2550-36-9, name is (Bromomethyl)cyclohexane, belongs to bromides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. category: bromides-buliding-blocks
General procedure: To a solution of 9d (94 mg, 0.49 mmol) and potassium tert-butoxide (55 mg, 0.49 mmol) in anhydrous THF (10 mL) under argon was added benzyl bromide (0.06 mL, 0.54 mmol). The mixture was stirred at room temperature and monitored by TLC until complete. The solution was concentrated and dichloromethane (20 mL) was added. The organic layer was washed with water, dried (MgSO4), and evaporated under reduced pressure to afford the crude product which was purified on a silica gel column (5% MeOH/dichloromethane). The desired product was isolated as a white solid (83 mg, 60%).
The synthetic route of 2550-36-9 has been constantly updated, and we look forward to future research findings.
Reference:
Article; White, Alex W.; Carpenter, Nicholas; Lottin, Jerome R. P.; McClelland, Richard A.; Nicholson, Robert I.; European Journal of Medicinal Chemistry; vol. 56; (2012); p. 246 – 253,8;,
Bromide – Wikipedia,
bromide – Wiktionary