Tag: M.W=350-400

Zhang, Chen published the artcileDesign, Synthesis, and Evaluation of a Series of Novel Benzocyclobutene Derivatives as General Anesthetics, Application of Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, the publication is Journal of Medicinal Chemistry (2017), 60(9), 3618-3625, database is CAplus and MEDLINE.

In the present work, a series of structurally novel benzocyclobutene derivatives were identified as general anesthetics through the loss of righting reflex (LORR) experiment on mice. Our initial efforts found compound 1a with a fused four-membered ring on the 2,3-position of the phenol ring could significantly improve the safety profile. Further SAR study revealed that small hydrogen bond acceptor (HBA) groups are optimal for good ED₅₀ along with much broader therapeutic windows, such as compounds 16b and 17. Present work demonstrates the superiority of this novel benzocyclobutene scaffold.

Journal of Medicinal Chemistry published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C6H5N3S, Application of Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Li, Zonglong published the artcileThree-Dimensional Ionic Covalent Organic Frameworks for Rapid, Reversible, and Selective Ion Exchange, Related Products of bromides-buliding-blocks, the publication is Journal of the American Chemical Society (2017), 139(49), 17771-17774, database is CAplus and MEDLINE.

Covalent organic frameworks (COFs) have emerged as functional materials for various potential applications. However, the availability of three-dimensional (3D) COFs is still limited, and nearly all of them exhibit neutral porous skeletons. Here we report a general strategy to design porous pos. charged 3D ionic COFs by incorporation of cationic monomers in the framework. The obtained 3D COFs are built of 3-fold interpenetrated diamond net and show impressive surface area and CO₂ uptakes. The ion-exchange ability of 3D ionic COFs has been highlighted by reversible removal of nuclear waste model ions and excellent size-selective capture for anionic pollutants. This research thereby provides a new perspective to explore 3D COFs as a versatile type of ion-exchange materials.

Journal of the American Chemical Society published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, Related Products of bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Thiemann, Thies published the artcileStudies towards dibenzothiophene S-oxide arrays and their photochemical reactivity, Category: bromides-buliding-blocks, the publication is Kyushu Daigaku Kino Busshitsu Kagaku Kenkyusho Hokoku (2001), 15(1), 63-71, database is CAplus.

A novel access to oligo(dibenzothiophenes) is described Here, the trimethylsilyl-group is used both as positional protective group and as a directive group which can be exchanged. The reagents benzyltrimethylammonium tribromide (BTMABr₃) and benzyltrimethylammonium iododichloride (BTMAICl₂) are used for the first time in silyl-halo exchange reactions. The dimeric, trimeric and tetrameric dibenzothiophene building blocks are prepared by Suzuki-Kumada C-C coupling reactions. Exemplary oxygenations of these building blocks to the corresponding dibenzothiophene S-oxides is shown.

Kyushu Daigaku Kino Busshitsu Kagaku Kenkyusho Hokoku published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C4H7BrO2, Category: bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Miura, Yozo published the artcilePyridyl-Substituted Thioaminyl Stable Free Radicals: Isolation, ESR Spectra, and Magnetic Characterization, Name: Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, the publication is Journal of Organic Chemistry (1998), 63(23), 8295-8303, database is CAplus.

N-[(4-Nitrophenyl)thio]- (1a) and N-[(2,4-dichlorophenyl)thio]-2,6-diphenyl-4-(3-pyridyl)phenylaminyl (1b), N-[(4-nitrophenyl)thio]- (2a) and N-[(2,4-dichlorophenyl)thio]-4-phenyl-2,6-di(3-pyridyl)phenylaminyl (2b), and N-[(2,4-dichlorophenyl)thio]-2,6-diphenyl(4-pyridyl)aminyl (3) were generated by PbO₂ oxidation of the corresponding precursors. Although 3 was not sufficiently stable to be isolated, both 1 and 2 persisted in solution without decomposition and could be isolated as radical crystals. X-ray crystallog. anal. of 1b revealed that the Ar-N-S-Ar’ π-framework is approx. planar and the 2- and 6-Ph groups are significantly twisted from this plane. The magnetic susceptibility measurements for the isolated radical crystals were carried out using a SQUID magnetometer in the temperature range 1.8-300 K. The susceptibilities of 1a and 2a were explained in terms of a 1-dimensional (1D) antiferromagnetic (AFM) regular Heisenberg model with an exchange interaction of 2J/k_B = -63.4 and -17.8 K, resp., and that of 1b was interpreted in terms of a 1-dimensional AFM alternating Heisenberg model with 2J/k_B = -12.8 K and α (alternation parameter) = 0.91. However, that of 2b was explained in terms of a 1-dimensional ferromagnetic regular Heisenberg model with 2J/k_B = 22.4 K.

Journal of Organic Chemistry published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Name: Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Miura, Yozo published the artcilePurely organic magnetism of pyridyl-substituted stable thioaminyl radicals, Application In Synthesis of 111865-47-5, the publication is Molecular Crystals and Liquid Crystals Science and Technology, Section A: Molecular Crystals and Liquid Crystals (1999), 195-204, database is CAplus.

N-[(4-Nitrophenyl)thio]- (1a) and N-[(2,4-dichlorophenyl)(thio)]-2,6-diphenyl-4-(3-pyridyl)phenylaminyl (1b), N-[(4-nitrophenyl)thio]- (2a) and N-[(2,4-dichlorophenyl)thio]-4-phenyl-2,6-di(3-pyridyl)phenylaminyl (2b) were generated by PbO₂ oxidation of the corresponding precursors and isolated as radical crystals. For 1b x-ray crystallog. anal. was performed. The magnetic susceptibility measurements were carried out for the isolated radicals using a SQUID magnetometer at 1.8-300 K. The susceptibilities of 1a and 2a were analyzed in terms of a 1-dimensional (1D) antiferromagnetic (AFM) regular Heisenberg model with exchange interaction of 2J/k_B=-63.4 and -17.8 K, resp., and that of 1b was interpreted in terms of a 1-dimensional AFM alternating Heisenberg model with 2J/k_B = -12.8 K and α 0.91. However, that of 2b was explained in terms of a 1-dimensional ferromagnetic regular Heisenberg model with 2J/k_B = 22.4 K.

Molecular Crystals and Liquid Crystals Science and Technology, Section A: Molecular Crystals and Liquid Crystals published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Application In Synthesis of 111865-47-5.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Saito, Hitoshi published the artcileFacile synthesis of fluorene-based π-conjugated polymers via sequential bromination/direct arylation polycondensation, Safety of Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, the publication is Journal of Polymer Science, Part A: Polymer Chemistry (2015), 53(19), 2198-2201, database is CAplus.

The synthesis of fluorene-based p-conjugated polymers via sequential bromination and direct arylation was demonstrated. Bromination of 9,9-dioctylfluorene using BTMA Br3 efficiently proceeded and barely inhibited the following direct arylation polycondensation, successfully giving π-conjugated polymers. This is the first example of the facile synthesis of π-conjugated polymers in a one-pot fashion, without the need for prior preparation and purification of dibrominated aromatic monomers as well as organometallic monomers, and the bromination reaction using BTMA Br3 is also available to other aromatic compounds such as thiophene and carbazole derivatives Therefore, the fundamental step-economical protocol described here should present new insights for the synthesis of π-conjugated semiconducting materials.

Journal of Polymer Science, Part A: Polymer Chemistry published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Safety of Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Tripathi, Ayushi published the artcileOptimization of Thermoelectric Properties of Polymers by Incorporating Oligoethylene Glycol Side Chains and Sequential Solution Doping with Preannealing Treatment, SDS of cas: 111865-47-5, the publication is Macromolecules (Washington, DC, United States) (2020), 53(16), 7063-7072, database is CAplus.

