Tag: M.W=200-300

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Application In Synthesis of 3-Bromo-2-(bromomethyl)propanoic acid, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 41459-42-1, Name is 3-Bromo-2-(bromomethyl)propanoic acid, molecular formula is C4H6Br2O2. In an article, author is Nguyen Thi Lien,once mentioned of 41459-42-1.

An Electrochemical Sensor Based on Gold Nanodendrite/Surfactant Modified Electrode for Bisphenol A Detection

In the present work, we reported the simple way to fabricate an electrochemical sensing platform to detect Bisphenol A (BPA) using galvanostatic deposition of Au on a glassy carbon electrode covered by cetyltrimethylammonium bromide (CTAB). This material (CTAB) enhances the sensitivity of electrochemical sensors with respect to the detection of BPA. The electrochemical response of the modified GCE to BPA was investigated by cyclic voltammetry and differential pulse voltammetry. The results displayed a low detection limit (22 nm) and a linear range from 0.025 to 10 mu m along side with high reproducibility (RSD = 4.9% for seven independent sensors). Importantly, the prepared sensors were selective enough against interferences with other pollutants in the same electrochemical window. Notably, the presented sensors have already proven their ability in detecting BPA in real plastic water drinking bottle samples with high accuracy (recovery range = 96.60%-102.82%) and it is in good agreement with fluorescence measurements.

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The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 941-37-7, Name is 1-Bromo-3,5-dimethyladamantane, SMILES is CC1(C2)CC3(C)CC2(Br)CC(C3)C1, in an article , author is Shan, Naisong, once mentioned of 941-37-7, Product Details of 941-37-7.

Critical Role of Ion Exchange Conditions on the Properties of Network Ionic Polymers

Ionic polymers are important in a wide range of applications and can exhibit widely different properties depending on the ionic species. In the case of single ion conducting polymers, where one charge is attached to the backbone or as a side group, ion exchange is performed to control the mobile species. While the conditions are often specified, the final ion content is not always quantified, and there are no dear criteria for what concentration of salt is needed in the exchange. A series of ammonium network ionic polymers with different precise carbon spacers (C4-C7) between ionic junctions were synthesized as model systems to understand how the ion exchange conditions impact the resultant polymer properties. The initial networks with free bromide anions were exchanged with 1.5, 3, or 10 equiv of lithium bis(trifluoromethane)sulfonimide (LiTFSI) salt in solution. For networks with seven carbons between cross-links, increasing the LiTFSI concentration led to an increase in ion exchange efficiency from 83.6 to 97.6 mol %. At the highest conversion, the C7 network showed a 4 degrees C decrease in glass transition temperature (T-g), a SO degrees C increase in degradation temperature, 12-fold lower water uptake from air, and a greater than 10-fold increase in conductivity at 90 degrees C. These results illustrate that properties such as T-g are less sensitive to residual ion impurities, whereas the conductivity is highly dependent on the final exchange conversion.

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In an article, author is Utami, Diah Tri, once mentioned the application of 109-64-8, Computed Properties of C3H6Br2, Name is 1,3-Dibromopropane, molecular formula is C3H6Br2, molecular weight is 201.8877, MDL number is MFCD00000255, category is bromides-buliding-blocks. Now introduce a scientific discovery about this category.

Co-treatment of Brazilein Enhances Cytotoxicity of Doxorubicin on WiDr Colorectal Cancer Cells Through Cell Cycle Arrest

BACKGROUND: The presence of adverse side effects limits the use of doxorubicin (Dox) despite its cost-effectiveness compared to other chemotherapeutic agents. Brazilein (Be), the major compound of Caesalpinia sappan, performs co-chemotherapeutic potency in several cancer cell lines. This study evaluates the chemosensitizing effects of Be to Dox on colon cancer cell line, WiDr. METHODS: The 3-(4,5-dimethy Ithiazol-2-yl)-2,5-diphenyl-2H-tetrazolirun bromide (MTT) assay was conducted to evaluate the cytotoxic effect of Be and its combination with Dox. The synergistic effect of Be and Dox was examined by using the Combination index (CI) parameter. Cell cycle and apoptosis profiles were done using flow cytometry with propidium iodide (PI)/RNase and Anncxin V staining, respectively. RESULTS: The combination of Dox and Be at half of IC(50 )on WiDr cells showed a synergistic effect with a combination index of 0.4. Analysis of the cell cycle revealed that the combination caused cell cycle termination at the S and G2/M phase. This finding corresponded with the data that single treatment of Dox and Be induced cell cycle arrest at the different phases, namely S and G2/M phase, respectively. However, the combination treatment for 24 hours did not induce apoptosis. This combination should be further clarified as there was a possibility that many cells may underwent permanently arrest that halts to proceed apoptosis. CONCLUSION: Our findings suggested that Be synergizes with Dox to suppress the growth of WiDr cells via cell cycle arrest, hence, Be is potential to be developed as a co-chemotherapeutic agent. Our findings suggested that Be synergizes with Dox to suppress the growth of WiDr cells via cell cycle arrest, hence, Be is potential to be developed as a co-chemotherapeutic agent.

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The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 2746-25-0, Name is 1-(Bromomethyl)-4-methoxybenzene, SMILES is COC1=CC=C(CBr)C=C1, in an article , author is Rocha, Mariana, once mentioned of 2746-25-0, Name: 1-(Bromomethyl)-4-methoxybenzene.

Diethylaminophenyl-based Schiff base Cu(II) and V(IV) complexes: experimental and theoretical studies and cytotoxicity assays

An N,N,O,O donor Schiff base blocking ligand [H2L = 6,6′-((1E,1’E)-(ethane-1,2-diylbis(azaneylylidene))bis(methaneylylidene))bis(3-(diethylamino)phenol), 1] has been used to synthesize mononuclear [CuL]center dot H2O (2) and [VO(L)] (3) complexes. The ligand and complexes have been characterized by elemental, spectral (FTIR and UV-vis) and thermogravimetric analysis. The molecular structures of 1 and 2 have been confirmed by single crystal X-ray diffraction studies. The crystal structure of the ligand (1) indicates that the molecule is sited on a crystallographic inversion centre and the planar conformation of the salicylideneimine moiety is favored by two intramolecular O-HN center dot center dot center dot 1 hydrogen bonds forming S(6) ring motifs. The copper(ii) center in complex 2 is coordinated in a square planar fashion. The presence of an extended pi-system in the complex (two chelate rings and two phenyl rings) facilitates the formation of chelate ring (CR)center dot center dot center dot pi non-covalent interactions. DFT calculations have been performed to explore the energetic features of unconventional CR center dot center dot center dot pi and hydrogen bonding interactions that are observed and described in the solid state of 2. Moreover, we have studied how the energy of the CR center dot center dot center dot pi interaction is influenced by the substituent of the phenyl ring. In addition, the cytotoxic effect of the compounds has been tested against MG-63 (human osteosarcoma), HT-29 (human colorectal) and MCF7 (breast) cancer cell lines using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay.

Interested yet? Read on for other articles about 2746-25-0, you can contact me at any time and look forward to more communication. Name: 1-(Bromomethyl)-4-methoxybenzene.

Electric Literature of 586-77-6, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 586-77-6, Name is 4-Bromo-N,N-dimethylaniline, SMILES is C1=C(N(C)C)C=CC(=C1)Br, belongs to bromides-buliding-blocks compound. In a article, author is Cai, Haoyuan, introduce new discover of the category.

pH-responsive linkages-enabled layer-by-layer assembled antibacterial and antiadhesive multilayer films with polyelectrolyte nanocapsules as biocide delivery vehicles

Application of the polymer capsules as vehicles for antibacterial surface against bacterial infections is restricted by spontaneous leakage and specifically responsive release of antibacterial agents. Herein, we present the integration of pH-responsive nanocapsules as delivery tools for hydrophobic biocide within layer-by-layer (LbL) films utilizing alternating imine linkages as the driving force for assembly, thus enabling the introduction of drug and controlled release. The novel capsules are fabricated by means of electrostatic LbL assembly, namely, tannin acid/chitosan nanocapsules embedded with triclosan@cetyltrimethylammonium bromide micelles (TCS@CTAB/TA/CH). The nanocapsules achieve an excellent pH-responsive activity that the release efficiency of antibacterial agent triclosan (TCS) increases by nearly 61.8% from pH 8 to 4. Subsequently, the smart nanocapsules are alternatively incorporated via imine linkage into the dextran aldehyde (DA) polyelectrolyte multilayers in LbL deposition (denoted as (DA-TCS@CTAB/TA/CH)(n) films). The as-prepared samples are characterized by FTIR, FESEM, TEM, DLS and AFM. Noticeably, the (DA-TCS @CTAB/TA/CH)(20.5) film exhibites optimal pH-responsive activity with release concentration of TCS up to 4.01 mg/L at pH 6. The bacteriostatic percentages of (DA-TCS@CTAB/TA/CH)(20.5) against E. coll. and P. aeruginosa are respectively 99.62% and 97.35% after 24-h incubation at pH 6. Besides, the multilayers are capable of supplying a long-term (30 days) antibacterial property. The self-polishing mechanism of (DA-TCS@CTAB/TA/CH)(n) films is proposed to illuminate the enhanced antibacterial and antiadhesive performances. It seems that the films present a promising way to incorporate biocide to resist bacterial infections and prolong the antimicrobial activity of antibacterial surface.

Electric Literature of 586-77-6, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 586-77-6 is helpful to your research.

Related Products of 506-26-3, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 506-26-3, Name is (6Z,9Z,12Z)-Octadeca-6,9,12-trienoic acid, SMILES is CCCCC/C=CC/C=CC/C=CCCCCC(O)=O, belongs to bromides-buliding-blocks compound. In a article, author is Wang, Chen, introduce new discover of the category.

Lewis acid/base pair as a catalytic system for alpha-stereoselective synthesis of 2-deoxyglycosides through the addition of alcohols to glycals

This report describes the alpha-stereoselective addition of alcohols to glycals promoted by a cooperative Lewis acid/base pair catalytic system composed of B(C6F5)(3) and tetrabutylammonium bromide (TBAB), which provides access to 2-deoxylglycosides in high yields. A mechanistic investigation supported by NMR analysis highlights the possible involvement of nucleophilic addition through boron-induced activation of alcohols under the assistance of TBAB. The protocol discussed here features the high stereoselectivity, mild reaction conditions, inexpensive and stable catalysts, and a broad substrate scopes. (C) 2020 Elsevier Ltd. All rights reserved.

Related Products of 506-26-3, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 506-26-3 is helpful to your research.

Chemistry, like all the natural sciences, Computed Properties of C10H13Br, begins with the direct observation of nature— in this case, of matter.3972-65-4, Name is 1-Bromo-4-(tert-butyl)benzene, SMILES is CC(C1=CC=C(Br)C=C1)(C)C, belongs to bromides-buliding-blocks compound. In a document, author is Batool, Riffat, introduce the new discover.

Rumex dentatus could be a potent alternative to treatment of microbial infections and of breast cancer

OBJECTIVE: To investigate the phytochemicals and in vitro antioxidant, antimicrobial and cytotoxic potential of Rumex dentatus (R. dentatus) leaf extracts. METHODS: The total phenolics and flavonoids content of R. dentatus extracts were evaluated by the Folin-Ciocalteu and aluminum chloride colorimetric methods respectively. Antioxidant potential of studied plant extracts was assessed through 2,2-diphenyl-1-picrylhydrazyl radical scavenging capacity, total reducing power and total antioxidant methods. Moreover, antibacterial and antifungal capacity was also evaluated by disc diffusion method against six clinically isolated multi-drug bacterial strains as well as six fungal isolates. Further, cell cytotoxicity was also evaluated through 3-(4, 5-dimethylthiazolyl-2)-2, 5-diphenyltetrazoliurn bromide assay. RESULTS: Ethanol extract showed highest total phenolic [(38.9 +/- 1.5) pg gallic acid equivalent/mg] and total flavonoids [(17.2 +/- 1.9) mu g quercetin equivalent /mg] contents. Antioxidant assays indicated that ethanol and methanol extracts possess potent antioxidant potential. Moreover, it was observed that ethanol and hexane extracts have the potential to inhibit most of the tested multi-drug resistant bacterial strains while methanol, chloroform and hexane extracts could inhibit the growth of pathogenic fungal strains successfully. Among all the studied extracts, ethanolic extract showed highest cytotoxicity against MCF-7 cell line then Hep-2 and DU-145 cell lines by MTT assay with lowest IC50 of 47.3 mu g/mL. CONCLUSION: These results suggest that R. dentatus could be a potent alternative candidate for treatment of microbial infections and for breast cancer treatment. (C) 2019 JTCM. All rights reserved.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 3972-65-4. Computed Properties of C10H13Br.

Application of 3296-90-0, Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 3296-90-0, Name is Dibromoneopentyl Glycol, SMILES is OCC(CBr)(CBr)CO, belongs to bromides-buliding-blocks compound. In a article, author is Kibar, Hazal, introduce new discover of the category.

Weissella cibaria EIR/P2-derived exopolysaccharide: A novel alternative to conventional biomaterials targeting periodontal regeneration

Healing and regeneration of periodontium are considered as a complex physiological process. Therefore, treatments need to be addressed with highly effective components modulating the multiple pathways. In this study, exopolysaccharide (EPS) produced by Weissella cibaria EIR/P2, was partially purified from the culture supernatant and subjected to characterization within the aim of evaluating its potential for periodontal regeneration. High-Performance Liquid Chromatography analysis revealed a single-peak corresponding to the glucose which identified the EPS as dextran. Fourier transform-infrared spectra were also displayed characteristic peaks for polysaccharides. According to the results of gel permeation/size exclusion-chromatography, the molecular mass was determined to be 8 x 10(6) Da. To clarify its anti-bacterial activity on Streptococcus mutans, effects on viability and biofilm formation was evaluated. At 50 mg/mL, dextran exhibited a bactericidal effect with 70% inhibition on biofilm formation. Besides, dose-dependent antioxidant effects were also detected. The efficacy of dextran in enhancing the viability of human periodontal ligament fibroblast cells (hPDLFCs) was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium-bromide (MTT) assay, and an increase was observed in the viability of hPDLFCs. In conclusion, dextran derived from W. cibaria can be potentially used as a multi-functional bioactive polymer in the design of new therapeutic strategies to promote healing and regeneration of periodontium. (C) 2020 Elsevier B.V. All rights reserved.

Application of 3296-90-0, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 3296-90-0.

Chemistry can be defined as the study of matter and the changes it undergoes. You’ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 129316-09-2, Name is 1,3-Dibromo-5-(tert-butyl)benzene, molecular formula is , belongs to bromides-buliding-blocks compound. In a document, author is Kurov, K. A., Name: 1,3-Dibromo-5-(tert-butyl)benzene.

Physicochemical Characteristics of a Variant of Chaperon GroEL Apical Domain Designed to Enhance the Expression and Stability of Target Proteins

This work describes the properties of a new protein, a modification of GroEL apical domain designed to be a leader in fusion systems. This polypeptide leader demonstrates a high level of expression in a bacterial system; it is soluble and retains its solubility during standard biochemical manipulations. The secondary structure of the protein and its thermostability, as well as the protein solubility, were studied in a wide temperature range. To simplify the subsequent purification of the target protein, the possibility of its chemical cleavage from the fused protein by methionine residues with cyanogen bromide is provided.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 129316-09-2, in my other articles. Name: 1,3-Dibromo-5-(tert-butyl)benzene.

Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Recommanded Product: 1-(Bromomethyl)-2-nitrobenzene, 3958-60-9, Name is 1-(Bromomethyl)-2-nitrobenzene, SMILES is C1=CC=CC(=C1CBr)[N+](=O)[O-], belongs to bromides-buliding-blocks compound. In a document, author is Seong, Chaehyeon, introduce the new discover.

Total Synthesis of 1-Oxomiltirone and Arucadiol

A practical and efficient approach for the total synthesis of arucadiol and 1-oxomiltirone is reported. The key step which involves an intramolecular [4+2] cycloaddition catalyzed by gold(III) bromide or copper(II) triflate leads to the formation of 6-6-6-fused aromatic abietane core.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 3958-60-9. Recommanded Product: 1-(Bromomethyl)-2-nitrobenzene.