactide (LA). The alkylated lignin-lactide graft copolymer (GLG-g-LA) was obtained via ring-opening polymerization (ROP). GLG-g-LA copolymer can be utilized as a functional filler to toughen polylactic acid (PLA) packaging film. The 31P-NMR of alkylated lignin (GLG) demonstrated that the peak of phenolic hydroxyl groups disappeared completely, while the relative peak intensity of carboxyl hydroxyl groups decreased significantly. The grafting rate of GLG-g-LA copolymer was improved more than twice times compared with lignin-lactide graft copolymer (LG-g-LA). Then LG-g-LA and GLG-g-LA copolymer were mixed with PLA to prepare different PLA composite films via casting method, resp. Particularly, the elongation at break of PLA/GLG-g-LA2 composite film increased to 41.98%, which was more than 20 times higher than PLA. In general, PLA/GLG-g-LA composite film with toughness, excellent UV barrier, water resistance and controllable gas permeation could be used as high-performance and biodegradable materials in packaging field.

Journal of Materials Science published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C5H5ClO2, Application of 1-Bromododecane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Li, Lin published the artcileA Small-Molecule Probe for Selective Profiling and Imaging of Monoamine Oxidase B Activities in Models of Parkinson’s Disease, Product Details of C7H13BrSi, the publication is Angewandte Chemie, International Edition (2015), 54(37), 10821-10825, database is CAplus and MEDLINE.

The design of the first dual-purpose activity-based probe of monoamine oxidase B (MAO-B) is reported. This probe is highly selective towards MAO-B, even at high MAO-A expression levels, and could sensitively report endogenous MAO-B activities by both in situ proteome profiling and live-cell bioimaging. With a built-in imaging module as part of the probe design, the probe was able to accomplish what all previously reported MAO-B imaging probes failed to do thus far: the live-cell imaging of MAO-B activities without encountering diffusion problems.

Angewandte Chemie, International Edition published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Product Details of C7H13BrSi.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Yao, Zhaoyang published the artcilePyrene-Based Dopant-Free Hole-Transport Polymers with Fluorine-Induced Favorable Molecular Stacking Enable Efficient Perovskite Solar Cells, Category: bromides-buliding-blocks, the publication is Angewandte Chemie, International Edition (2022), 61(24), e202201847, database is CAplus and MEDLINE.

A new class of polymeric hole-transport materials (HTMs) are explored by inserting a two-dimensionally conjugated fluoro-substituted pyrene into thiophene and selenophene polymeric chains. The broad conjugated plane of pyrene and “Lewis soft” selenium atoms not only enhance the π-π stacking of HTM mols. greatly but also render a strong interaction with the perovskite surface, leading to an efficient charge transport/transfer in both the HTM layer and the perovskite/HTM interface. Note that fluorine substitution adjacent to pyrene boosts the stacking of HTMs towards a more favorable face-on orientation, further facilitating the efficient charge transport. As a result, perovskite solar cells (PSCs) employing PE10 as dopant-free HTM afford an excellent efficiency of 22.3 % and the dramatically enhanced device longevity, qualifying it among the best PSCs based on dopant-free HTMs.

Angewandte Chemie, International Edition published new progress about 1998-61-4. 1998-61-4 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Benzene,Phenol, name is 4-Bromo-2,3,5,6-tetrafluorophenol, and the molecular formula is C11H10O, Category: bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Wang, En-si published the artcileSynthesis of a new antiviral medicine famciclovir, Product Details of C8H15BrO2, the publication is Jilin Daxue Ziran Kexue Xuebao (2000), 95-98, database is CAplus.

The title compound was prepared with 21 % yield via regioselective alkylation of 2-aminopurine with 5-(2-bromoethyl)-2,2-dimethyl-1,3-dioxan as a pivotal step. The route without highly toxic reagents and high presure and temperature may be applied to industrial production

Jilin Daxue Ziran Kexue Xuebao published new progress about 97845-58-4. 97845-58-4 belongs to bromides-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Bromide, name is 5-(2-Bromoethyl)-2,2-dimethyl-1,3-dioxane, and the molecular formula is C10H14N2O, Product Details of C8H15BrO2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Tao, Jiayu published the artcileTwo asymmetrical perylene diimide derivatives: Synthesis, optical-electrochemical properties and morphologies of self-assembly, Recommanded Product: 1-Bromododecane, the publication is Journal of Solid State Chemistry (2022), 122665, database is CAplus.

In this manuscript, two PDI derivatives I [X = N] and I [X = O] with unsym. N-substitution of amine and ester-bridge were designed and synthesized. These two compounds were characterized by NMR, Fourier transform IR (FT-IR), and high-resolution mass spectrometry (HRMS). The photophys. properties were studied by UV-Vis absorption and fluorescence spectroscopy. Cyclic voltammograms of I [X = N] and I [X = O] were investigated and HOMO and LUMO energy levels of both two PDIs were estimated as -6.2 and -3.9 eV, resp. Thermal properties were also studied by thermogravimetric anal. (TGA) and differential scanning calorimetry (DSC). I [X = N] was assembled into nanotubes while I [X = O] was assembled into nanobelts resp., via a reprecipitation method. I [X = N] and I [X = O] show good potential application in organic devices such as solar cells, organic field-effect transistors (OFETs) and so on.

Journal of Solid State Chemistry published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C13H9FO2, Recommanded Product: 1-Bromododecane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Tang, Yixiao published the artcileBlack-to-transmissive polymer films via electrochemical copolymerization with high-performance electrochromic and supercapacitor bifunction, Recommanded Product: 1-Bromododecane, the publication is Solar Energy Materials & Solar Cells (2022), 111857, database is CAplus.

The black-to-transmissive electrochromic polymer has significant value with practical applications. Integration of electrochromic and supercapacitor bifunctional materials can indicate its capacitor level by visual color change in real-time. In this paper, based on three EDOT derivative monomers were associated to phenanthrocarbazole/benzotriazole/benzothiadiazole, M1, M2 and M3, a novel ternary random copolymer film was successfully prepared by electrochem. copolymerization Since the corresponding homopolymers of three monomers are red, green and blue in the neutral state resp., and their oxidation states are all transparent, therefore the obtained ternary random copolymer films show the black-to-transmissive electrochromic behavior. The copolymer film pCo-2 was prepared via electrochem. copolymerization with suitable monomers feed ratio (1: 1.5: 1 of M1: M2: M3). Benefit from ternary random electrochem. copolymerization, the pCo-2 copolymer displays excellent electrochromic-supercapacitor properties among the similar bifunctional materials, with fast response time, high optical contrast, good cycling stability and large area (volume) specific capacitance. The electrochromic supercapacitor device based on pCo-2//PEDOT can make an LCD run continuously. This work provides an available general approach to realizing black-to-transmissive electrochromism towards electrochromic-supercapacitor bifunctional applications.

Solar Energy Materials & Solar Cells published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C3H6O2, Recommanded Product: 1-Bromododecane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Wang, Wentian published the artcileDesign and Synthesis of TASIN Analogues Specifically Targeting Colorectal Cancer Cell Lines with Mutant Adenomatous Polyposis Coli (APC), SDS of cas: 69361-41-7, the publication is Journal of Medicinal Chemistry (2019), 62(10), 5217-5241, database is CAplus and MEDLINE.

Despite advances in targeted anticancer therapies, there are still no small-mol.-based therapies available that specifically target colorectal cancer (CRC) development and progression, the second leading cause of cancer deaths. We previously disclosed the discovery of truncating adenomatous polyposis coli (APC)-selective inhibitor 1 (TASIN-1), a small mol. that specifically targets colorectal cancer cells lines with truncating mutations in the adenomatous polyposis coli (APC) tumor suppressor gene through inhibition of cholesterol biosynthesis. Here, we report a medicinal chem. evaluation of a collection of TASIN analogs and activity against colon cancer cell lines and an isogenic cell line pair reporting on the status of APC-dependent selectivity. A number of potent and selective analogs were identified, including compounds with good metabolic stability and pharmacokinetic properties. The compounds reported herein represent a first-in-class genotype-selective series that specifically target apc mutations present in the majority of CRC patients and serve as a translational platform toward a targeted therapy for colon cancer.

Journal of Medicinal Chemistry published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C14H26O2, SDS of cas: 69361-41-7.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Coutrot, P. published the artcileDiethyl (chloromagnesio)methanephosphonate. A novel Grignard reagent and its use in organic synthesis, HPLC of Formula: 66197-72-6, the publication is Journal of Organometallic Chemistry (1986), 316(1-2), 13-18, database is CAplus.

(EtO)₂P(O)CH₂MgCl (I) was obtained by an exchange reaction between (EtO)₂P(O)CH₂I and Me₂CHMgCl in THF at -70°. Reactions of I with electrophiles are described, and compared with those of the analogous lithium or copper derivatives E.g. I reacted with PhCHO to give (EtO)₂P(O)CH₂CH(OH)Ph. I is especially reactive towards phenylselenium halides and halogens.

Journal of Organometallic Chemistry published new progress about 66197-72-6. 66197-72-6 belongs to bromides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyl (bromomethyl)phosphonate, and the molecular formula is C5H12BrO3P, HPLC of Formula: 66197-72-6.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Xu, Wei Ming published the artcilePolystyrene-supported benzyl selenide: An efficient reagent for highly stereo-controlled synthesis of substituted olefins, Application of Diethyl (bromomethyl)phosphonate, the publication is Chinese Chemical Letters (2003), 14(4), 335-337, database is CAplus.

Polystyrene-supported benzyl selenide has been prepared This novel reagent was treated with LDA to produce a selenium stabilized carbanion, which reacted with alkyl halide, followed by selenoxide syn-elimination, to give substituted olefins stereospecifically.

Chinese Chemical Letters published new progress about 66197-72-6. 66197-72-6 belongs to bromides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyl (bromomethyl)phosphonate, and the molecular formula is C14H21BO3, Application of Diethyl (bromomethyl)phosphonate.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Zhu, Jing published the artcileSynthesis of 2,3-Dialkylated Tartaric Acid Esters via Visible Light Photoredox-Catalyzed Reductive Dimerization of α-Ketoesters, Computed Properties of 69361-41-7, the publication is ACS Omega (2017), 2(8), 4665-4677, database is CAplus and MEDLINE.

A mild transition-metal-free protocol to prepare 2,3-dialkylated tartaric acid esters has been developed by taking advantage of a visible light photoredox-catalyzed reductive dimerization of α-ketoesters with a combination of an organic dye photocatalyst and a Hantzsch-type 1,4-dihydropyridine hydrogen donor. A broad range of functional groups including cyclopropane, alkene, alkyne, 4-methoxybenzyl ether, acetal, silyl ether, carbamate, cyclic ether, cyclic thioether, bromoalkane, and N-alkoxyphthalimide are well-compatible. By employing the visible light photoredox-catalyzed reductive coupling and the subsequent optical resolution, both enantioenriched diastereomers of 2,3-dialkylated tartaric acid could be acquired conveniently.

ACS Omega published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C24H29N5O3, Computed Properties of 69361-41-7.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary