Tag: M.W=350-400

Goswami, Garima published the artcileKinetics and mechanism of the oxidation of some diols by benzyltrimethylammonium tribromide, Safety of Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, the publication is Proceedings – Indian Academy of Sciences, Chemical Sciences (2001), 113(1), 43-54, database is CAplus.

The kinetics of oxidation of five vicinal and four non-vicinal diols, and two of their monoethers by benzyltrimethylammonium tribromide (BTMAB) have been studied in 3:7 (volume/volume) acetic acid-water mixture The vicinal diols yield the carbonyl compounds arising out of the glycol bond fission while the other diols give the hydroxycarbonyl compounds The reaction is first-order with respect to BTMAB. Michaelis-Menten type kinetics is observed with respect to diol. Addition of benzyltrimethylammonium chloride does not affect the rate. Tribromide ion is postulated to be the reactive oxidizing species. Oxidation of [1,1,2,2-²H₄] ethanediol shows the absence of a kinetic isotope effect. The reaction exhibits substantial solvent isotope effect. A mechanism involving a glycol-bond fission has been proposed for the oxidation of the vicinal diols. The other diols are oxidized by a hydride ion transfer to the oxidant, as are the monohydric alcs.

Proceedings – Indian Academy of Sciences, Chemical Sciences published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Safety of Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Goswami, Garima published the artcileKinetics and mechanism of oxidation of aliphatic aldehydes by benzyltrimethylammonium tribromide, HPLC of Formula: 111865-47-5, the publication is Journal of Chemical Research, Synopses (1999), 176-177, 813-833, database is CAplus.

The oxidation of aliphatic aldehydes by benzyltrimethylammonium tribromide involves the formation of an intermediate complex and its subsequent decomposition in the rate-determining step to the corresponding carboxylic acid.

Journal of Chemical Research, Synopses published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, HPLC of Formula: 111865-47-5.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Goyal, Archana published the artcileKinetics and mechanism of the oxidation of methionine by benzyltrimethylammonium tribromide, Formula: C10H16Br3N, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (2003), 42B(9), 2129-2132, database is CAplus.

The oxidation of methionine (MTN) by benzyltrimethylammonium tribromide (BTMAB), in 1:1 aqueous acetic acid, gives the corresponding sulfoxide. The reaction is first order with respect to each the methionine and BTMAB. The oxidation of MTN in an atm. of N, failed to induce the polymerization of acrylonitrile. An addition of benzyltrimethylammonium chloride has no effect on the rate of oxidation The rates of oxidation were determined at different temperatures and the activation parameters were calculated The reaction rate increases with an increase in the polarity of the medium. Tribromide ion is postulated as the reactive oxidizing species. Suitable mechanism for the reaction is postulated.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Formula: C10H16Br3N.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Mehla, Satish K. published the artcileCorrelation analysis of reactivity in the oxidation of substituted benzaldehydes by benzyltrimethylammonium tribromide, Category: bromides-buliding-blocks, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (2002), 41B(4), 832-838, database is CAplus.

The oxidation of benzaldehyde and thirty-five monosubstituted benzaldehydes by benzyltrimethylammonium tribromide (BTMAB) in aqueous acetic acid gives the corresponding benzoic acids. The reaction is first order with respect to each the benzaldehyde and BTMAB. The reaction failed to induce the polymerization of acrylonitrile. There is no effect of benzyltrimethylammonium chloride on the reaction rate. The oxidation of [²H]benzaldehyde (PhCDO) indicated the presence of a substantial kinetic isotope effect. The effect of solvent composition indicated that the reaction rate increases with an increase in the polarity of the solvent. The rates of oxidation of meta- and para-substituted benzaldehydes are correlated in terms of Charton’s triparametric LDR equation whereas the oxidation of ortho-substituted benzaldehydes are correlated with tetraparametric LDRS equation. The oxidation of para- substituted benzaldehydes is more susceptible to the delocalization effect than is the oxidation of ortho-and meta-substituted compounds, which display a greater dependence on the field effect. The pos. value of η suggests an electron-deficient reaction center in the rate-determining step. The reaction is subjected to steric hindrance by the ortho-substituents.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Category: bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Sankhla, Rekha published the artcileCorrelation analysis of reactivity in the oxidation of substituted benzylamines by benzyltrimethylammonium tribromide, Product Details of C10H16Br3N, the publication is Indian Journal of Chemistry, Section A: Inorganic, Bio-inorganic, Physical, Theoretical & Analytical Chemistry (2002), 41A(3), 541-546, database is CAplus.

The oxidation of benzylamine and twenty-seven ortho-, meta- and para-monosubstituted benzylamines by benzyltrimethylammonium tribromide (BTMAB), in dimethylsulfoxide (DMSO), gives corresponding aldimines. The reaction is first order with respect to both BTMAB and the amine. The oxidation of deuterated benzylamine exhibited a substantial kinetic isotope effect. Addition of benzyltrimethylammonium bromide does not affect the rate. Tribromide ion was postulated as the reactive oxidizing species. The rates of the oxidation of para- and meta-substituted benzylamines showed excellent correlation in terms of both Taft’s dual substituent-parameter and Charton’s triparametric LDR equations, whereas the ortho-substituted compounds exhibited the best correlation with the Charton’s tetraparametric LDRS equation. The oxidation of para-substituted benzylamines is more susceptible to the delocalization effect than is the oxidation of ortho- and meta-substituted compounds, which display a greater dependence on the field effect. The low pos. value of the η suggests an electron-deficient center in the rate-determining transition state with less charge separation A suitable mechanism was proposed.

Indian Journal of Chemistry, Section A: Inorganic, Bio-inorganic, Physical, Theoretical & Analytical Chemistry published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Product Details of C10H16Br3N.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Suri, Deepa published the artcileKinetics and mechanism of the oxidation of formic and oxalic acids by benzyltrimethylammonium tribromide, Quality Control of 111865-47-5, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1998), 37B(5), 448-452, database is CAplus.

The oxidation of formic and oxalic acids by benzyltrimethylammonium tribromide (BTMAB) leads to the formation of carbon dioxide. The reaction is first order with respect to BTMAB. Michaelis-Menten type kinetics are observed with respect to substrate. The values of the formation constants for the organic acid-BTMAB complexes and the rates of their decomposition, at different temperatures, have been determined Oxidation of α-deuterioformic acid indicated the presence of a primary kinetic isotope effect (k_H/k_D = 6.03 at 298 K). With an increase in the polarity of solvent, the formation constants for the complexes decrease however, their rates of decomposition increase. Suitable mechanisms involving the formation of acyclic and cyclic intermediates in the oxidations of formic and oxalic acids resp., have been proposed.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C6H8O3, Quality Control of 111865-47-5.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Nishida, Akiko published the artcileHalogenation using quaternary ammonium polyhalides. XXVIII. Effect of substituents on brominating ability of quaternary ammonium tribromides, Recommanded Product: Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, the publication is Technology Reports of the Yamaguchi University (1990), 4(4), 303-8, database is CAplus.

Trimethylammonium tribromides RC₆H₄R¹ (I) [R = 4-Me, 4-NO₂, R¹ = (CH₂NMe₃)⁺Br₃^–, (NMe₃)⁺Br₃^–] were prepared and served as brominating reagents for 2-methoxyphenol (II). Thus, I [R = 4-Me, R¹ = (CH₂NMe₃)⁺Br₃^–] (III) was prepared by condensing 4-MeC₆H₄CH₂Br with NMe₃ followed by treatment with NaBrO₃/HBr. III brominated II to give 4,6-dibromo-2-methoxyphenol. The brominating ability of these compounds was compared to the corresponding phenylanalogs I [R = H, R¹ = (CH₂NMe₃)⁺Br₃^–, (NMe₃)⁺Br₃^–].

Technology Reports of the Yamaguchi University published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Recommanded Product: Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Boebel, Timothy A. published the artcileIridium-Catalyzed Preparation of Silylboranes by Silane Borylation and Their Use in the Catalytic Borylation of Arenes, Quality Control of 1075719-78-6, the publication is Organometallics (2008), 27(22), 6013-6019, database is CAplus.

Silylboranes are versatile reagents for transition metal-catalyzed reactions of unsaturated organic mols. These reagents are typically prepared by the addition of a silyl lithium species to a boron electrophile. However, the need to generate anionic silane reagents limits the scope of silylboranes that can be readily obtained. Here, the synthesis of trialkylsilylboranes by borylation of silanes catalyzed by iridium complexes is described. The reaction of trialkylhydrosilanes with B₂pin₂ catalyzed by the combination of [Ir(OMe)cod]₂ and 4,4′-di-tert-butylbipyridine forms trialkylsilylboronic esters. In addition, these trialkylsilylboranes serve as boron sources for iridium-catalyzed borylation of aryl C-H bonds. In contrast to diboron reagents, the silylboranes react with methylarenes at both the aryl and Me C-H bonds.

Organometallics published new progress about 1075719-78-6. 1075719-78-6 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzene,Boronate Esters,Boronic Acids,Boronic acid and ester, name is 2-(3,4-Dibromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, and the molecular formula is C12H15BBr2O2, Quality Control of 1075719-78-6.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Ponce, Yovani Marrero published the artcileAtom-based 2D quadratic indices in drug discovery of novel tyrosinase inhibitors: results of In Silico studies supported by experimental results, Quality Control of 518-67-2, the publication is QSAR & Combinatorial Science (2007), 26(4), 469-487, database is CAplus.

Herein we present results of QSAR studies of tyrosinase inhibitors employing one of the atom-based TOMOCOMD-CARDD (acronym of TOpol. Mol. COMputer Design-Computer Aided “Rational” Drug Design) descriptors, mol. quadratic indexes, and Linear Discriminant Anal. (LDA) as pattern recognition method. In this way, a database of 246 organic chems., reported as tyrosinase inhibitors having great structural variability, was analyzed and presented as a helpful tool, not only for theor. chemists but also for other researchers in this area. In total, 12 LDA-based QSAR models were obtained, the first six with the non-stochastic total and local quadratic indexes and the six remaining models with the stochastic mol. descriptors. The best two models for the non-stochastic and stochastic mol. descriptors, showed an appropriate overall accuracy (92.68 and 89.10%, resp.) and a high Matthews correlation coefficient (C of 0.85 and of 0.84, correspondingly) when applied to the training set. External validation series were also used to validate the obtained models; the 91.67% (C = 0.82) and 90.00% (C = 0.78), were correctly classified, resp. To show the possibilities of the present approach for the ligand-based virtual screening of tyrosinase inhibitors, the developed models were used afterwards in a simulation of a virtual search for tyrosinase inhibitors. For instance, more than 93% (93.33%) and 96% (96.66%) of the screened chems. were correctly classified by the two best LDA-based QSAR models developed with non-stochastic and stochastic quadratic indexes, resp. Finally, the combination of the obtained models permitted the selection/identification of new diterpenoidal alkaloid leads as tyrosinase inhibitors. The found activity is supported by observed inhibitory effects on mushroom tyrosinase enzyme, even comparable with some reference tyrosinase inhibitors. These results support a role for TOMOCOMD-CARDD descriptors in the biosilico discovery of novel tyrosinase inhibitors from large databases of chem. structures (virtual or “in silico”), which may be used to prevent or treat pigmentation disorders.

QSAR & Combinatorial Science published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, Quality Control of 518-67-2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Erickson, Paul R. published the artcilePhotochemical Formation of Brominated Dioxins and Other Products of Concern from Hydroxylated Polybrominated Diphenyl Ethers (OH-PBDEs), Safety of Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, the publication is Environmental Science & Technology (2012), 46(15), 8174-8180, database is CAplus and MEDLINE.

The photochem. conversion of selected hydroxylated polybrominated di-Ph ethers (OH-PBDEs) to dioxins and other products was investigated. OH-PBDEs, which are both transformation products of polybrominated di-Ph ethers and naturally occurring compounds, undergo direct photolysis to yield a number of products that may have a higher toxicity than their parent. The compounds investigated were 6-OH-PBDE 99, 6′-OH-PBDE 100, and 6′-OH-PBDE 118. Of special interest was 6′-OH-PBDE 118, a potential transformation product of PBDE 153 that is capable of photochem. generating 2,3,7,8-tetrabromodibenzo-p-dioxin, the most toxic brominated dioxin congener. Photolysis experiments were conducted at two different pH values to assess the photochem. behavior of both the phenol and phenolate form of the compounds The percent conversion to dioxin and other photoproducts was determined and the natural product, 6-OH-PBDE 99, was found to have the highest conversion to dioxin (7%). The reaction quantum yields ranged from 0.027 to 0.16 across all photolysis conditions. In addition, it is shown that all three compounds are capable of photochem. generating other compounds of concern, including brominated phenols and a dibenzofuran.

Environmental Science & Technology published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Safety of Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary