Robinson, Matthew P. published the artcileAu-Catalyzed Oxidative Arylation: Chelation-Induced Turnover of ortho-Substituted Arylsilanes, Category: bromides-buliding-blocks, the main research area is thiophene arylsilane oxidative arylation gold; arylthiophene preparation; gold oxidative arylation catalyst.
Ortho-Substituted aryl silanes have previously been found to undergo much slower Au-catalyzed intermol. arylation than their m,p-substituted isomers, with many examples failing to undergo turnover at all. A method to indirectly quantify the rates of C-Si auration of o-substituted aryl silanes, under conditions of turnover, has been developed. All examples are found to undergo very efficient C-Si auration, indicative that it is the subsequent C-H auration that is inhibited by the ortho substituent. A simple Ar-Au conformational model suggests that C-H auration can be accelerated by chelation. A series of ortho-functionalized aryl silanes are shown to undergo efficient arylation.
ACS Catalysis published new progress about Arylation catalysts (Oxidative). 452-63-1 belongs to class bromides-buliding-blocks, name is 1-Bromo-4-fluoro-2-methylbenzene, and the molecular formula is C7H6BrF, Category: bromides-buliding-blocks.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary