In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1435-51-4, name is 1,3-Dibromo-5-fluorobenzene belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Product Details of 1435-51-4
step 1-A solution of 50a, sodium methoxide (1 equivalent) and DMF were stirred overnight under an N2 atmosphere at RT. The volatile solvents were removed in vacuo and the residue partitioned between Et2O and water. The organic phase was washed with 5% NaOH, water and brine, dried (MgSO4), filtered and evaporated to afford 50b.
The synthetic route of 1435-51-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Saito, Yoshihito David; Smith, Mark; Sweeney, Zachary Kevin; US2007/78128; (2007); A1;,
Bromide – Wikipedia,
bromide – Wiktionary