Two types of p-type thermoelec. (TE) polymers with alkyl (PCPDTSBT) and oligoethylene glycol (OEG) side chains (PCPDTSBT-A) on an sp²-hybridized olefinic bis(alkylsulfanyl)methylene-substituted cyclopentadithiophene backbone are synthesized. Interestingly, the OEG-substituted polymer, PCPDTSBT-A, exhibits significant self-doping compared to PCPDTSBT, where the polaron d. of the former is 2.3 × 10¹⁶ mm^-3 (vs. 7.9 × 10¹⁴ mm^-3 for PCPDTSBT) without external doping. Changing the side chains also induces a completely different polymer chain orientation in the PCPDTSBT-A (face-on) and PCPDTSBT (edge-on) films. The effect of doping with 2,3,5,6-tetrafluoro-7,7,8,8-tetracyanoquinodimethane (F₄TCNQ) on the morphol. and TE properties of the polymers with different side chains is studied. Sequential solution doping (SQD) is performed by overcoating the preannealed polymer films with F₄TCNQ solution, which affords highly effective doping without disrupting the morphol. of the crystalline films, especially for PCPDTSBT-A with OEG side chains. Resulting from the synergistic effect of the OEG side chains and SQD, PCPDTSBT-A exhibits remarkably improved elec. conductivity (53.8 S cm^-1) with a higher power factor (40.4μW m^-1 K^-2), compared to PCPDTSBT, for which the maximum elec. conductivity is 1.4 S cm^-1 and the power factor is 1.8μW m^-1 K^-2. In addition, the transport coefficient of PCPDTSBT-A, determined by applying the Kang-Snyder model (2.40 × 10^-2 S cm^-1), is superior to that of PCPDTSBT (3.59 × 10^-3 S cm^-1), thereby showing the excellence of the developed strategy for improving the performance of TE polymers.

Macromolecules (Washington, DC, United States) published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C16H14O6, SDS of cas: 111865-47-5.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Kakinami, Takaaki published the artcileSelective bromination of aromatic amines by use of tetrabutylammonium tribromide and benzyltrimethylammonium tribromide, Recommanded Product: Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, the publication is Ube Kogyo Koto Senmon Gakko Kenkyu Hokoku (1989), 37-45, database is CAplus.

The title reactions in CH₂Cl₂-MeOH containing powd. CaCO₃ at room temperature gave, selectively, the mono-, di-, or tribromo-substituted aromatic amines in good yields.

Ube Kogyo Koto Senmon Gakko Kenkyu Hokoku published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Recommanded Product: Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Garg, Dimple published the artcileKinetics and mechanism of the oxidation of some α-amino acids by benzyltrimethylammonium tribromide, HPLC of Formula: 111865-47-5, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (2005), 44B(9), 1909-1914, database is CAplus.

The oxidation of nine α-amino acids by benzyltrimethylammonium tribromide (BTMAB), in aqueous acetic acid, gives the corresponding aldehydes. The reaction is first order with respect to BTMAB. Michaelis-Menten type kinetics are observed with respect to the amino acids. The thermodn. parameters for the complex formation and the activation parameters for the decomposition of complex were determined An addition of benzyltrimethylammonium ion does not affect the rate. The oxidation of perdeuterioglycine shows the absence of a kinetic isotope effect (k_H/k_D = 1.05 at 313 K). The effect of solvent composition indicates that the reaction rate increases with an increase in the polarity of the medium. The reaction is susceptible to both polar and steric effects of the substituents. Suitable mechanism was proposed.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, HPLC of Formula: 111865-47-5.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Goel, Shruti published the artcileKinetics and mechanism of oxidation of some α-hydroxy acids by benzyltrimethylammonium tribromide, Product Details of C10H16Br3N, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1996), 35B(11), 1180-1184, database is CAplus.

The oxidation of glycolic acid, lactic acid, 2-hydroxy-2-methylpropanoic acid, mandelic acid and nine monosubstituted mandelic acids by benzyltrimethylammonium tribromide (BTMAB) in 1:1 (volume/volume) acetic acid-water leads to the formation of the corresponding carbonyl compounds The reaction is first order with respect to BTMAB. Michaelis-Menten type kinetics have been observed with respect to the hydroxy acid. The rates of decomposition of the complexes show an excellent correlation with Hammett’s σ values with low neg. reaction constants The oxidation of α-deuteriomandelic acid indicates the absence of a kinetic isotope effect. The reaction shows a substantial solvent isotope effect (k(H₂O)/k(D₂O) = 3.57 at 313 K). With an increase in the proportion of acetic acid in the solvent mixture of acetic acid and water, the rate decreases. Addition of benzyltrimethylammonium ion has no effect on the reaction rate. The reaction fails to induce the polymerization of acrylonitrile. A suitable mechanism has been proposed.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Product Details of C10H16Br3N.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary