Perez, Alexander J. published the artcileω-Azido fatty acids as probes to detect fatty acid biosynthesis, degradation, and modification, COA of Formula: C15H29BrO2, the main research area is omega azido fatty acid biosynthesis metabolism HPLC MS; S-azidoacyl-N-acetylcysteamine; azido-fatty acids; click-chemistry; cyclooctyne; fatty acid desaturation; fatty acid metabolism; strained promoted cycloadditon; β-oxidation.
FAs play a central role in the metabolism of almost all known cellular life forms. Although GC-MS is regarded as a standard method for FA anal., other methods, such as HPLC/MS, are nowadays widespread but are rarely applied to FA anal. Here we present azido-FAs as probes that can be used to study FA biosynthesis (elongation, desaturation) or degradation (β-oxidation) upon their uptake, activation, and metabolic conversion. These azido-FAs are readily accessible by chem. synthesis and their metabolic products can be easily detected after click-chem. based derivatization with high sensitivity by HPLC/MS, contributing a powerful tool to FA anal., and hence, lipid anal. in general.
Journal of Lipid Research published new progress about High-performance liquid chromatography-mass spectrometry. 56523-59-2 belongs to class bromides-buliding-blocks, name is 15-Bromopentadecanoic acid, and the molecular formula is C15H29BrO2, COA of Formula: C15H29BrO2.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary