Tag: M.W=200-300

Reference of 393-36-2, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 393-36-2, Name is 4-Bromo-3-(trifluoromethyl)aniline, SMILES is C1=C(N)C=CC(=C1C(F)(F)F)Br, belongs to bromides-buliding-blocks compound. In a article, author is Shakeel, Muhammad, introduce new discover of the category.

Study of volumetric, viscometric, and aggregation properties of losartan potassium and its interaction with amino acids and cetyltrimethylammonium bromide in aqueous solution

This manuscript reports volumetric, viscometric, and aggregation properties of losartan potassium (LP) in aqueous medium and its interaction with a cationic surfactant (cetyltrimethylammonium bromide [CTAB]). Densities of drug solutions were used to calculate apparent molar volumes while constants of Jones-Dole equation were calculated from viscosity measurements. By measuring surface tension, refractive index, and electrical conductivity of drug solutions, critical micelle concentration (CMC) of drug was determined, and calculation of surface excess concentration, free energy change of adsorption, free energy change, entropy change, and enthalpy change of micellization was carried out. UV/Visible spectroscopic data were used to get an understanding about the interaction of drug with cationic surfactant (CTAB). This interaction gives an idea about the interaction of drug with biomembrane as micelles of surfactant are similar to membranes in structure. The data were also used to calculate different important parameters for drug-surfactant interaction such as partition coefficient and binding constant. Moreover, two amino acids (glycine and l-tryptophan) were used in solutions of drug separately to change its CMC. The results from volumetric and viscometric studies showed that the presence of drug in solution resulted in more organization of solvent molecules due to hydrophobic interaction. From the values of increment G degrees(ads) and increment G degrees(m), it was concluded that the adsorption of drug molecules at solution-air interface and formation of micelles occurred spontaneously. A strong drug-surfactant (LP-CTAB) interaction was observed by the attachment of drug molecules onto micellar surface of surfactant. The presence of amino acids in the solution of drug caused a decrease in the CMC of LP.

Reference of 393-36-2, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 393-36-2 is helpful to your research.

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 2635-13-4, Name is 5-Bromobenzo[d][1,3]dioxole, molecular formula is C7H5BrO2. In an article, author is Wu, Shuang,once mentioned of 2635-13-4, Name: 5-Bromobenzo[d][1,3]dioxole.

Thermodynamic modeling of the MBr-BaBr2 (M = Alkali metals) systems

The complete thermodynamic optimizations of MBr-BaBr2 (M = Li, Na, K, Rb, Cs) systems were performed based on thermodynamic principles using CALPHAD approach. In this work, the existence of BaBr2-based solid solubility was firstly evaluated according to the corresponding liquid curves in available literature by the limiting liquidus slope equation and ideal liquid curve. The liquid enthalpy of mixing for LiBr-BaBr2 binary system was calculated via empirical prediction method. The Gibbs energy of liquid molten mixtures were modeled by the substitutional solution model (SSM) and the associate solution model (ASM), while that of the double salts were processed into stoichiometric compounds based on the Neumann-Kopp technique. The thermodynamic database with a series of thermodynamic properties and phase equilibria data of investigated systems were successfully established by optimizing model parameters. The simulated results could provide theoretical guidance and technical support, as well as applying in the design for the multi-components eutectic materials by combination with the binary alkali metal bromide systems.

If you¡¯re interested in learning more about 2635-13-4. The above is the message from the blog manager. Name: 5-Bromobenzo[d][1,3]dioxole.

In an article, author is Motamedi, Zahra, once mentioned the application of 143-15-7, Name is 1-Bromododecane, molecular formula is C12H25Br, molecular weight is 249.2309, MDL number is MFCD00000225, category is bromides-buliding-blocks. Now introduce a scientific discovery about this category, Application In Synthesis of 1-Bromododecane.

Combined Effects of Protocatechuic Acid and 5-Fluorouracil on p53 Gene Expression and Apoptosis in Gastric Adenocarcinoma Cells

Objectives: This study evaluated the combined effects of protocatechuic acid (PCA) and 5-fluorouracil (5-FU) on gastric adenocarcinoma (AGS) cells. Materials and Methods: The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, colony formation assay, flow cytometry technique, real-time quantitative polymerase chain reaction, and Western blotting were used to investigate cytotoxic effects, colony formation, apoptosis, p53 gene expression, and Bcl-2 protein level in AGS cells treated with 5-FU and PCA. Results: Our results demonstrated that PCA (500 mu M) alone or in combination with 5-FU (10 mu M) inhibited AGS cell proliferation, inhibited a colony formation, and increased apoptosis compared with untreated control cells. Moreover, the combined 5-FU/PCA exposure led to upregulation of p53 and downregulation of Bcl-2 protein when compared to the untreated control cells. Conclusion: The results demonstrate that the combined 5-FU/PCA may promote antiproliferative and pro-apoptotic effects with the inhibition of colony formation in AGS cells. The mechanisms by which the combined 5-FU/PCA exposure exerts its effects are associated with upregulation of p53 gene expression and downregulation of Bcl-2 level. Therefore, the combination of 5-FU with PCA not only could be a promising approach to potentially reduce the dose requirements of 5-FU but also could promote apoptosis via p53 and Bcl-2 signaling pathways.

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Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 3296-90-0, Name is Dibromoneopentyl Glycol, molecular formula is C5H10Br2O2, belongs to bromides-buliding-blocks compound, is a common compound. In a patnet, author is Chen, Niannian, once mentioned the new application about 3296-90-0, SDS of cas: 3296-90-0.

One-dimensional polymeric iodoplumbate hybrids with lanthanide complex cations: syntheses, crystal structures, and photoelectric and photocatalytic properties

New iodoplumbate hybrids with lanthanide complexes [La(DMF)(8)]Pb3I9 (1) and [Ln(DMF)(8)]Pb5I13 (Ln = Sm (2), Gd (3)) (DMF = N,N-dimethylformamide) were prepared using octakis complex cations [Ln(DMF)(8)](3+) formed in situ as structure directing agents by volatilizing at room temperature. The polymeric 1-D [Pb3I9](n)(3n-) anion in compound 1 is constructed by PbI6 octahedral units via face-sharing featuring a waved chain structure, while the 1-D [Pb5I13](n)(3n-) anion in 2 and 3 is composed of PbI6 units via both edge-sharing and face-sharing. The compounds 1-3 show steep band gaps at 3.02, 2.61, and 2.57 eV, respectively, indicating potential semiconducting properties. They exhibit catalytic activities in the photodegradation of organic pollutants like crystal violet (CV) and methylene blue (MB). Compounds 2 and 3 are more effective than 1 in the photocatalytic degradation of CV, which are related to their intensity of the photocurrent response. The photocurrent response, cyclic voltammetry measurements and photocatalytic mechanism investigation for compound 2 show that OH radical and h(+) hole are the main reactive species in the degradation experiment of CV.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 3296-90-0. The above is the message from the blog manager. SDS of cas: 3296-90-0.

In an article, author is Keshavarz, Mojtaba, once mentioned the application of 685-87-0, Computed Properties of C7H11BrO4, Name is Diethyl 2-bromomalonate, molecular formula is C7H11BrO4, molecular weight is 239.06, MDL number is MFCD00009138, category is bromides-buliding-blocks. Now introduce a scientific discovery about this category.

The role of S100B and nitric oxide in the apoptotic action of pentylenetetrazole on astrocytes

Introduction: Astrocyte, S100B and nitric oxide may have a role in the pathogenesis and treatment of epilepsy. However, the effects of nitric oxide and S100B on the gliotoxic effects of chemical convulsants such as pentylenetetrazole (PTZ) is unknown. Therefore, we aimed to evaluate the effects of S100B and nitric oxide on gliotoxicity of PTZ in a 1321NI1 astrocytic culture. Methods: The 1321N1 astrocytes were exposed to PTZ (40mM), arundic acid (50 mu M) or both of them for 24h. In addition, we poured L-arginine (100 or 500 mu M), N-nitro-L-arginine methyl ester (100 or 500 mu M), 7-nitroindazole (30 or 100 mu M) and aminoguanidine (50 or 100 mu M) to the culture media contained PTZ, arundic acid or both of them and incubated for 24h. Cell viability was measured by the methylthiazolyldiphenyl-tetrazolium bromide reagent and the S100B protein level was measured using an enzyme-linked immunosorbent assay. Results: There was a negative correlation between cell viability in astrocytes and the intracellular S100B levels. PTZ decreased cell viability, but it increased the intracellular S100B levels. Arundic acid, N-nitroarginine methyl ester, 7-nitroindazole and aminoguanidine reversed the PTZ effects on cell viability and intracellular S100B levels. Adding the L-arginine to PTZ plus arundic acid reduced the modulatory effects of arundic acid on PTZ. Conclusion: Nitric oxide and S100B have a role in gliotoxicity of PTZ in cell culture. Arundic acid suppresses PTZ-induced S100B elevation and gliotoxicity possibly by modulation of the nitric oxide pathway.

If you are interested in 685-87-0, you can contact me at any time and look forward to more communication. Computed Properties of C7H11BrO4.

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. COA of Formula: C10H13Br, 3972-65-4, Name is 1-Bromo-4-(tert-butyl)benzene, SMILES is CC(C1=CC=C(Br)C=C1)(C)C, in an article , author is Lezov, A. A., once mentioned of 3972-65-4.

Surface active monomers: from micellar solution properties to molecular characteristics

Hydrodynamic methods and light scattering were used in the studies of solutions of a surface active monomer 11-acryloyloxyundecyltrimethylammonium bromide (AUTA-Br) and its polymers in 0.05 M NaCl. Aqueous solutions of AUTA-Br monomer in the concentration range of 4 to 16 CMC contain individual molecules and near-spherical AUTA-Br aggregates. The pAUTA-Br polymers possess rather high equilibrium rigidity (11.8 nm). This high value of equilibrium rigidity found for pAUTA-Br macromolecules is apparently caused by two factors: the presence of a bulky side substituent in each AUTA-Br monomer unit and incomplete suppression of electrostatic interactions between neighboring monomer units in the backbone.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 3972-65-4, you can contact me at any time and look forward to more communication. COA of Formula: C10H13Br.

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 3433-80-5, Name is 2-Bromobenzyl bromide, molecular formula is C7H6Br2. In an article, author is Wang, Chenyang,once mentioned of 3433-80-5, Name: 2-Bromobenzyl bromide.

A dual promotion strategy of interface modification and ion doping for efficient and stable carbon-based planar CsPbBr3 perovskite solar cells

Carbon-based all-inorganic cesium lead bromide (CsPbBr3) halide perovskite solar cells (PSCs) have attracted tremendous attention owing to their low cost, simplified preparation, and outstanding stability even under harsh conditions. However, the CsPbBr3 perovskite always suffers from an undesirable crystallization and film morphology with incomplete coverage and numerous grain boundaries. Herein, a novel dual promotion strategy combining interface modification with ion doping is proposed to achieve highly efficient and stable carbon-based planar CsPbBr3 PSCs. A thin CsBr modified layer was first inserted between the compact TiO2 (c-TiO2) and PbBr2 layers, wherein the crystallization of PbBr2 can be enhanced and then assist the growth of perovskite grains can be provided, so that CsPbBr3 films can reduce pinhole generation and accelerate carrier extraction, and decrease the hysteresis effect. Then an appropriate cobalt (Co2+) ion is doped into the CsPbBr3 film, which not only increases the grain size with decreasing grain boundary, but also ameliorates the energy level and recombination. Consequently, the champion power conversion efficiency (PCE) of the CsPbBr3 PSCs reaches up to 8.67% with an increment of about 30%. Moreover, the best-performing PSC without encapsulation also displays excellent humidity and thermal stability, maintaining above 98% of its initial PCE in an air atmosphere after 100 days, and over 95% under heat treatment at 85 degrees C after 600 hours, respectively. This study provides a promising route to boost the performance of all-inorganic perovskite solar cells.

Interested yet? Keep reading other articles of 3433-80-5, you can contact me at any time and look forward to more communication. Name: 2-Bromobenzyl bromide.

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 129316-09-2, Name is 1,3-Dibromo-5-(tert-butyl)benzene, SMILES is CC(C)(C)C1=CC(Br)=CC(Br)=C1, in an article , author is Perumal, Pearl O., once mentioned of 129316-09-2, COA of Formula: C10H12Br2.

Cytoproliferative and Anti-Oxidant Effects Induced by Tannic Acid in Human Embryonic Kidney (Hek-293) Cells

Tannic acid (TA) portrays a myriad of beneficial properties and has forthwith achieved incessant significance for its cytoprotective qualities in traditional and modern-day medicine. However, TA displays an ambiguous nature demonstrating anti-oxidant and pro-oxidant traits, beckoning further research. Although vast literature on the anti-proliferative effects of TA on cancer cell lines exist, the effects on normal cells remain unchartered. Herein, the cytoproliferative and anti-oxidant effects induced by TA in human embryonic kidney (Hek-293) cells were investigated. Data obtained from the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay demonstrated that TA increased the cell viability and cellular proliferation rate at higher concentrations. Hoechst assay, examining proliferation marker Ki67 supported these findings. DNA fragmentation and oxidative stress-inducers were specifically noted at IC25 and IC50 treatments via biochemical assays. This alluded to TA’s pro-oxidant characteristics. However, the countervailing anti-oxidant defence mechanisms as the endogenous anti-oxidants and phase2 detoxification enzymes were significantly upregulated. Luminometry fortified the anti-oxidant capacity of TA, whereby executioner caspase-3/7 were not activated subservient to the activation of initiator caspases-8 and -9. Thus, proving that TA has anti-apoptotic traits, inter alia. Therefore, TA proved to harbour anti-oxidant, anti-apoptotic, and proliferative effects in Hek-293 cells with its partial cytotoxic responses being outweighed by its cytoprotective mechanisms.

Interested yet? Read on for other articles about 129316-09-2, you can contact me at any time and look forward to more communication. COA of Formula: C10H12Br2.

Synthetic Route of 98475-07-1, Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 98475-07-1, Name is Methyl 2-(bromomethyl)-3-nitrobenzoate, SMILES is O=C(OC)C1=CC=CC([N+]([O-])=O)=C1CBr, belongs to bromides-buliding-blocks compound. In a article, author is Ling, Huan, introduce new discover of the category.

A transparent-to-gray electrochromic device based on an asymmetric viologen

A transparent-to-gray electrochromic device (ECD) based on an asymmetric viologen was fabricated and characterized. The core material derived from novel bipyridine salt (named 1-(2-(diethoxy-phosphoryl)ethyl)-1 ‘-(4-vinylbenzyl)-[4,4 ‘-bipyridine]-1,1 ‘-diium chloride bromide, DVB) combined with complementary species of ferrocene was assembled in a device with a simple configuration of ITO/EC solution/ITO. The device was first converted to blue color from transparent when 1.0 V was applied, and then neutral gray color when the potential bias was increased to 2.0 V. Meanwhile, the corresponding optical contrasts (Delta T) were 54.5% and 22% at 392 nm and 605 nm, respectively. In addition, a good coloration efficiency of 128.9 cm(2) C-1 at 2.0 V and fast switching time (<2.5 s) were obtained. Finally, satisfied stability with 43.8% of Delta T (maintaining 80% of initial Delta T at 392 nm) was achieved after 2000 cyclic processes, which paves a new way to design colorless to neutral color ECDs. Synthetic Route of 98475-07-1, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 98475-07-1 is helpful to your research.

Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Recommanded Product: 941-37-7, 941-37-7, Name is 1-Bromo-3,5-dimethyladamantane, molecular formula is C12H19Br, belongs to bromides-buliding-blocks compound. In a document, author is Bai, Yu-huan, introduce the new discover.

A novel oncolytic adenovirus inhibits hepatocellular carcinoma growth

Objective To evaluate the inhibitory role of a novel oncolytic adenovirus (OA), GP73-SphK1sR-Ad5, on the growth of hepatocellular carcinoma (HCC). Methods GP73-SphK1sR-Ad5 was constructed by integrating Golgi protein 73 (GP73) promoter and sphingosine kinase 1 (SphK1)-short hairpin RNA (shRNA) into adenovirus serotype 5 (Ad5), and transfecting into HCC Huh7 cells and normal human liver HL-7702 cells. The expression of SphK1 and adenovirus early region 1 (E1A) was detected by quantitative real-time PCR (qRT-PCR) and western blot, respectively. Cell viability was detected by methylthiazolyldiphenyl-tetrazolium bromide (MTT) assay, and apoptotic rate was determined by flow cytometry. An Huh7 xenograft model was established in mice injected intratumorally with GP73-SphK1sR-Ad5. Twenty days after injection, the tumor volume and weight, and the survival time of the mice were recorded. The histopathological changes in tumor tissues were observed by hematoxylin-eosin (HE) staining and transmission electron microscopy (TEM). Results Transfection of GP73-SphK1sR-Ad5 significantly upregulated E1A and downregulated SphK1 in Huh7 cells, but not in HL7702 cells. GP73-SphK1sR-Ad5 transfection significantly decreased the viability and increased the apoptotic rate of Huh7 cells, but had no effect on HL7702 cells. Intratumoral injection of GP73-SphK1sR-Ad5 into the Huh7 xenograft mouse model significantly decreased tumor volume and weight, and prolonged survival time. It also significantly decreased the tumor infiltration area and blood vessel density, and increased the percentages of cells with nucleus deformation and cells with condensed chromatin in tumor tissues. Conclusions GP73-SphK1sR-Ad5 serves as a novel OA and can inhibit HCC progression with high specificity and efficacy.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 941-37-7. Recommanded Product: 941-37-7.