Tag: M.W=300-350

Zhou, Jinjun published the artcileTuning Energy Levels of Low Bandgap Semi-Random Two Acceptor Copolymers, Application of 2,5-Dibromo-3,4-dinitrothiophene, the publication is Macromolecules (Washington, DC, United States) (2013), 46(9), 3391-3394, database is CAplus.

A series of low bandgap semi-random copolymers incorporating various ratios of two acceptor units – thienothiadiazole and benzothiadiazole – were synthesized by Pd-catalyzed Stille coupling. The polymer films exhibited broad and intense absorption spectra, covering the spectral range from 350 nm up to 1240 nm. The optical bandgaps and HOMO levels of the polymers were calculated from UV-visible spectroscopy and cyclic voltammetry measurements, resp. By changing the ratio of the two acceptor monomers, the HOMO levels of the polymers were tuned from -4.42 to -5.28 eV and the optical bandgaps were varied from 1.00 to 1.14 eV. The results indicate our approach could be applied to the design and preparation of conjugated polymers with specifically desired energy levels and bandgaps for photovoltaic applications.

Macromolecules (Washington, DC, United States) published new progress about 52431-30-8. 52431-30-8 belongs to bromides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 2,5-Dibromo-3,4-dinitrothiophene, and the molecular formula is C11H16BNO3S, Application of 2,5-Dibromo-3,4-dinitrothiophene.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Wang, Guanghui published the artcileDouble N,B-Type Bidentate Boryl Ligands Enabling a Highly Active Iridium Catalyst for C-H Borylation, SDS of cas: 401797-04-4, the publication is Journal of the American Chemical Society (2015), 137(25), 8058-8061, database is CAplus and MEDLINE.

Boryl ligands hold promise in catalysis due to their very high electron-donating property. In this communication double N,B-type boryl anions were designed as bidentate ligands to promote an sp² C-H borylation reaction. A sym. pyridine-containing tetraaminodiborane(4) compound was readily prepared as the ligand precursor that could be used, in combination with [Ir(OMe)(COD)]₂, to in situ generate a highly active catalyst for a broad range of (hetero)arene substrates including highly electron-rich and/or sterically hindered ones. This work provides the 1st example of a bidentate boryl ligand in supporting homogeneous organometallic catalysis.

Journal of the American Chemical Society published new progress about 401797-04-4. 401797-04-4 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzene,Ether,Boronate Esters,Boronic acid and ester, name is 2-(3-Bromo-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, and the molecular formula is C8H11BO2, SDS of cas: 401797-04-4.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Xue, Ding published the artcileDiscovery and Lead Optimization of Benzene-1,4-disulfonamides as Oxidative Phosphorylation Inhibitors, Quality Control of 1178100-39-4, the publication is Journal of Medicinal Chemistry (2022), 65(1), 343-368, database is CAplus and MEDLINE.

Inhibition of oxidative phosphorylation (OXPHOS) is a promising therapeutic strategy for select cancers that are dependent on aerobic metabolism Here, we report the discovery, optimization, and structure-activity relationship (SAR) study of a series of novel OXPHOS inhibitors. The hit compound, benzene-1,4-disulfonamide 1 (I), was discovered in a phenotypic screen selective for cytotoxicity in a galactose-containing medium. Our multi-parameter optimization campaign led to the discovery of 65 (DX3-235)(II), showing nanomolar inhibition of complex I function and ATP production in a galactose-containing medium resulting in significant cytotoxicity. Importantly, 64 (DX3-234)(III), a close analog of 65, is well tolerated in mice and shows significant single agent efficacy in a Pan02 syngeneic pancreatic cancer model, suggesting that highly potent and selective OXPHOS inhibitors can be useful for the treatment of pancreatic cancer.

Journal of Medicinal Chemistry published new progress about 1178100-39-4. 1178100-39-4 belongs to bromides-buliding-blocks, auxiliary class Bromide,Sulfamide,Amine,Benzene, name is 4-Bromo-N,N-diethyl-3-methylbenzenesulfonamide, and the molecular formula is C9H9BrO2, Quality Control of 1178100-39-4.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Xie, Ke published the artcilePoly(3,4-dinitrothiophene)/SWCNT composite as a low overpotential hydrogen evolution metal-free catalyst, Quality Control of 52431-30-8, the publication is Journal of Materials Chemistry A: Materials for Energy and Sustainability (2015), 3(1), 78-82, database is CAplus.

A novel metal-free H evolution reaction catalyst made of poly(3,4-dinitrothiophene)/SWCNT was developed. This catalyst presents a good H evolution reaction activity with a lower overpotential than metallic catalysts. Its performance was optimized to an overpotential of ∼0.040 V and a H generation rate of 44.2 μmol h^-1 cm^-2.

Journal of Materials Chemistry A: Materials for Energy and Sustainability published new progress about 52431-30-8. 52431-30-8 belongs to bromides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 2,5-Dibromo-3,4-dinitrothiophene, and the molecular formula is C9H9NO, Quality Control of 52431-30-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Li, Zhitao published the artcileAnalysis of coal tar pitch and smoke extract components and their cytotoxicity on human bronchial epithelial cells, Formula: C4Br2N2O4S, the publication is Journal of Hazardous Materials (2011), 186(2-3), 1277-1282, database is CAplus and MEDLINE.

Coal tar pitch and its smoke are considered hazardous byproducts and common pollutants generated by the coal processing industry. This work characterized coal tar pitch and its smoke extracts by gas chromatog./mass spectrometry (GC/MS) using dimethylsulfoxide. Only 0.3025% of components in total coal tar pitch were identified by GC/MS. Among 18 identified compounds, polycyclic aromatic hydrocarbons (PAH) has the highest relative abundance (0.19%). Remaining components were composed of monocyclic aromatic hydrocarbons, heterocyclic compounds, and alkenes. Among 38 coal tar pitch smoke extract constituents profiled, 87.91% were PAH; the remaining 12.09% were composed of monocyclic aromatic hydrocarbons, heterocyclic compounds, and alkenes. The cytotoxic effect of coal tar pitch and its smoke extracts on BEAS-2B cells were also evaluated using the MTT assay. BEAS-2B cells exposed to coal tar pitch exhibited a non dose-dependent, U-shaped cytotoxicity with the maximum ID of 3.75 mg/L. BEAS-2B cells exposed to coal tar pitch smoke extracts exhibited dose-dependent cytotoxicity with a 8.64 mg/L LC₅₀. Results demonstrated the significant different composition and cytotoxicity of coal tar pitch and its extracts, suggesting 2 underlying mechanisms which are pending future investigation.

Journal of Hazardous Materials published new progress about 52431-30-8. 52431-30-8 belongs to bromides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 2,5-Dibromo-3,4-dinitrothiophene, and the molecular formula is C4Br2N2O4S, Formula: C4Br2N2O4S.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Gao, Baoxiang published the artcileBand gap tunable for near-infrared absorbing chromophores with multi-triphenylamine and tris (thieno)hexaazatriphenylenes acceptors, HPLC of Formula: 52431-30-8, the publication is Tetrahedron Letters (2010), 51(14), 1919-1921, database is CAplus.

Two disk-like D-A type chromophores with multi-triphenylamine donors and hexaazatriphenylene acceptors were synthesized and fully characterized by ¹H and ¹³C NMR, elemental anal. and mass spectrometry. The effects of the hexaazatriphenylene on the optical and electrochem. properties and band gap of the chromophores were investigated. As the hexaazatriphenylene core fused with three thiophene rings, the band gaps of the compounds could be tuned from 1.65 eV to 1.15 eV. The π-π* absorption peak and charge-transfer absorption peak of the hexaazatriphenylene compounds were red shifted from visible spectrum region (393 and 530 nm) to near-IR spectrum region (542 and 756 nm). In addition, due to an increase in the π electronic coupling between electron donor and electron acceptor, the extinction coefficient (charge-transfer absorption) of the hexaazatriphenylene compound decreases 85% from 3.4 × 10⁴ mol^-1 dm^-3 cm^-1 to 0.5 × 10⁴ mol^-1 dm^-3 cm^-1.

Tetrahedron Letters published new progress about 52431-30-8. 52431-30-8 belongs to bromides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 2,5-Dibromo-3,4-dinitrothiophene, and the molecular formula is C4Br2N2O4S, HPLC of Formula: 52431-30-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Chen, Xin published the artcileSynthesis of PEGylated Salicylaldehyde Azine via Metal-free Click Chemistry for Cellular Imaging Applications, Category: bromides-buliding-blocks, the publication is Chemical Research in Chinese Universities (2019), 35(5), 929-936, database is CAplus.

In this work, two kinds of PEGylated salicylaldehyde azine(SA) polymers were prepared and investigated for cellular imaging applications. First, a diazido derivative of SA was synthesized and subsequently PEGylated with polyethylene glycol monomethyl ether(mPEG) by metal-free azide-alkyne 1,3-dipolar cycloaddition reaction. The formed triazole group in mPEG-SA was then converted into cationic triazolium group by N-alkylation reaction. Both the synthesized polymers, mPEG-SA and N-alkylated mPEG-SA, showed good dispersibility in water, but differences in self-assembly of nanostructures. The mPEG-SA with triazole groups self-assembled into micelles, while the N-alkylated mPEG-SA with triazolium groups self-assembled into vesicles. Furthermore, mPEG-SA and N-alkylated mPEG-SA nanoparticles showed bright fluorescence due to the aggregation of AIE-active SA mols. in the nano-particles and could be successfully used as fluorescent nanoprobes for bioimaging applications in HeLa cancer cells. Finally, both the synthesized polymers showed minimal cytotoxicity and low hemolytic activity. Therefore, these PEGylated SA polymers proved to be promising bioimaging nanoprobes or traceable drug delivery vehicles.

Chemical Research in Chinese Universities published new progress about 1207448-58-5. 1207448-58-5 belongs to bromides-buliding-blocks, auxiliary class Bromide,Benzene,Phenol,Ether,Aldehyde, name is 4-((6-Bromohexyl)oxy)-2-hydroxybenzaldehyde, and the molecular formula is C13H17BrO3, Category: bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Luecke, Ana-Luiza published the artcilePalladium complexes of anionic N-heterocyclic carbenes derived from sydnones in catalysis, Quality Control of 52431-30-8, the publication is Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences (2016), 71(6), 643-650, database is CAplus.

The anion of N-phenylsydnone, which can be generated on treatment of N-phenylsydnone with cyanomethyllithium without decomposition, can be represented as tripolar zwitterionic and as anionic N-heterocyclic carbene resonance forms. Its Pd complex was prepared from 4-bromo-3-phenylsydnone and tetrakis(triphenylphosphine)palladium and is active as catalyst in Suzuki-Miyaura reactions. Thus, 2,5-dibromo-3,4-dinitrothiophene was effectively converted into 2,5-diaryl-3,4-dinitrothiophenes with 1-naphthyl-, (4-trifluoromethoxy)phenyl-, [4-(methylsulfanyl)phenyl]- and (biphenyl-4-yl)boronic acid. 3-(Phenanthren-9-yl)quinoline was prepared by Suzuki-Miyaura reaction starting from 3-bromoquinoline. 1-Chloro-2,4-dinitrobenzene cross-coupled with Ph boronic acid, 1-naphthylboronic acid and 9-phenanthrylboronic acid. 4-Bromobenzylic alc. gave (4-isopropylphenyl)methanol on sydnone-Pd complex-catalyzed reaction with iso-Pr boronic acid.

Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences published new progress about 52431-30-8. 52431-30-8 belongs to bromides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 2,5-Dibromo-3,4-dinitrothiophene, and the molecular formula is C4Br2N2O4S, Quality Control of 52431-30-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Schluetter, Florian published the artcileSynthesis and Characterization of New Self-Assembled Metallo-Polymers Containing Electron-Withdrawing and Electron-Donating Bis(terpyridine) Zinc(II) Moieties, Recommanded Product: 2,5-Dibromo-3,4-dinitrothiophene, the publication is Macromolecules (Washington, DC, United States) (2010), 43(6), 2759-2771, database is CAplus.

A series of rigid π-conjugated bis(terpyridines) (M1-M7) bearing electron-acceptor spacer units in 4′-position was synthesized in moderate to high yields by Pd⁰-catalyzed Sonogashira cross-coupling reactions. The compounds were fully characterized by NMR spectroscopy, MALDI-TOF mass spectrometry, elemental anal. and their photophys. properties were discussed in detail. These new bis(terpyridines) were applied for the self-assembly reaction with Zn^II ions to form metallo-homo polymers (P1-P7). Broadened NMR signals and UV-vis titration experiments confirmed the successful polymerization The electro-optical properties of the materials were investigated in detail. Band gaps up to 2.08 eV and bright blue to orange photoluminescence with quantum yields of 18 to 66% were observed strongly depending on the nature of the π-conjugated bis(terpyridine) system. In combination with electron-donor ditopic terpyridine ligands (MD1 and MD2), two Zn^II random copolymers (R1 and R2) were synthesized. These materials were investigated by UV-vis absorption and photoluminescence experiments in dilute solution and in the solid state, prepared by spin-coating from DMF solutions Thereby, random copolymer R2 featured an energy transfer from the donor to the acceptor part in dilute solution

Macromolecules (Washington, DC, United States) published new progress about 52431-30-8. 52431-30-8 belongs to bromides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 2,5-Dibromo-3,4-dinitrothiophene, and the molecular formula is C4Br2N2O4S, Recommanded Product: 2,5-Dibromo-3,4-dinitrothiophene.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Bauer, Heiko published the artcileChromocene, ferrocene, cobaltocene, and nickelocene derivatives with isopropyl and methyl or trimethylsilyl substituents, Application of Cobalt(II) dibromo(1,2-dimethoxyethane), the publication is Journal of Organometallic Chemistry (2016), 63-73, database is CAplus.

From sodium 2,3-diisopropyl-1,4-dimethyl-cyclopentadienide and MBr₂(dme) (M = Fe, Co, Ni) the corresponding ferrocene (1), cobaltocene (2) and nickelocene (3) could be obtained as pure, crystalline solids. From an analogous reaction of sodium 2,3,5-triisopropyl-1,4-dimethyl-cyclopentadienide with FeCl₂, only the mixed-substituted ferrocene (³₂Cp)(²₂Cp)Fe (4) could be crystallized (³₂Cp = 2,3,5-triisopropyl-1,4-dimethyl-cyclopentadienyl, ²₂Cp = 2,3-diisopropyl-1,4-dimethyl-cyclopentadienyl). The trimethylsilyl substituted ferrocene (5) and nickelocene (6) were synthesized from the corresponding metal halides and potassium 2,3-diisopropyl-1,4-dimethyl-5-trimethylsilyl-cyclopentadienide as well as a series of chromocenes with silylated or alkylated cyclopentadienyl ligands (7–10) from chromium(II) acetate. Octaisopropylnickelocene (11) has been obtained and converted to octaisopropylnickelocenium hexafluorophosphate (12). 1,2,3,4-Tetraisopropylnickelocenium tetrabromoaluminate (13) was obtained from tetraisopropylcyclopentadienylnickel(II) tetrabromoaluminate and nickelocene. Crystal structures have been obtained for metallocenes 1–5, 7–9, and 11.

Journal of Organometallic Chemistry published new progress about 18346-57-1. 18346-57-1 belongs to bromides-buliding-blocks, auxiliary class Cobalt, name is Cobalt(II) dibromo(1,2-dimethoxyethane), and the molecular formula is C4H10Br2CoO2, Application of Cobalt(II) dibromo(1,2-dimethoxyethane).

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary